Results 21 to 30 of about 281,298 (260)

Vaccines for Ovarian Carcinoma

Cancer Control, 1999
Background Metastasis to the abdominal cavity is the primary cause of morbidity and mortality in patients with ovarian cancer. Beyond surgery and chemotherapy combinations, strategies that target tumor cells in vivo are being investigated, such as the use of recombinant cytokines to up-regulate or modulate the ...
Cherie Butts, Ralph S. Freedman
openaire   +2 more sources

C-reactive protein as a diagnostic marker for ovarian carcinoma

Italian Journal of Medicine
Ovarian carcinoma is a leading cause of death in gynecological cancers, making early detection crucial for improving survival rates. C-reactive protein (CRP) has shown promise as a cost-effective biomarker to distinguish ovarian carcinoma from benign ...
Angga Dewi Umar Wahyu, Syahrul Rauf, Susiawaty Susiawaty, Maisuri T. Chalid, Nugraha Utama Pelupessy, Irma Savitri   +5 more
doaj   +1 more source

The anti-tumor effects and molecular mechanisms of suberoylanilide hydroxamic acid (SAHA) on the aggressive phenotypes of ovarian carcinoma cells. [PDF]

PLoS ONE, 2013
Histone deacetylase inhibitors (HDACi), such as suberoylanilide hydroxamic acid (SAHA), have been shown to act selectively on gene expression, and are potent inducers of growth arrest, differentiation and apoptosis in various types of cancers in vitro ...
Shuo Chen, Yang Zhao, Wen-feng Gou, Shuang Zhao, Yasuo Takano, Hua-chuan Zheng   +5 more
doaj   +1 more source

A rare case of ovarian carcinosarcoma with squamous cell carcinoma

Journal of Ovarian Research, 2019
Background Ovarian carcinosarcoma, which contains sarcomatous and carcinomatous components, is a very rare tumor. The carcinomatous component is often adenocarcinoma, and squamous cell carcinoma is extremely rare.
Atsushi Daimon, Satoe Fujiwara, Yoshimichi Tanaka, Tomohito Tanaka, Masahide Ohmichi   +4 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

The Significance of p53 Immunostaining in Various Surface Epithelial Carcinomas of The Ovary

Minia Journal of Medical Research
Background: Ovarian Carcinoma (OC) is the 8th most prevalent cancer incidence among women globally. Its pathogenesis is not well understood till now. p53 is commonly mutated in human malignancies and has been a prominent subject of investigation in the ...
Mina Attya, zahraa khalil, nesreen osman, Eman Mohamed   +3 more
doaj   +1 more source

Overexpression of EFEMP1 correlates with tumor progression and poor prognosis in human ovarian carcinoma. [PDF]

PLoS ONE, 2013
OBJECTIVE:This study was to explore the role of EFEMP1 in ovarian tumor progression and its relationship with prognosis of ovarian carcinoma. METHODS:EFEMP1 mRNA and protein expressions in normal ovarian tissue, ovarian tumor, high invasive subclones and
Jie Chen, Deying Wei, Yueran Zhao, Xiaoyan Liu, Jie Zhang   +4 more
doaj   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Computed Tomography of Ovarian Carcinoma

Acta Radiologica. Diagnosis, 1984
Forty-seven patients with ovarian carcinoma were examined with computed tomography (CT). Fourteen were evaluated before laparotomy (group I), 25 following surgical treatment (group II), and 8 were followed by CT in the course, or following chemotherapy with or without radiation therapy (group III).
Kalovidouris, A., Gouliamos, A., Pontifex, Gr., Gennatas, K., Dardoufas, K., Papavasiliou, C.   +5 more
openaire   +3 more sources