Results 151 to 160 of about 63,127 (238)

A Catalytic Osmium Redox Couple Collapses Cancer Redox Balance

Advanced Science, Volume 13, Issue 43, 3 August 2026.
A stable Os(III)/Os(IV) redox couple is developed to disrupt the tumor cell redox balance by concurrently catalyzing ROS generation and GSH depletion. Osmium‐treated cells exhibit multiple cell death pathways, including apoptosis, ferroptosis, and immunogenic cell death.
Wan‐Qiong Huang, Tao Huang, Yiming Hao, Gui‐Feng Huang, Yi‐Lang Yan, Xin Fang, Ying Chen, Xiao‐Long Wei, Wai‐Lun Man, Wen‐Xiu Ni   +9 more
wiley   +1 more source

The role of NAD⁺ metabolic reprogramming in colorectal cancer chemoresistance: mechanistic insights, clinical translation challenges and opportunities. [PDF]

Front Oncol
Ma Z, Gong X, Liu F.
europepmc   +1 more source

PANX2 Suppresses Lung Adenocarcinoma Progression by Inducing Disulfidptosis and Enhancing Antitumor Immunity

Advanced Science, Volume 13, Issue 44, 7 August 2026.
ABSTRACT Lung adenocarcinoma (LUAD) remains a leading cause of cancer mortality with limited therapeutic options. Disulfidptosis, a novel cell death modality driven by disulfide stress, represents a promising target, yet its regulation in LUAD is poorly defined. Here, we identify Pannexin 2 (PANX2) as a tumor suppressor in LUAD.
Yi Chen, Zhao‐Yu Liu, Gao‐Wen Qu, Run‐Hao Zeng, Wen‐Xia Yao, Yong‐Bing Zhou, Xue Liang, Yu‐Xiong Lai   +7 more
wiley   +1 more source

Therapeutic Applications of Stimuli‐Based Release and Engineering of Extracellular Vesicles

Advanced NanoBiomed Research, Volume 6, Issue 8, August 2026.
This review summarizes the effects of endogenous and exogenous stimuli, their effects on the natural release of extracellular vesicles, as well as their uptake and release. It also gives an overview of stimuli‐responsive EVs and their therapeutic applications. Extracellular vesicles (EVs), nano‐ to microsized lipid bilayer membrane‐bound particles, are
Gloria Kemunto, Kristen Dellinger
wiley   +1 more source

Statement of Retraction: WD repeat domain 62 (WDR62) promotes resistance of colorectal cancer to oxaliplatin through modulating mitogen-activated protein kinase (MAPK) signaling. [PDF]

Bioengineered
europepmc   +1 more source

FAP-Anchored Retinoic Acid Nanoparticles for Stromal Reprogramming and Enhanced Intratumoral Oxaliplatin Delivery in Fibrotic Colorectal Tumours. [PDF]

Biosensors (Basel)
Wang H, Xu C, Xie L, Chu X, Liu X, Wang P.   +5 more
europepmc   +1 more source

Assessing the Feasibility of a Self‐Management Intervention for Individuals With Advanced Prostate Cancer and Comorbid Type II Diabetes Mellitus

Cancer Medicine, Volume 15, Issue 8, August 2026.
ABSTRACT Background Many older adults with cancer have at least one comorbidity. Type II diabetes mellitus (T2DM) is a common comorbidity among patients with prostate cancer (PC) and represents an important consideration in this population. Comorbid T2DM can negatively impact cancer‐specific outcomes for patients, suggesting the need for better ...
Amy L. Shaver, Christina Steinbock‐Malfer, William Tester, Patrick Mille, William K. Kelly, Kevin K. Zarrabi, Costas D. Lallas, Mihir Shah, Rose DiMarco, Emily Brand, Shawntel Brown, Swapnil Sharma, Nikita Nikita, Cindy Cogen, Scott W. Keith, Grace Lu‐Yao   +15 more
wiley   +1 more source

miR-100-5p Enhances Cell Cycle-Mediated Chemoresistance by Modulating the CTDSPL/pRB/E2F1 Signaling Pathway in Oxaliplatin-Resistant Colorectal Cancer Cells. [PDF]

Oncol Res
Chen YP, Baskaran R, Devi HS, Singh CH, Lin YJ, Shibu MA, Kuo WW, Liao SC, Chen MC, Wang TF, Li CC, Ho TJ, Shih TC, Lin SZ, Huang CY.   +14 more
europepmc   +1 more source

Impact of Bone Marrow Involvement on the Success of Hematopoietic Stem Cell Mobilization in Patients With Lymphoma

Cancer Medicine, Volume 15, Issue 8, August 2026.
ABSTRACT The influence of bone marrow (BM) involvement at diagnosis on hematopoietic stem cell (HSC) mobilization outcomes remains to be fully elucidated, particularly in the contemporary plerixafor era. To address this issue, this multicenter retrospective cohort study including four lymphoma treatment centers evaluated patients who underwent their ...
Jie Lv, Zailin Yang, Xiaoqian Liu, Yao Liu, Weiping Liu, Jun Zhu, Ling Wang, Yuqin Song, Chen Zhang   +8 more
wiley   +1 more source

Phase II study of maintenance trifluridine/tipiracil (TAS-102) plus bevacizumab after induction chemotherapy in metastatic colorectal cancer. [PDF]

Oncologist
Ota K, Uemura M, Tanida T, Nakata K, Kudo T, Kagawa Y, Haraguchi N, Minami S, Matsuura Y, Ota H, Hiraki M, Yasui M, Takahashi H, Iwamoto K, Nishida N, Hata T, Nishizawa Y, Fukunaga M, Komori T, Takahashi Y, Tokuyama S, Tamagawa H, Naito A, Yoshihara T, Suzuki R, Sugimoto S, Miyake M, Takiguchi N, Tei M, Tamai K, Fukada A, Ogino T, Miyoshi N, Satoh T, Yamamoto H, Murata K, Doki Y, Eguchi H.   +37 more
europepmc   +1 more source