Results 161 to 170 of about 63,127 (238)

Early‐Onset Gastric Cancer as a High‐Risk Disease Entity in the United States: Clinicopathologic Features, Regional Variation, and Outcomes

Cancer Medicine, Volume 15, Issue 8, August 2026.
ABSTRACT Introduction Early‐onset gastric cancer (EOGC), defined as diagnosis before age 45, represents a distinct and increasingly recognized subset of gastric cancer. Emerging evidence suggests that clinical behavior, treatment patterns, and outcomes differ from average‐onset disease, yet these differences remain incompletely characterized.
Dani R. Castillo, Pranati Shah, Derek Tai, Mengni Guo, Max Hazeltine, Sofia Guzman, Daniel Park, Rifat Mannan, Yan Xing, Gagandeep Brar, Mustafa Raoof, Cathy Eng, Shengyang Wu   +12 more
wiley   +1 more source

A next-generation multimetal complex induces immunogenic cell death with distinct transcriptomic signatures.

Chem Commun (Camb)
Babu T, Levine MS, Zeng B, Sessler JL.
europepmc   +1 more source

Copy number alteration fingerprint predicts the clinical response of oxaliplatin-based chemotherapy in metastatic colorectal cancer. [PDF]

NPJ Precis Oncol
Weng J, Wang J, Tao Z, Wu T, Diao K, Wang J, Wang N, Ye Z, Zhang R, Shen J, Zhao X, Li X, Li X, Liu XS.   +13 more
europepmc   +1 more source

Comparison of Thrombocytopenia and Splenomegaly in Locally Advanced Rectal Cancer Patients Receiving Total Neoadjuvant Therapy With and Without Immunotherapy

Cancer Medicine, Volume 15, Issue 8, August 2026.
ABSTRACT Background Thrombocytopenia is a common toxicity of oxaliplatin‐based chemotherapy and may be linked to hepatic sinusoidal obstruction and splenic enlargement. In the TORCH trial, adding PD‐1 blockade to an oxaliplatin‐containing total neoadjuvant therapy (TNT) regimen improved tumor response in patients with locally advanced rectal cancer ...
Shuwen Li, Mingxu Yan, Qiong Ma, Yiqun Sun, Zhen Zhang, Lijun Shen, Juefeng Wan, Hui Zhang, Ruiyan Wu, Fan Xia, Yaqi Wang   +10 more
wiley   +1 more source

Megestrol acetate versus dexamethasone to prevent nausea and vomiting in patients with gastric or gastro-oesophageal junction cancer treated with oxaliplatin-based chemotherapy: study protocol of a multicentre, randomised, non-inferiority trial. [PDF]

BMJ Open
Luo H, Hu Q, Zeng L, Huang Q, Luo Y, Li T, Chen P, Yi C, Gou H.   +8 more
europepmc   +1 more source

Dietary Terpenoids in Advancing Biofilm‐Mediated Cancer Prevention: Antibiofilm Cascade, Molecular Crosstalk, and Nano‐Facilitated Functional Delivery

Cell Biochemistry and Function, Volume 44, Issue 8, August 2026.
ABSTRACT The role of microbes in cancer is gaining attention these days, especially in the context of tumor‐associated biofilms and dysbiotic microbiota. Biofilm‐producing microorganisms, such as Fusobacterium nucleatum and Helicobacter pylori, trigger oncogenic inflammation and immune evasion in tumor initiation and progression, and in the development
Saikat Mazumder, Aditi Dey, Debasmita Bhattacharya, Dibyajit Lahiri, Moupriya Nag, Sudhriti Maity, Navin Kumar, Soumya Pandit, Vaseem Raja, Shubham Sharma, Shashi Prakash Dwivedi, Mithul Rajeev, Juwita Ratna Dewi, Lola Sanayeva, Dilbar Azimova   +14 more
wiley   +1 more source

Proximity Labelling Reveals the Compartmental Proteome of Murine Sensory Neurons. [PDF]

Eur J Pain
Sondermann JR, Barry AM, Xian F, Haberl T, Gomez-Varela D, Benseler F, Schreiner D, Brose N, Lipstein N, Schmidt M.   +9 more
europepmc   +1 more source

Synchronous Tumor of Colorectal Adenocarcinoma and Epstein‐Barr Virus‐Positive Diffuse Large B‐Cell Lymphoma: A Case Report

Clinical Case Reports, Volume 14, Issue 8, August 2026.
ABSTRACT The third reported case of synchronous colorectal adenocarcinoma and EBV‐positive DLBCL in an 87‐year‐old patient confirms the rarity of this synchronous tumor. Despite segmental resection, the patient died from postoperative complications, highlighting the need for multidisciplinary research into pathogenesis and management.
Fen Liu, Linlin Fan, Hong Yu, Zhiyong Wei   +3 more
wiley   +1 more source

Raltitrexed in Hepatocellular Carcinoma: Mechanistic Rationale and Clinical Evidence from Arterial-Based Therapies. [PDF]

J Hepatocell Carcinoma
Jia X, Ding Y, Chen Y, Wang W.
europepmc   +1 more source