Results 81 to 90 of about 10,574,592 (282)

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

FEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang, Mingqiang Deng, Dongmei He, Diqin Lai, Dongjun Liu, Dengyong Zhu, Zhenhua Zhang, Peng Tang, Chuanman Zhou, Menghui Yin, Xichen Bao   +10 more
wiley   +1 more source

Grip Margin-Based Control Allocation for Enhanced Vehicle Stability in Four-Wheel Independent Steering Vehicle

IEEE Access
This study aims to enhance the control performance of four-wheel independent steering vehicles (4WIS), which are increasingly recognized as a key innovation in electric vehicle technology. 4WIS provides a high degree of freedom and dynamic performance by
Gyu-Yong Hwang, Chulhee Han, Min-Sang Seong, Dongwook Lee, Jong-Seok Oh   +4 more
doaj   +1 more source

Dynamic Model and Control of an Over-actuated Quadrotor UAV

, 2012
In this paper, a novel omnidirectional unmanned flying vehicle (UAV) is presented. Staring from the well known quadrotor model, some features has been introduced in order to create an over-actuated quadrotor able to fly performing maneuvers that are ...
MELCHIORRI, CLAUDIO, FALCONI, RICCARDO
core   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

FEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo, Kátia Cristiane Hall, Matheus dos Santos Fernandez, Geovanna Peter Corrêa, Rafael Guerra Lund   +4 more
wiley   +1 more source

Low cost integration of Electric Power-Assisted Steering (EPAS) with Enhanced Stability Program (ESP) [PDF]

, 2014
Vehicle Dynamics Control (VDC) systems (also known as Active Chassis systems) are mechatronic systems developed for improving vehicle comfort, handling and/or stability.
Soltani, Amirmasoud
core   +3 more sources

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Transient response and frequency domain analysis of an electrically variable transmission

Advances in Mechanical Engineering, 2018
This article deals with the dynamic behavior of a passenger car equipped with an electrically variable transmission, which is analyzed both in time and frequency domains.
Enrico Galvagno, Alessandro Vigliani, Mauro Velardocchia   +2 more
doaj   +1 more source

Path-tracking control at the limits of handling of a prototype over-actuated autonomous vehicle [PDF]

Considering the vehicle dynamics at the limits of handling is vital to improve the performance and safety of autonomous vehicles especially in extreme situations.
Velenis, Efstathios, Siampis, Efstathios, Lin, Chenhui   +2 more
core   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

Lyapunov based trajectory tracking controller for a quadrotor UAV with nonholonomic constraints

e-Prime: Advances in Electrical Engineering, Electronics and Energy
This paper presents a Lyapunov based controller for a quadrotor Unmanned Aerial Vehicle (UAV) to address the desired trajectory tracking problem. The controller is designed based on the dynamical model of the quadrotor UAV.
Arindam Singha, Sanjay Thakur, Anjan Kumar Ray   +2 more
doaj   +1 more source