Results 21 to 30 of about 4,801,388 (251)
Targeted anti-vascular therapies for ovarian cancer: current evidence [PDF]
, 2013 Ovarian cancer presents at advanced stage in around 75% of women, and despite improvements in treatments such as chemotherapy, the 5-year survival from the disease in women diagnosed between 1996 and 1999 in England and Wales was only 36%.Mcneish, I., Gore, M., M Hall, Gore, M, C Gourley, Hall, M, Kaye, S, Gourley, C., Ledermann, J, McNeish, I, Jayson, G.; id_orcid, Gourley, C, G Jayson, Jayson, G., Kaye, S., Rustin, G, M Gore, J Ledermann, S Kaye, Perren, T, I McNeish, Hall, M., G Rustin, Rustin, G., Perren, T., T Perren, Jayson, G, Ledermann, J. +27 morecore +1 more sourceProgesterone prevents HGSOC by promoting precancerous cell pyroptosis via inducing fibroblast paracrine
iScience, 2023 Summary: High-grade serous ovarian carcinoma (HGSOC) is one of the most fatal gynecological cancers and has no effective prevention strategies. Herein, we demonstrated that progesterone significantly inhibited the occurrence, metastasis, and ascites of ...Nayiyuan Wu, Xiaoye Zhang, Zhibin Wang, Xiu Zhang, Chao Fang, He Li, Miaochen Zhu, Ying Wang, Qianjin Liao, Tangyuan Chu, Jing Wang +10 moredoaj +1 more sourceGenome-Wide Association Study in BRCA1 Mutation Carriers Identifies Novel Loci Associated with Breast and Ovarian Cancer Risk [PDF]
, 2013 BRCA1-associated breast and ovarian cancer risks can be modified by common genetic variants. To identify further cancer risk-modifying loci, we performed a multi-stage GWAS of 11,705 BRCA1 carriers (of whom 5,920 were diagnosed with breast and 1,839 were Side, Lucy E.,, Investigators, k, Pastinen, Tomi, Van Os, Theo A.M., D. F. Easton (7608179), J. Balmana, Ute Hamann (89879), Volorio, Sara, A. Lasa, SWE-BRCA, Tihomirova, L, Imyanitov, E.N., Moeller, ST, L. Senter, Friedlander, M., Muy-Kheng Tea, Barrowdale, D., Öfverholm, Anna, Aittomaki, K., N. Tung, J. Lester, C. F. Singer (7619636), T. Huzarski (7676663), Douglas, F., Shimon Paluch, Shani,, Frans B L Hogervorst, Barkardottir, Rosa B, C. Houdayer (7658699), Pascal Pujol, Dreyfus, Hélène, H. Thorne, Murday, Victoria, Viel, Alessandra, Heli Nevanlinna, Rouleau, E, Shani Shimon Paluch (395262), Yuan Chun Ding (322601), de la Hoya, Miguel, P. Pujol, Capucine Delnatte (395234), Georgia Chenevix-Trench (361), Rita Katharina Schmutzler (395199), Paolo Peterlongo, Kerstin Rhiem (112049), Imyanitov, Evgeny N., Z. Miedzybrodzka, Bonanni, Bernardo, C. Lazaro, Adam Lee, Beattie, Mary S.,, Arnold, N, Caldes, Trinidad,, Dezheng Huo (151859), Sinilnikova, O. M., Pascaline Berthet (395233), J. Garber (7608110), Chung, Wendy K., Arver, Brita, Zachary Fredericksen (146612), Diana M. Eccles (219472), Pujol, P, Sand, S, A. E. Toland (7608026), Niederacher, D, A. Lucassen, Lubinski, Jan, D. E. Cohn (7676702), Tihomirova, L., Miguel de la Hoya, D. Gareth Evans (154186), Ausems, M. G E M, T. Pastinen (7608953), Marco Montagna (238698), Berthet, Pascaline, Taylor, Jane, L. Venat Bouvet, A. Meindl (7619555), Slager, Susan L, B. Bonanni (1681321), Weber, Bernhard HF, Brewer, C., Mulligan, A.M., Sabine Preisler-Adams (395251), Bernhard H. F. Weber (162289), Osorio, A, Hardouin, A, Pastinen, T., Peissel, Bernhard, Kristiina Aittomäki, Esther M John, Mazoyer, S, Friebel, T, Lidereau, Rosette, Blanco, I, Jonson, L, Gaudet, Mia M.,, Patrick J Morrison, Lee, A, Christian F. Singer (308365), Platte, Radke, M. C. Southey (7608080), Lenka Foretova (162255), Platte, Radka, Liljegren, Annelie, Huzarski, Tomasz, Tibiletti, MG, Lebrun, Marine, K. Kohut, Spurdle, Amanda B, Y. Laitman (7608005), Pujol, Pascal,, Ewart Toland, A., M. Tischkowitz, Alexandra V. Stavropoulou (387774), O. Caron, C. Seynaeve, S. V. Blank, Jan Lubinski (59925), C. M. Kets, Berthet, P., L. Snadden, Daphne Gschwantler-Kaulich, A. Romero (3572522), J. Benitez, Wijnen, JT, Singer C.F., Guimbaud, Rosine, Susan L Neuhausen, Frans B. L. Hogervorst (146390), D. Frost, Mortemousque, Isabelle, Coupier, Isabelle,, F. Prieur, et al., Ignacio Blanco, Donaldson, A, M. Lebrun, E. Castro, A. M. Mulligan, Peissel, Bernard,, Fredericksen, Z, Pujana, Miquel Angel, Zakaria Einbeigi, Andrea Gehrig, Stoppa-Lyonnet D., Eeles, RA, Teo, Soo-Hwang,, M. J. Blok, C. Nogues (2482849), E. Niedermayr, Handallou, Sandrine, Wiggins, Jennifer, Kwong, A., Varon-Mateeva, R, Olopade, O.I., C. Engel (7619549), R. Platte (7608131), Kruse, Torben A, Maria Grazia Tibiletti (395246), Cunningham, Julie, Leone, Melanie,, S. Hart, Kristiina Aittomäki (89889), Kuchenbaecker, K. B., Montagna, M., Tomasz Huzarski, Dennis, Joe,, Robson, Mark,, A. Gehrig (7676681), van Asperen, C. J., K. Jaworska, Gadzicki, D., Mette K. Andersen (395271), Lindor, Noralane M, David E Cohn, Vincent, Daniel,, Pankratz, Vernon S, Mia M. Gaudet (146621), Soucy, Penny, E. Fineberg (7658291), Blok, Marinus J.,, Raymonda Varon-Mateeva, S. A. Narod, Rouleau, Etienne,, G. Glendon, Jernström, Helena, Sokolowska, Johanna, Moeller, S, Pujana, M.A., Uhrhammer, Nancy, Haque, Eshika, Buys, SS, Kruse, T.A., Ligtenberg, Marjolijn JL, Vijai, Joseph,, D. Mcbride, T. M. Friebel, M. K. Tea (7619639), Robson, Mark, S. M. Domchek, Sue Healey, A. Murray, Gerdes, Anne-Marie, Jaworska, Katarzyna,, Kara Sarrel, Douglas, Fiona,, Hall, Per, Rookus, M. A., L. Foretova (7676744), S. R. Sand, Lindblom, Annika, Laurie Small, Toulas, Christine, A. M. Dunning (7658231), Adlard, Julian,, Ottini, Laura,, Verhoef, S, Janavicius, R, R. Rosenquist (7652192), Prieur, Fabienne, Nogues, Catherine, S. T. Moeller, Hodgson, Shirley,, Morrison, Patrick J., L. E. Side, D. Huo (7676804), Godwin, Andrew K, C. Toulas, Christian Sutter, J. Adlard (7619510), Meindl, A, Hart, Steven,, Shimon Paluch, S, Mai, Phuong L, F. Bacot (7658246), F. Prieur (7658807), Venat-Bouvet, Laurence,, Szabo, C.I., Kathleen Claes (203063), G. Pfeiler (7658321), Goldgar, David E, Os, T.A. van, Sharon R Sand, Evans, Gareth; id_orcid, Ehrencrona, Hans, Susan J Ramus, A. Donaldson (6262271), Kruse, T, A. Hardouin, Sharon R. Sand (395278), Karin Kast (112042), H. T. Lynch, Barkardottir, R, Z. Fredericksen (7619612), Andersen, MK, Southey, Melissa C., Jaworska, K., Gaudet, MM, Ligtenberg, MJL, Jocelyne Chiquette, M. Porteous, Lars Jønson (395270), Inge Sokilde Pedersen, Tara M. Friebel (395289), A. P. Sokolenko (7676810), Isabelle Coupier (292499), S. Goff, M. J. Blok (7658489), Rosa B Barkardottir, O. Diez (7676606), Ellis, S, Drummond, Sarah, Anna Marie Mulligan (146672), Gerdes, Anne-Marie,, Domchek, SM, Izatt, Luise, Douglas F. Easton (89956), Catherine M. Phelan (219497), Traasdahl Moeller, Sanne, Frans B. L. Hogervorst, L. Varesco (7676669), Melissa C Southey, Os, T. A.,, Christine Lasset, Laurence Venat-Bouvet (395240), Mélanie Léoné (395241), Sinilnikova O.M., S. Goodman, Bubien, Virginie, N. Tung (7608077), Tung, Nadine,, K. Sarrel, Paluch, Shani Shimon, Muranen, TA, Ausems, M.G., Marc Tischkowitz, Szabo, Csilla I, G. Dite, Jacqueline Eason, Hogervorst, F.B., Gomez Garcia, E.B., L. Side, Laurie Small (395257), A. K. Godwin (7608119), Tibiletti, M, I. Blanco, K. Rhiem (7619546), Laitman, Y., Borg, Åke, Kosel, Matthew, Sutter, C., M. G. E. M. Ausems, Anne-Marie Gerdes, S. Preisler Adams, Stefanie Engert (112037), A. V. Stavropoulou (7676780), Chen, Wang, Finn C Nielsen, V. S. Pankratz, Piedmonte, Marion,, V. Bubien, Gibson, Sarah, Coupier, I., N. Ditsch, Hogervorst, Frans B L, M. Leone, K. Durda (7676657), Mads Thomassen, Ellis, Ian, Meindl, Alfons,, Dicks E., Wendy K Chung, M. Soller, Mazoyer, S., Devilee, Peter,, Pastinen, Tomi,, B. Arver (7619687), Gadzicki, D, Jakubowska, Anna,, Searle, Anne, Alexander Miron (28179), J. Cunningham (7676831), C. Jacobs, Fergus J Couch, A. De Pauw, S. B. Chan, Eitan Friedman (196582), Hansen, TV, Rensburg, E. J.,, McLeod, Diane, Neuhausen, Susan L.,, Alison M. Dunning (146796), Terry, MB, M. Piedmonte, Złowocka-Perłowska, Elżbieta, Hansen, TVO, S. L. Slager, Vijai, Joseph, Antoniou, AC, Dorfling, C.M., L. E. Side (7619534), T. Noguchi, Złowocka-Perlowska, Elz bieta, Pujol, Pascal, Olswold, C, S. Giraud, Hansen, T.V.O., Ava Kwong (52115), J. Simard, Feillel, Viviane, Antoniou, A., Nogues, C., Mary S Beattie, Domchek, S, Adlard, Julian, M. B. Daly (7608074), Laitman, Yael,, Frost, D, Silvia Tognazzo (395279), D. Stoppa-Lyonnet (7608194), S. J. Ramus (7608041), Neuhausen, S, Cook, J., M. K. Schmidt, Wang, Xianshu, Ottini, L, Karlan, BY, B. Peissel (7619426), J. De Lange, Schmutzler, R. K., Benitez, Javier, Papi, L., F. E. van Leeuwen (7658432), Grazia Tibiletti, Maria,, Ontario Canc Genetics Network, Volorio, S., T. C. T. E. F. Van Cronenburg, Lee, A., Kristoffersson, Ulf, Lenka Foretova, Nielsen, FC, Jonson, L., A. Osorio (7608089), Miquel Angel Pujana (395274), Finn C. Nielsen (206969), Mulligan, AM, Dieter Niederacher (93623), Teo, S.H., Slager, SL, H. Ozcelik (7608029), Angel Pujana, Miquel, EMBRACE (Epidemiological Study of Familial Breast Cancer), Pascal Pujol (8444), Sandra Orsulic, G. Rea, P. Hall (7508258), Izatt, Louise, Huo, D., Southey, M. C., Kaufman, B, Pensotti, Valeria, Jenny Lester (395276), Pfeiler, Georg, Beth Y. Karlan (184236), Sutter, C, Kientz, Caroline, Manoukian, Siranoush,, Longmuir, Mark, T. M. Friebel (7676819), Ganz, P.A., M. J. Kennedy, N. Loman (7676693), Weaver, Joellen, T. Huzarski, E. Olah, S. Hodgson (7633343), Stephanie V Blank, Bernhard H F Weber, Sokolenko, Anna P., Huo, DZ, Houghton, Catherine,, Ontario Cancer Genetics Network, Durda, K., J. T. Wijnen (7658285), C. Rappaport (7676717), Teule, Alex, Hamann, Ute, Pujana, MA, Singer, Christian F, Norbert Arnold, Dennis, Joe, H. Nevanlinna, S. Shimon Paluch (7676723), Rouleau, Etienne, Theo A. M. van Os (395220), Peissel, Bernard, Blanco, I., Buys, S, Stenmark-Askmalm, M., H. Gregory, Miron, A., Orsulic, Sandra,, Ganz, PA, Narod, S.A., Nadine Tung (238710), Ramus, S.J., van Rensburg, Elisabeth J., N. Sevenet, B. H. Weber (7676690), J. Dennis (7658234), Gregory, Helen,, Annemarie H van der Hout, Alexander Miron, Chun Ding, Yuan, C. H. van Deurzen (7676618), Kruse, Torben A.,, Y. C. Ding (7619387), Weaver, J, Flora E. van Leeuwen (248404), Raymonda Varon-Mateeva (196729), van Os, Theo AM, Ramus, Susan J, E. Rouleau (7658759), Noah Kauff, Rosenquist, Richard,, Blok, M.J., E. B. Gomez Garcia, Lasset, C, C. Berlin, Cohn, D.E., Caroline Seynaeve, Arun, Banu K, Trinidad Caldes, Soucy, Penny,, van Leeuwen, Flora E, S. B. Chan (7676807), Hall, P., van Deurzen, C, Walsh, C, Jeffrey N. Weitzel (238722), Francesca Damiola, Soller, Maria, Hansen T.V.O., N. Kauff (7619633), Joe Dennis, Agnès Hardouin, Hansen, Thomas VO, Engert, Stefanie, K. Offit, B. H. F. Weber, L. Izatt (7608137), M. K. Andersen, Vincent, D., Mary Beth Terry (2801), Karin Kast, Friedman E., J. P. Fricker, Huw Dorkins, Olufunmilayo I. Olopade (151873), Aittomäki, K, Hogervorst, FB, Hilmi Ozcelik (20185), Huo, Dezheng, Stenmark-Askmalm, M, S. H. Teo (7675199), Pedersen, IS, M. Belotti, Bent Ejlertsen, Teule, A., Encarna B. Gómez Garcia (5654410), Olah, E., C. M. Phelan, Jacqueline Eason (238727), Montagna, M, I. S. Pedersen (7676726), Ejlertsen, B, E. Friedman (7608035), Anneliese Fink-Retter, L. Foretova, Friedman, Eitan,, Peterlongo, Paolo,, Beattie, MS, Engert, Stefanie,, Spurdle, Amanda B.,, Steven A. Narod (230773), E. N. Imyanitov (7676600), Jackie Cook, al., et, Rosalind A Eeles, K. Henriksson, Rebbeck, Timothy R.,, van Deurzen, Carolien H. M., F. B. Hogervorst (7608212), Wijnen, J.T., Barbara Wappenschmidt, Meindl, Alfons, Eitan Friedman, Blank, Stephanie V, S. Shimon Paluch, Timothy R. Rebbeck (230766), Lazaro, Conxi, Olah, E, Radice P., Zlowocka-Perlowska, E, Jensen, U, Agata, S, Orsulic, S., Ejlertsen, Bent,, F. Douglas (7658597), Kristen Stevens, Eason, J, Soucy, P., B. Bressac De Paillerets, James, Margaret, Paolo Radice (146601), E. Zlowocka Perlowska, Gille, JJP, Hansjoerg Plendl (395250), Złowowcka-Perłowska, Elzbieta, L. Small, Ausems, Magreet G. E. M., Paluch, SS, Friebel, TM, Conxi Lazaro (3405329), Daly, Mary B.,, Vaszko, T, C. Sutter, Agnès Hardouin (395232), Friebel, T.M., Preisler-Adams, S., Glendon, Gord, Greene, M.H., Marinus J. Blok (395217), Nevanlinna, H., Hoya, M. de la, Yves-Jean Bignon (54433), I. L. Andrulis (7608020), von Wachenfeldt, Anna, Lars Jønson, Sutter, Christian,, McGuffog, Lesley, Karlan, B. Y., Fabienne Prieur (246641), Lazaro, C (Conxi), Hilmi Ozcelik, Bacot, Francois,, Collaborators, GEMOS, Bourdon, Violaine, Lee, Andrew, Jensen, UB, Herzog, J, Bacot, Françios, Lucassen, Anneke, Simard, Jacques,, Friedlander, Michael, Theo A M van Os, Xianshu Wang (146610), Olga M Sinilnikova, Steele, L, Waisfisz, Q., Platte, R, Lubinski, Jan,, C. Tirapo, Meijers-Heijboer, H. E., Bacot, F., Blank, SV, A. Calender, Singer, CF, Joan Brunet (75020), M. Kosel (7676585), A. Brady, Hanne E J Meijers-Heijboer, Einbeigi, Z, Blanco, Ignacio, A. P. Sokolenko, Penny Soucy (21792), Andrulis, IL, Steele, L., Weber, B.H., Caroline Seynaeve (95368), Singer, Christian F.,, S. M. Domchek (7608044), Loud, J.T., Domchek S.M., Anne-Bine Skytte (395263), Hart, Steven, Rappaport, C, Szabo, C. I., M. Emanuelsson, Tea, Muy Kheng, Gille, JJ, J. Paterson, Ausems, Margreet GEM, Ava Kwong, Judith Balmaña (395210), Demange, Liliane, Goldgar, D, Ramus, Susan J., Thomas V O Hansen, Sylvie Mazoyer, S. Manoukian, Dorfling, CM, Loman, N., N. M. Lindor (7619618), Preisler-Adams, Sabine, Pankratz, V.S., Martin, Sue, Hansen, Thomas V O, Goldgar, DE, N. M. Lindor, Sobol, Hagay, Easton, D.F., O. I. Olopade (7607978), Castera, L., Sabine Preisler-Adams, Cunningham, J, O. I. Olopade, Jonson, Lars,, S. Agata, C. Houghton, J. T. Loud, Chenevix-Trench, G., Curtis Olswold (73571), Kulkarni, Anjana, Ausems, MGEM, Sinilnikova, O.M., J. Chiquette, Glendon, G, Ding, Y.C., S. Tognazzo (7619591), Imyanitov, EN, Wang X., Anneliese Fink-Retter (395258), M. H. Greene (7608092), Muranen, T.A., J. Herzog (7676765), Ellis, Steve,, S. Handallou, kConFab Investigators, C. Lasset, M. Stenmark Askmalm, Fournier, Joëlle, Montagna, Marco,, Christoph Engel, Edith Olah (395204), Bignon, Y, Kets, C. M., D. Yannoukakos, J. Maskiell, C. Brewer (7658534), Kenneth Offit (63812), van Rensburg, E, Kauff, N., D. Frost (7608128), Ausems, M.G.E.M., Lehmann, Anna, X. Wang (770484), A. Ewart Toland, Garcia, EBG, Andrulis, Irene L, V. L. Bae-Jump (7676714), Zachary Fredericksen, Elena Fineberg, Side, Lucy, Prieur, Fabienne,, Carole Brewer, Senno Verhoef (395219), T. A. Kruse (6179165), de Pauw, Antoine, HEBON (Hereditary Breast and Ovarian Cancer Research Group Netherlands), Dunning, A.M., Karlan, Beth Y, Piedmonte, M, A. Osorio, E. Kivuva, Orsulic, Sandra, van Rensburg, EJ, Moeller, S.T., J. M. Collee, van Leeuwen, F.E., Stormorken, Astrid, Marc Tischkowitz (395208), A. V. Stavropoulou, Josef Herzog (395277), Osorio, Ana, Soo-Hwang Teo (266270), Offit, Kenneth, Dicks, Ed,, Hogervorst, F. B L, Ozcelik, Hilmi,, Vaszko, Tibor, Murray, Alexandra, Debra Frost, Stevens, Kristen,, Orland Diez (395209), Phuong L. Mai (238716), Ramus, Susan J.,, Mercedes Duran, van Rensburg, E.J., Sobol, Hagay,, D. Vincent (2350123), Janavicius, Ramunas, Barrowdale, D, Brady, Angela, Beattie, M, Jaworska, K, Steve Ellis, P. A. Ganz (7619606), Kast, K., A. B. Skytte, Spurdle, AB, Soucy, P, Chung, W.K., Sarrel, Kara,, D. E. Cohn, Gaudet, M. M., Beattie, M. S., Elena Fineberg (395222), Senter, L, P. Peterlongo, F. Soubrier, Hagay Sobol, Evans, DG, Healey S., Ardern-Jones, Audrey, Sara Volorio (255289), Nadine Tung, Prieur, F, Joe Dennis (395193), S. Smalley, Nathanson, Katherine L.,, Hamann, Ute,, Rookus, Matti A.,, Valeria Pensotti (395247), S. Mazoyer, Weber, BHF, A. Melville, Josef Herzog, Nina Ditsch, Terry, M. B., K. Kast (7619507), Phelan, Catherine M.,, Neuhausen, Susan L., de Lange, J., Christian Sutter (196732), Miron, A, Mercedes Duran (5651374), Bignon, Yves-Jean,, Olufunmilayo I Olopade, Greene, Mark H.,, Agata, S., Isabelle Coupier, Gille, Johannes J.P., J. T. Wijnen, Mulligan, A, Engel, Christoph,, Hodgson, Shirley, Melin, Beatrice, Shirley Hodgson, Alex Murray (395230), L. Tihomirova (7676816), Fineberg, E., Antoniou, Antonis C, Andrew Lee (74302), C. Delnatte, A. Liljegren, Dorfling, Cecilia M.,, M. Piedmonte (7607933), Rogers, M.T., Paterson, Joan, Hogervorst, FBL, M. Duran, L. Winchester, Dennis, J, K. Hill, Thomassen, Mads,, K. Kast, N. Rahman, van Leeuwen, F. E., Capucine Delnatte, Nielsen, F, BCFR, Mazoyer, Sylvie,, M. Gauthier Villars, Trinidad Caldes (3147195), Gaudet, Mia M, Evgeny N Imyanitov, M. G. Tibiletti, Venat-Bouvet, L, K. Aittomaki, Gerdes, A.-M., Angel Pujana, Miquel,, Richard Rosenquist (262592), Stavropoulou, Alexandra V., Side, Lucy E., Mary B. Daly (196724), M. A. Pujana (7676753), Kruse, TA, Tihomirova, Laima, Mourits, M. J., Preisler-Adams, S, James, Paul A, Richard Rosenquist, Weitzel, Jeffrey N, Faivre, Laurence, Ellis, Steve, Leone, M., Kenneth Offit, M. B. Daly, Mai, P.L., Kuchenbaecker, Karoline B.,, Walker, Lisa, V. Attard, Marion Piedmonte, Eeles, R. A., B. Stayner, Jeffers, Lisa, L. Castera (7676645), Susan M. Domchek (154078), Murray, Alex,, J. Rantala, B. Buecher, Drakoulis Yannoukakos (4758), K. Harbst, A. Remenieras, J. N. Weitzel (7608107), Mia M. Gaudet, A. Jakubowska (7658414), Nathanson, K.L., Robson, M., Easton, Douglas F, J. Gronwald (7676654), Christian F Singer, Morrison, P.J., R. Davidson, Chenevix-Trench, G, Teule, Alex,, Phelan, C, Marion Piedmonte (238646), Ditsch, Nina,, Teo, Soo-Hwang, Matthew Kosel, Lester, Jenny,, Norbert Arnold (112045), K. Stevens (4256824), Eccles, DM, Plendl, Hansjoerg, M. B. Terry (7608047), Arver, B., I. S. Pedersen, Gauthier-Villars, Marion, F. Douglas, Gustavo C Rodriguez, K. B. Kuchenbaecker (7658228), Cohn, David E.,, Peter Devilee, McGuffog, Lesley,, Gehrig, A, Dominique Stoppa Lyonnet, E. J. van Rensburg (7658273), A. M. W. Van Den Ouweland, Olswold, Curtis,, Meijers-Heijboer, Hanne EJ, Einbeigi, Zakaria,, Dorkins, Huw,, Healey, S., Schmutzler R.K., Jacques Simard, Rodriguez, Gustavo C, Susan J. Ramus (205214), Devilee, Peter, Tripathi, Vishakha, Bignon, Y.J., Taru A. Muranen (395284), Karlan, B, Vincent, D, van Rensburg, Elizabeth J, Peissel, B., Hagay Sobol (91961), Daly, M. B., S. Preisler-Adams (7619522), Gehrig, Andrea,, Leroux, Dominique, Tischkowitz, M., C. E. Ardnor, Aalfs, C. M., Glendon, G., Lindor, Noralane M.,, Fergus J. Couch (146607), Angel Pujana, M., M. S. Beattie, B. A. Agnarsson (7676822), Lasset, Christine, T. R. Rebbeck, Blanco, Ingnacio, Stenmark-Askmalm, Marie, Castro, Elena, Louise Izatt, N. Ditsch (7676684), Kosel, M, Sara Volorio, Dorfling, Cecilia M, Antonis C. Antoniou (146788), David E. Cohn (395255), Damiola, Francesca, Andersen, M, Lasa, Adriana, G. Crawford, Mary S. Beattie (395206), Rouleau, E., Amanda Ewart Toland (164514), Katarzyna Jaworska (146755), Balmana, J., Durda, Katarzyna,, Couch, Fergus J., SWE-BRCA (7619690), Buys, Saundra S., Ramus, SJ, A. Searle, B. Bonanni, Remenieras, Audrey, R. B. Barkardottir, Houghton, C, Laitman, Y, J. Cunningham, Douglas, Fiona, Yannoukakos, D, S. Volorio, Karoline B. Kuchenbaecker (395191), Szabo, C, D. Eccles, Loud, Jennifer T, Georgia, Chenevix-Trench, Houlston, Richard, Montagna, Marco, Duran, M, Hamann, U., van Os, Theo A. M., C. Lasset (7658726), Teo, SH +999 morecore +1 more sourceThe tumor suppressor protein OPCML potentiates anti-EGFR and anti-HER2 targeted therapy in HER2-positive ovarian and breast cancer. [PDF]
, 2017 OPCML is a tumor suppressor gene that is frequently inactivated in ovarian cancer and many other cancers by somatic methylation. We have previously shown that OPCML exerts its suppressor function by negatively regulating a spectrum of receptor tyrosine ...Vaughan, S, Jane Antony, Karali, E, Imoh S. Okon, Justin Stebbing, Gabra, H, Arthur B. McKie, Antony, J, McKie, AB, Sebastian Vaughan, Zanini, E, Louay S. Louis, Evdoxia Karali, Mona El-Bahrawy, Louis, LS, Stebbing, J, El-Bahrawy, M, Okon, IS, Chiara Recchi, Hani Gabra, Recchi, C, Elisa Zanini +21 morecore +1 more sourceParaneoplastic thrombocytosis in ovarian cancer [PDF]
, 2012 <p>Background: The mechanisms of paraneoplastic thrombocytosis in ovarian cancer and the role that
platelets play in abetting cancer growth are unclear.</p>
<p>Methods: We analyzed clinical data on 619 patients with epithelial ...Han, H.D., Wang, R., Collins, K., Drew, A.F., Vasquez, H.G., Coward, J., Deavers, M.T., Urbauer, D., Lamkin, D., Matsuo, K., Sood, A.K., Stone, R.L., Lopez-Berestein, G., Bottsford-Miller, J., Shahzad, M.M.K., King, E.R., Mcneish, I.A., Afshar-Kharghan, V., Gershenson, H., Rupairmoole, R., Ahn, E.H., DeGeest, K., Gushiken, F., Tekedereli, I., Ozpolat, B., Nick, A.M., Chiu, W., Armaiz-Pena, G.N., Lutgendorf, S.K., Landen, C.N., Bond, V.K., Balkwill, F., Hu, W., Pecot, C.V. +33 morecore +1 more sourceThe anticancer effect of the HDAC inhibitor belinostat is enhanced by inhibitors of Bcl‐xL or Mcl‐1 in ovarian cancer
Molecular OncologyIdentifying innovative therapeutic strategies is crucial to improve clinical management of ovarian cancer. Previously, we showed that ovarian cancer cell apoptosis can be triggered by inhibiting the anti‐apoptotic proteins Bcl‐xL and Mcl‐1 and/or by ...Cécilia Thomine, Sterenn Guillemot, Louis‐Bastien Weiswald, Romane Florent, Edwige Abeilard, Florence Giffard, Emilie Brotin, Mélanie Briand, Enora Dolivet, Laurent Poulain, Marie Villedieu +10 moredoaj +1 more sourceOrganoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.Carla Ríos Arceo, Jarno Drostwiley +1 more sourceThe OVAREX study: Establishment of ex vivo ovarian cancer models to validate innovative therapies and to identify predictive biomarkers
BMC CancerBackground Ovarian cancer is the first cause of death from gynecological malignancies mainly due to development of chemoresistance. Despite the emergence of PARP inhibitors, which have revolutionized the therapeutic management of some of these ovarian ...Lucie Thorel, Jordane Divoux, Justine Lequesne, Guillaume Babin, Pierre-Marie Morice, Romane Florent, Guillaume Desmartin, Lucie Lecouflet, Chloé Marde Alagama, Alexandra Leconte, Bénédicte Clarisse, Mélanie Briand, Roman Rouzier, Léopold Gaichies, Sandrine Martin-Françoise, Jean-François Le Brun, Christophe Denoyelle, Nicolas Vigneron, Corinne Jeanne, Cécile Blanc-Fournier, Raphaël Leman, Dominique Vaur, Martin Figeac, Matthieu Meryet-Figuiere, Florence Joly, Louis-Bastien Weiswald, Laurent Poulain, Enora Dolivet +27 moredoaj +1 more source
