Results 51 to 60 of about 259,578 (273)

Quercetin Suppresses the Progression of Atherosclerosis by Regulating MST1-Mediated Autophagy in ox-LDL-Induced RAW264.7 Macrophage Foam Cells

open access: yesInternational Journal of Molecular Sciences, 2019
Objective: To investigate the process by which quercetin suppresses atherosclerosis by upregulating MST1-mediated autophagy in RAW264.7 macrophages. Methods: An in vitro foam cell model was established by culturing RAW264.7 macrophages with oxidized low ...
Hui Cao   +5 more
semanticscholar   +1 more source

AEE alleviates ox-LDL-induced lipid accumulation and inflammation in macrophages

open access: yesBiomedicine & Pharmacotherapy, 2023
Atherosclerosis is a chronic immune inflammatory disease. Aspirin eugenol ester (AEE) is a novel safe and non-toxic compound with many pharmacological effects such as anti-inflammatory, anti-hyperlipidemic and anti-thrombotic action. In order to investigate the effect of AEE on the inhibition of aortic lipid plaque formation and macrophage-derived foam
Ya-Xian, Liu   +9 more
openaire   +2 more sources

Oxidized low density lipoprotein leads to macrophage accumulation of unesterified cholesterol as a result of lysosomal trapping of the lipoprotein hydrolyzed cholesteryl ester.

open access: yesJournal of Lipid Research, 1994
The early atherosclerotic lesion is comprised of foam cell macrophages filled with cholesteryl ester (CE), unesterified cholesterol (UC), and cholesterol oxides.
I Maor, M Aviram
doaj   +1 more source

Diabetic dyslipidaemia is associated with alterations in eNOS, caveolin-1 and endothelial dysfunction in streptozotocin treated rats [PDF]

open access: yes, 2018
This is the peer reviewed version of the following article: Yousif A. Shamsaldeen, Rosemary Ugur, Christopher D. Benham, and Lisa A. Lione, ‘Diabetic dyslipidaemia is associated with alterations in eNOS, caveolin‐1, and endothelial dysfunction in ...
Amalan   +31 more
core   +2 more sources

Endothelial cells, endoplasmic reticulum stress and oxysterols [PDF]

open access: yes, 2017
Oxysterols are bioactive lipids that act as regulators of lipid metabolism, inflammation, cell viability and are involved in several diseases, including atherosclerosis.
Canonico, B.   +10 more
core   +3 more sources

Oxidized Low-Density Lipoprotein Serum Concentrations and Cardiovascular Morbidity in End Stage of Renal Disease

open access: yesJournal of Cardiovascular Development and Disease, 2018
Introduction: Oxidized low-density lipoprotein (ox-LDL) is considered a main biomarker of oxidative stress, a common characteristic in end stage renal disease. We examined the relationship between ox-LDL serum concentrations and cardiovascular disease in
Vaia Raikou   +2 more
doaj   +1 more source

A study on oxidized-LDL cholesterol in normolipidemic retinal vein occlusion

open access: yesAsian Journal of Medical Sciences, 2023
Background: Oxidized low-density lipoprotein (ox-LDL) has been implicated in atherosclerotic cardiovascular disease. Arteriolosclerosis is an important causative factor for retinal vein occlusion (RVO).
Kapil Deb Lahiri   +2 more
doaj   +1 more source

The Relationship of Plasma miR-29a and Oxidized Low Density Lipoprotein with Atherosclerosis

open access: yesCellular Physiology and Biochemistry, 2016
Background/Aims: Atherosclerosis is a chronic inflammatory condition associated with a variety of vascular diseases. Previous studies showed that both miR-29a and oxidized low density lipoprotein (ox-LDL) were vital in the development of atherosclerosis.
Yu-Qing Huang   +5 more
doaj   +1 more source

LncRNA ZEB1-AS1 knockdown alleviates oxidative low-density lipoprotein-induced endothelial cell injury via the miR-590-5p/ HDAC9 axis

open access: yesCentral European Journal of Immunology, 2021
Oxidative low-density lipoprotein (ox-LDL) is thought to induce vascular endothelial cell injury, which contributes to the aetiopathogenesis of atherosclerosis (AS).
Jinpeng Zhong   +7 more
doaj   +1 more source

Human Monocytes/Macrophages Release TNF-α in Response to Ox-LDL [PDF]

open access: yesArteriosclerosis, Thrombosis, and Vascular Biology, 1996
The uptake of oxidatively modified low density lipoprotein (Ox-LDL) by intimal macrophages is believed to play a key role in the development of atherosclerosis. The present study demonstrates that Ox-LDL in low concentrations activates monocyte/macrophage release of factors that stimulate smooth muscle cell growth, whereas higher concentrations are ...
S, Jovinge   +3 more
openaire   +2 more sources

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