Results 121 to 130 of about 25,633 (260)

Design, synthesis, and enzyme kinetic evaluation of oxadiazole derivatives as nucleoside triphosphate diphosphohydrolase (NTPDase) inhibitors: an integrated <i>in vitro</i> and <i>in silico</i> approach. [PDF]

RSC Adv
Abbas SZ, Ashraf Z, Roshan S, Sughra K, Rahat MA, Shakir I, Latif M.   +6 more
europepmc   +1 more source

Synthesis and Characterization of 1, 3, 4-Oxadiazole Derivatives

, 2019
1,3,4-oxadiazole is a five member heterocyclic ring which is a very important compound for designing potent bioactive agents. This interesting group of compound has different biological activities such as anti-inflammatory, antimicrobial, anticancer ...
Gupta, M.K., Singhai, Anuj
core  

Design, synthesis, enzymatic and <i>in vivo</i> antihyperglycemic activity evaluation of 1,3,4-oxadiazole derivatives targeting multiple pathways in type 2 diabetes. [PDF]

RSC Adv
Shereen, Tahir A, Ahmed A, Jan MS, Aslam N, Hassan S, Rashid U.   +6 more
europepmc   +1 more source

VARIOUS BIOLOGICAL ACTIVITIES OF COUMARIN AND OXADIAZOLE DERIVATIVES

, 2017
In this review article data is collected regarding the various derivatives of coumarin and oxadiazole as both these have wide range of biological activities and they can be further modified to synthesize more effective and potent drugs. Coumarin class of
Saini, Rupinder, Sethi, Navdeep Singh, Jalhan, Sunny, Singh, Sukhdev, Jain, Upendra K   +4 more
core  

1,3,4-Oxadiazole derivatives: targeting multiple bacterial pathways. [PDF]

RSC Med Chem
Gupta P, Verma S, Narang R, Sharma B, Singh V, Lal S.   +5 more
europepmc   +1 more source

Multifunctional pectin derivatives as anticancer agents in colorectal cancer via synthesis, computational insights, and modulation of NRF2/HO-1, HIF-1α, and VEGF/PDGF-D signaling pathways. [PDF]

Sci Rep
Elsayed GH, Fahim AM.
europepmc   +1 more source

Benzo[<i>d</i>]imidazole anchored oxadiazole derivatives: synthesis, characterization, biological evaluation, <i>in silico</i> docking and ADME-T analysis. [PDF]

RSC Adv
Salluri YR, Chepuri K, Anwar S.
europepmc   +1 more source

Synthesis and Synthetic Applications of 1,2,4-Oxadiazole-4-Oxides

, 2007
The first 1,2,4-oxadiazole-4-oxide was prepared by Wieland a century ago, but-this compound remained largely a chemical curiosity until very recently.
CARAMELLA, PIERLUIGI, QUADRELLI, PAOLO
core  

Design, Synthesis and Biological Evaluation of Oxadiazole-Biphenyl Derivatives as Small Molecule Inhibitors Targeting PD-1/PD-L1 Immune Checkpoint. [PDF]

ACS Med Chem Lett
Xie L, Zhu M, Zhao T, Pei Y, Wei B, Zhu S, Chen J, Zhang H, Zhou J.   +8 more
europepmc   +1 more source

Experimental and MEDT Study of Sydnone-Alkyne Cycloaddition-Based Synthesis of 1,4-Disubstituted Pyrazoles and In Silico Investigation of Their Binding to HCV and HIV Proteins. [PDF]

Molecules
Zerbib S, Eddahmi M, Alaqarbeh M, Bodet PE, Thiery V, Fatimi A, Cruz-Martins N, Bailly C, Domingo LR, Bouissane L.   +9 more
europepmc   +1 more source