Results 231 to 240 of about 41,732 (296)

Unlocking the potential of mandelic acid derivatives: chemical and biological applications - a comprehensive review. [PDF]

RSC Adv
Banerjee A, Mitra AK.
europepmc   +1 more source

Synthesis and Structural Study of Some Mo(II)Carbonyl Complexes with Triazole and Oxadiazole Derivatives

, 2009
Sh. M. H. Obed
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Rational design of lanthanide-based metal-organic frameworks for CO₂ capture using computational modeling.

Mater Adv
Haslak ZP, Gulbalkan HC, Keskin S.
europepmc   +1 more source

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Bioisosterism: 1,2,4‐Oxadiazole Rings

ChemMedChem, 2023
AbstractAlthough studies in drug discovery have gained momentum in recent years, the conversion of drugs in use today into less toxic derivatives with pharmacologically superior properties is still of great importance in drug research. Bioisosterism facilitates the conversion of drugs into derivatives that present more positive pharmacological and ...
Merve Camci, Nilgün Karali
openaire   +3 more sources

Selective and Bioavailable HDAC6 2-(Difluoromethyl)-1,3,4-oxadiazole Substrate Inhibitors and Modeling of Their Bioactivation Mechanism.

Journal of Medicinal Chemistry, 2023
Histone deacetylase 6 (HDAC6) is a unique member of the HDAC family mainly targeting cytosolic nonhistone substrates, such as α-tubulin, cortactin, and heat shock protein 90 to regulate cell proliferation, metastasis, invasion, and mitosis in tumors.
L. Ripa, Jenny Sandmark, Glyn Hughes, Igor Shamovsky, Anders Gunnarsson, Julia Johansson, A. Llinàs, Mia Collins, Bomi Jung, Anna Novén, Nils Pemberton, M. Mogemark, Yao Xiong, Qing Li, Stefan Tångefjord, M. Ek, Annika Åstrand   +16 more
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Transformation of Covalent Organic Frameworks from N-Acylhydrazone to Oxadiazole Linkages for Smooth Electron Transfer in Photocatalysis.

Angewandte Chemie, 2021
Covalent organic frameworks (COFs) are regarded as new platforms for solar-to-chemical energy conversion due to their tailor-made functions and pre-designable structures.
Ruihu Wang, Shuailong Yang, Haowei Lv, Hong Zhong, Daqiang Yuan, Xinchen Wang   +5 more
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Oxadiazole: A highly versatile scaffold in drug discovery

Archiv der Pharmazie, 2022
As a pharmacologically important heterocycle, oxadiazole paved the way to combat the problem associated with the confluence of many commercially available drugs with different pharmacological profiles.
N. Desai, Jahnvi D. Monapara, Aratiba M. Jethawa, V. Khedkar, B. Shingate   +4 more
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Unique Carbazole-Oxadiazole Derivatives as New Potential Antibiotics for Combating Gram-Positive and -Negative Bacteria.

Journal of Medicinal Chemistry, 2022
Novel carbazole-oxadiazoles were developed as new potential antibacterial agents to combat dreadful resistance. Some target compounds displayed predominant inhibitory effects on the tested Gram-positive and -negative bacteria, and carbazole-oxadiazoles ...
Yun-Peng Xie, Nagarajan Sangaraiah, J. Meng, Cheng‐He Zhou   +3 more
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