Results 11 to 20 of about 281,298 (260)

Carcinoma of Ovarian Teratoma [PDF]

open access: yesThe American Journal of the Medical Sciences, 1920
n ...
Clark, John G., Block, Frank B.
openaire   +2 more sources

Epigenomics and Ovarian Carcinoma [PDF]

open access: yesBiomarkers in Medicine, 2010
Ovarian cancer is the leading cause of death among gynecological cancers. It is now recognized that in addition to genetic alterations, epigenetic mechanisms, such as DNA methylation, histone modifications and nucleosome remodeling, play an important role in the development and progression of ovarian cancer by modulating chromatin structure, and gene ...
Leonel, Maldonado   +1 more
openaire   +2 more sources

Purinergic Signaling in Ovarian Carcinoma. [PDF]

open access: yesAdv Pharm Bull
Ovarian carcinoma (OC) is the most lethal gynecological cancer worldwide. Around 95% of patients exhibit recurrence five years after treatment; 80% experience recurrence within 18 months after first-line treatment, and progression-free survival rates have not changed over the past 40 years. New therapeutic approaches are imperative to face this complex
Martínez-Ramírez AS   +4 more
europepmc   +4 more sources

RDM1 plays an oncogenic role in human ovarian carcinoma cells

open access: yesArtificial Cells, Nanomedicine, and Biotechnology, 2020
Ovarian cancer is one of the deadliest gynecological cancer, with a low overall 5-year survival rate. RDM1, RAD52 motif-containing protein 1, is sensitive to cisplatin, a common chemotherapy drug and it has an important role inDNA damage repair pathway ...
Lu Tong   +7 more
doaj   +1 more source

MicroRNAs in ovarian carcinomas [PDF]

open access: yesEndocrine-Related Cancer, 2010
The molecular mechanisms involved in epithelial ovarian cancer initiation and progression are just beginning to be elucidated. In particular, it has become evident that microRNAs (miRNAs or miRs), a class of molecules that post-transcriptionally regulate gene expression, play a major role in ovarian tumorigenesis.
Neetu, Dahiya, Patrice J, Morin
openaire   +2 more sources

Familial Ovarian Carcinoma

open access: yesUpsala Journal of Medical Sciences, 1976
Familial aggregation of patients with ovarian carcinoma is unusual. A family with four affected members in three consecutive generations is described. The tumors were all of the serous papillary adenocarcinoma type. The pattern of appearance of the malignant disorder in the present family may be explained as the result of transmission of a dominant ...
L, Thor, B H, Persson, B, Kjessler
openaire   +2 more sources

Combined PD-1/PD-L1 and tumor-infiltrating immune cells redefined a unique molecular subtype of high-grade serous ovarian carcinoma

open access: yesBMC Genomics, 2022
Background High-grade serous ovarian carcinoma is highly heterogeneous, and although many studies have been conducted to identify high-grade serous ovarian carcinoma molecular subtypes that are sensitive to immunotherapy, no precise molecular subtype has
Ping Liu   +5 more
doaj   +1 more source

Carbonic anhydrase XII as biomarker and therapeutic target in ovarian carcinomas.

open access: yesPLoS ONE, 2022
Targeting the tumor-associated carbonic anhydrase XII (CA XII) is considered a promising strategy to improve cancer treatment. As such progress is highly demanded for ovarian carcinomas, the present study aimed to provide deeper information about their ...
Lisa Hiepp   +8 more
doaj   +1 more source

Pathobiology of ovarian carcinomas

open access: yesChinese Journal of Cancer, 2015
Ovarian tumors comprise a heterogeneous group of lesions, displaying distinct tumor pathology and oncogenic potentiel. These tumors are subdivided into three main categories: epithelial, germ cell, and sex-cord stromal tumors. We report herein the newly described molecular abnormalities in epithelial ovarian cancers (carcinomas).
Devouassoux-Shisheboran, Mojgan   +1 more
openaire   +2 more sources

The Expression and Significance of Dickkopf-1 in Epithelial Ovarian Carcinoma

open access: yesThe International Journal of Biological Markers, 2009
The aim of this study was to investigate the presence and prognostic value of Dickkopf-1 (DKK1) in epithelial ovarian carcinoma. The expression of DKK1 was determined in 56 epithelial ovarian carcinoma tissues, 35 benign ovarian cystadenoma tissues, and ...
Wang Shizhuo   +3 more
doaj   +1 more source

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