Results 151 to 160 of about 62,929 (228)

Safety and Efficacy of a Sandwich Total Neoadjuvant Therapy Strategy for Low‐Risk Distal Locally Advanced Rectal Cancer: Results From the TESS Phase II Trial

MedComm, Volume 7, Issue 7, July 2026.
The proposed sandwich total neoadjuvant treatment (TNT) strategy (NeoCT–CRT–NeoCT) represents a safe and effective therapeutic option for carefully selected patients with low‐risk distal locally advanced rectal cancer (LARC). By sequentially integrating induction chemotherapy, concurrent chemoradiotherapy, and consolidation chemotherapy, this approach ...
Shuang Liu, GuangZhao Lv, GeYu Xu, XiaoZhong Wang, YeZhong Zhuang, ShouMin Bai, HaiNa Yu, XiaoJun Wu, YiJing Ye, HuiLong Luo, ShuoYu Xu, QiaoXuan Wang, Hui Chang, PeiQiang Cai, ZhiZhong Pan, YuanHong Gao, Gong Chen, WeiWei Xiao   +17 more
wiley   +1 more source

Statement of Retraction: WD repeat domain 62 (WDR62) promotes resistance of colorectal cancer to oxaliplatin through modulating mitogen-activated protein kinase (MAPK) signaling. [PDF]

Bioengineered
europepmc   +1 more source

RNA Modifications in Tumor Microenvironment: A New Dimension for Cancer Treatment

MedComm, Volume 7, Issue 7, July 2026.
Tumor initiation and progression depend on a supportive and highly heterogeneous tumor microenvironment (TME). RNA modifications regulate signaling pathways and cytokine networks that shape TME dynamics, facilitating interactions between cancer cells and noncancerous stromal cells, and ultimately promoting immune evasion and tumor progression ...
Qiwen Li, Yating Sun, Shuibin Lin, Quan Yuan   +3 more
wiley   +1 more source

miR-100-5p Enhances Cell Cycle-Mediated Chemoresistance by Modulating the CTDSPL/pRB/E2F1 Signaling Pathway in Oxaliplatin-Resistant Colorectal Cancer Cells. [PDF]

Oncol Res
Chen YP, Baskaran R, Devi HS, Singh CH, Lin YJ, Shibu MA, Kuo WW, Liao SC, Chen MC, Wang TF, Li CC, Ho TJ, Shih TC, Lin SZ, Huang CY.   +14 more
europepmc   +1 more source

Intratumoral Microbiota in Tumor: Current Understandings and Future Perspectives

MedComm, Volume 7, Issue 7, July 2026.
Intratumoral bacteria are emerging as active regulators of cancer evolution rather than bystanders. This review outlines how tumor‐resident microbes drive tumor initiation and growth by inducing genomic instability, epigenetic reprogramming, oncogenic signaling, and chronic inflammation, while promoting metastatic spread via invasion, angiogenesis ...
Jiawei Chen, Yupan Bai, Lu Shen, Jiacheng Ying, Jie Xu, Jiayin Tang, Yujie Bao   +6 more
wiley   +1 more source

Phase II study of maintenance trifluridine/tipiracil (TAS-102) plus bevacizumab after induction chemotherapy in metastatic colorectal cancer. [PDF]

Oncologist
Ota K, Uemura M, Tanida T, Nakata K, Kudo T, Kagawa Y, Haraguchi N, Minami S, Matsuura Y, Ota H, Hiraki M, Yasui M, Takahashi H, Iwamoto K, Nishida N, Hata T, Nishizawa Y, Fukunaga M, Komori T, Takahashi Y, Tokuyama S, Tamagawa H, Naito A, Yoshihara T, Suzuki R, Sugimoto S, Miyake M, Takiguchi N, Tei M, Tamai K, Fukada A, Ogino T, Miyoshi N, Satoh T, Yamamoto H, Murata K, Doki Y, Eguchi H.   +37 more
europepmc   +1 more source

Dynamics of Circulating Tumor DNA (ctDNA) Predict Treatment Efficacy and Prognosis in Patients With Advanced Pancreatic Cancer: A Prospective Large‐Cohort Study

MedComm, Volume 7, Issue 7, July 2026.
A total of 127 advanced pancreatic ductal adenocarcinoma (PDAC) patients receiving first‐line therapy were enrolled in this study. A series of peripheral blood collected before the initiation of treatment (B1), at the first response assessment (B2), and at subsequent timepoints to perform high‐depth next‐generation sequencing.
Tingting You, Hui Tang, Mingming Yuan, Dongfeng Song, Chenyu Wang, Jinrong Ying, Rongrong Chen, Chunmei Bai, Yuejuan Cheng, Yingyi Wang   +9 more
wiley   +1 more source

Copy number alteration fingerprint predicts the clinical response of oxaliplatin-based chemotherapy in metastatic colorectal cancer. [PDF]

NPJ Precis Oncol
Weng J, Wang J, Tao Z, Wu T, Diao K, Wang J, Wang N, Ye Z, Zhang R, Shen J, Zhao X, Li X, Li X, Liu XS.   +13 more
europepmc   +1 more source

Diagnostic Impact of Liver Biopsy Among Antinuclear Antibody Positive Individuals With Mild Liver Enzyme Elevation

Alimentary Pharmacology &Therapeutics, Volume 64, Issue 1, Page 103-111, July 2026.
In ANA‐positive patients with suspected autoimmune hepatitis (AIH), liver biopsy rarely altered therapeutic management when alanine aminotransferase (ALT) was below 101 U/L and cirrhosis was absent. These findings suggest that biopsy may be safely deferred in this low‐risk group.
David Mehdi Asgher Niazi, Alphonse Charbel, Jan Pfeiffenberger, Uta Merle, Jessica Seessle, Theresa Wenz, Christa Flechtenmacher, Patrick Michl, Conrad Rauber   +8 more
wiley   +1 more source

A next-generation multimetal complex induces immunogenic cell death with distinct transcriptomic signatures.

Chem Commun (Camb)
Babu T, Levine MS, Zeng B, Sessler JL.
europepmc   +1 more source