Results 211 to 220 of about 4,801,388 (251)

Fertility counseling and preservation considerations in patients with gynecologic and non‐gynecologic BRCA and Lynch‐associated malignancies

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Lynch syndrome and BRCA‐mutation associated malignancies are fortunately rare. Affected patients have an increased risk of cancer diagnosis at a young age, often significantly overlapping with their reproductive years. In helping these patients, oncologists must navigate the following areas of care: cancer prevention, impact of cancer ...
Anna Weimer, Nadeem Abu‐Rustum, David Mutch, Mauricio Cuello, Angélica Fletcher, Hextan Y. S. Ngan, Nozomu Yanaihara, Rene Pareja, Christina Fotopoulou, Kenneth Ruzindana, Ka Yu Tse, Yana Zou, Neerja Bhatla, Ting‐Chang Chang, Munanchiso Ndukwe Iheme Jr, Jalid Sehouli, Nicole Conchin, Eva Chalas, Sarikapan Wilailak, Barbara Schmalfeldt, Alexander B. Olawaiye   +20 more
wiley   +1 more source

Brazilian Society of Surgical Oncology Analysis in Cost-Effectiveness of Population-Based BRCA Testing for Ovarian Cancer in the Public Health System. [PDF]

J Surg Oncol
Oliveira AF, de Santa Rosa AAP, Tsunoda AT, Azevedo BRB, de Carvalho EM, Baiocchi G, Lyra JS, de Sousa Fernandes PH, Zanatto RM, Ribeiro R, da Costa Vieira RA, de Lorena Medeiros RC, Pinheiro RN, Reis RJ, Carneiro VCG, Oliveira VRE.   +15 more
europepmc   +1 more source

Long‐Read Pan‐Cancer Transcriptomics Unravel Distinct Alteration Trends Between Gene and Isoform Expression in Tumorigenesis

iMetaMed, EarlyView.
Long‐read profiling of 144 tumor‐normal pairs identifies isoform‐level cancer dysregulation independent of gene changes. Our scoring system prioritizes isoform‐driven prognostic genes across cancers. ABSTRACT Tumorigenesis involves transcriptomic alterations at both gene and isoform levels.
Yuying Ding, Bo Wu, Dan Zhou, Qiang Li, Dingru Li, Mengyun Cai, Zhiyan Chen, Caimei Zhong, ChuanLe Xiao, Yuhua Deng   +9 more
wiley   +1 more source

Fertility preservation and reproductive outcomes in young women with breast and gynecological cancers: a new challenge for the clinician. [PDF]

Front Oncol
Santangelo G, Tonti N, Lamorgese L, Golia D'Augé T, Palaia I, Tomao F, Di Donato V, Perniola G, Muzii L.   +8 more
europepmc   +1 more source

Lactobacillus johnsonii attenuates ovarian aging by remodeling the gut–ovary axis

iMetaOmics, EarlyView.
Aging is accompanied by a reduced abundance of L. johnsonii and ovarian decline. Supplementation with L. johnsonii elevates microbial IPA production via the LdhA enzyme and commensal bacteria. IPA activates the AhR/YAP signaling axis, promoting YAP nuclear translocation and inducing the expression of downstream target genes CYR61 and CTGF. This cascade
Jiamin He, Qiwen Wang, Luyi Chen, Yadong Qi, Dingjiacheng Jia, Jilei Xu, Qingyi Wang, Yao Jiang, Jian Zhou, Yong Sun, Ruochen Yan, Lan Wang, Tongyao Hou, Zheng Kuang, Min Jin, Liangjing Wang, Shujie Chen   +16 more
wiley   +1 more source

Menopause following cancer treatment-induced menopause: unique considerations and current recommendations. [PDF]

Reprod Fertil
Yongue G, Nash Z, Manley K, Davies MC, Nicum S.   +4 more
europepmc   +1 more source

Frontiers in transition‐metal single‐atom electrocatalysts: Design tactics, mechanistic regulation, and electrochemical sensing technologies

InfoMat, EarlyView.
This review offers an overview of recent advances in the fundamental properties, synthesis methods, and structural optimization of transition‐metal single‐atom electrocatalysts for electrochemical sensing. It also provides a comprehensive summary of the emerging applications in electrochemical assays based on these materials, along with key challenges ...
Yue Cao, Bo‐Yu Chen, Yiru Sheng, Haoyuan Song, Linan Zhu, Xiaohan Yang, Yuehe Lin, Wenlei Zhu, Yang Zhou   +8 more
wiley   +1 more source

Recent Developments in Studies on the Relation Between Endometriosis and Ovarian Cancer: Phenotype-Specific Risk, Molecular Convergence and Clinical Risk Stratification. [PDF]

Cancers (Basel)
Gutowska K, Urban A, Wojtyła C, Ławicki S, Laudański P.   +4 more
europepmc   +1 more source

The T‐Cell Response Mechanism in Human Papillomavirus‐Associated Cervical Cancer and New Strategies for Immunotherapy

iNew Medicine, EarlyView.
ABSTRACT Human papillomavirus (HPV) is a double‐stranded DNA virus that infects human skin and mucosal tissues exclusively. The German scientist Harald zur Hausen was awarded the 2008 Nobel Prize in Physiology or Medicine for his discovery of the link between HPV infection and cervical cancer.
Fang Zhu, Farah Nazir, Ying Zhou, Yuhua Shang, Hongliang He, Tengchuan Jin   +5 more
wiley   +1 more source

Higher dietary phytochemical index is associated with lower risk of epithelial ovarian cancer in Chinese women: a case-control study. [PDF]

Front Nutr
Yang Y, Zhang R, Zhu M, Zu Y.
europepmc   +1 more source