Results 161 to 170 of about 153,874 (301)

Beyond Extracellular Vesicle (EV) Hype: Practical Solutions and Remaining Hurdles in EV Research, Manufacturing, and Clinical Translation

Advanced Science, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are nanoscale mediators of intercellular communication with diverse molecular cargoes that reflect their cell of origin. Advances in isolation, detection, and single‐particle analytics have revealed increasing molecular and functional heterogeneity, while exposing limitations in how EV identity and activity are ...
David J. Lundy, Zoe L. Chau, Sheng‐You Chen, Nanami Fujisawa, John J. Hill, Barnett M. Hsu, Joanne K. Liu, Karol W. Mai, James J. Lai   +8 more
wiley   +1 more source

Physician-level variability in adopting opportunistic salpingectomy for ovarian cancer prevention at the time of hysterectomy. [PDF]

Int J Gynecol Cancer
Xu X, Desai VB, Gross CP, Spatz ES, Pollack CE, Wright JD.   +5 more
europepmc   +1 more source

One‐Step Glycoengineering of NK Cells With High‐Affinity Siglec Ligands for Cancer Immunotherapy

Advanced Science, EarlyView.
This study develops an engineered NmCSS enzyme with improved activity for bulky group modified sialic acids, enabling efficient synthesis of structurally diverse sialoside analogs in a single step. Glycan microarray screening identified Siglec high‐affinity ligands, which were incorporated onto natural killer (NK) cells via a one‐pot enzymatic system ...
Shuai Hu, Ben Huang, Lingyan Wang, Qiang Guo, Cuiping Jiang, Ruicheng Qi, Shuyao Wang, Lin‐Tai Da, Wenjie Peng   +8 more
wiley   +1 more source

Navigating dual risks: Ovarian cancer prevention and cardiovascular health in patients with hereditary cancer syndromes. [PDF]

Gynecol Oncol Rep
Keenahan L, Ahsan MD, Mecklai A, Frey MK.   +3 more
europepmc   +1 more source

Quantitative multispectral ex vivo optical evaluation of human ovarian tissue using spatial frequency domain imaging [PDF]

, 2018
Hagemann, Ian S, Nandy, Sreyankar, Powell, Matthew A, Siegel, Cary, Zhu, Quing   +4 more
core   +2 more sources

Sensing and Reprogramming Surface Receptor Activation With Synthetic Transcriptional Circuits

Advanced Science, EarlyView.
A synthetic receptor‐signalling induced transcription (RESIT) circuit is designed based on receptor activation mediated split protease complementation and release of membrane‐tethered synthetic transcriptional modules. The RESIT system enables probing Ca2+ entry, receptor tyrosine kinase (RTK) activities and Ras activation, and reprogramming RTK ...
Fei Liu, Mei Yuan, Li‐Juan Tang, Fenglin Wang, Xia Chu, Jian‐Hui Jiang   +5 more
wiley   +1 more source

The Role of Responsibility in Gynecological Oncology [PDF]

, 2003
Di Pietro, Maria Luisa, Sgreccia, Elio
core   +1 more source

Secondary Prevention of Ovarian Cancer

Abstract Cancer of uterine cervix and ovaries are the common female genital organ cancers. Cervical cancer is preventable primarily by vaccination and secondarily by treating pre-cancer lesions as the surrogate markers by programmatic screening methods.
openaire   +1 more source

Nanomedicine Meets Immunotherapy: Advancing Adoptive Cell Therapy with Nanoparticles in the Treatment of Cancer with Sustainability Perspectives

Advanced Science, EarlyView.
This review surveys nanoparticle‐based strategies to enhance adoptive cell therapy, particularly CAR‐T cell approaches, in solid tumor treatment. It describes how nanoparticles can improve tumor immunogenicity and T‐cell infiltration while reducing toxicity, and how they enable in vivo CAR‐T cell generation.
Erica Frostegård, Tatiana Bobrova, Amalie Leinebø, Thibault Leray, Shayamita Ghosh, Lorena García‐Hevia, Chiara Puccinelli, Lorenzo Riccio, Jacopo Sorani, Davide Bonifazi, Julien Caumartin, Emmanuel Donnadieu, Florence Gazeau, Roland Hischier, Else Marit Inderberg, Mónica L. Fanarraga, Maria Loustau, Bernd Nowack, Sébastien Wälchli, Cécilia Ménard‐Moyon   +19 more
wiley   +1 more source

Implementation of opportunistic salpingectomy for ovarian cancer prevention: Analyzing clinical practice and key characteristics. [PDF]

Acta Obstet Gynecol Scand
Fisch C, Gelderblom ME, Slangen B, Oei ALM, van Ginkel AA, Ngo H, de Hullu J, Piek J, Hermens R.   +8 more
europepmc   +1 more source