Results 161 to 170 of about 104,817 (211)

Navigating the Genetic Risk of Chemotherapy‐Induced Hearing Loss in the Stria Vascularis

Clinical Pharmacology &Therapeutics, Volume 119, Issue 4, Page 846-858, April 2026.
Cisplatin is a chemotherapy drug that causes permanent hearing loss by damaging a critical tissue lining the inner ear, called the stria vascularis (SV). Currently, the molecular mechanisms of SV damage are largely unknown and the incidence of ototoxicity in patients cannot be reliably predicted.
Tara Lazetic, Deanne Nixie R. Miao, Britt I. Drögemöller, Alain Dabdoub, Julia M. Abitbol   +4 more
wiley   +1 more source

NALIRIFOX versus liposomal irinotecan plus fluorouracil/leucovorin as the second-line chemotherapy in gemcitabine refractory pancreatic adenocarcinoma: a real-world study. [PDF]

Ther Adv Med Oncol
Wong WZ, Chiang NJ, Lee KC, Yu HY, Tsai CJ, Hsu SJ, Lee PC, Chen MH, Huang HC, Li CP, Luo JC, Lee FY.   +11 more
europepmc   +1 more source

Long‐term results of palliative placement of very low‐axial force self‐expandable metallic stents for malignant colorectal obstruction

DEN Open, Volume 6, Issue 1, April 2026.
Abstract Objectives Stent placement is a standard option for palliative decompression in patients with malignant colorectal obstruction. Long‐term stent placement is associated with perforation, migration, and stent occlusion. Perforation is associated with life expectancy.
Rika Kyo, Takashi Sasaki, Shuntaro Yoshida, Hiroyuki Isayama, Tomonori Yamada, Toshiyuki Enomoto, Yorinobu Sumida, Toshio Kuwai, Masafumi Tomita, Takeaki Matsuzawa, Rintaro Moroi, Toshiyasu Shiratori, Yoshihisa Saida   +12 more
wiley   +1 more source

Concomitant Use of DPP-4 Inhibitors May Prevent the Development of Oxaliplatin-Induced Peripheral Neuropathy: A Retrospective Cohort Study. [PDF]

Clin Transl Sci
Koura Y, Mine K, Fujita S, Kawashiri T, Mori Y, Ueda M, Kaneko R, Hirota T, Uchida M, Kobayashi D.   +9 more
europepmc   +1 more source

Endoscopic Complete Response to Zolbetuximab for Advanced Gastric Cancer With Claudin 18.2 Positive: A Case Report

DEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT Recently, zolbetuximab combined with chemotherapy has been approved as a first‐line treatment for advanced gastric cancer (GC). However, to date, no endoscopic images demonstrating endoscopic complete response (eCR) to zolbetuximab plus chemotherapy have been reported.
Akinori Sasaki, Tomohiro Yamaba, Ayu Tachibana, Rika Kimura, Gaku Uchiyama, Tsubasa Yoshioka, Risa Okamoto   +6 more
wiley   +1 more source

Maintaining oxaliplatin therapy after hypersensitivity reactions: real-world experience with a desensitisation protocol. [PDF]

Clin Exp Med
Christodoulis E, Vlachostergios PJ, Connell J, Williams J, Hasan J, Mansoor W, Mullamitha S, Hubner RA, Braun M, Saunders MP, Marti Marti F, Angelakas A, Waddell T, Alam N, Kamposioras K.   +14 more
europepmc   +1 more source

Distal Bile Duct Metastasis From Rectal Cancer: The Diagnostic Contribution of Intraductal Ultrasonography

DEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT A 49‐year‐old male developed liver dysfunction during chemotherapy for rectal cancer located in the rectosigmoid region. Although magnetic resonance cholangiopancreatography initially indicated sclerosing cholangitis, endoscopic retrograde cholangiopancreatography and intraductal ultrasonography revealed multiple non‐contiguous intraductal ...
Shinji Monoe, Ryo Nishio, Arihiro Nakano, Yu Yasue, Takahiro Yamashita, Hitoshi Iwata   +5 more
wiley   +1 more source

Possible preventive effect of surgical glove compression therapy on oxaliplatin-induced peripheral neuropathy: study protocol of a multicentre, phase II/III, randomised controlled trial-the Hiroshima Surgical Study Group of Clinical Oncology (HiSCO)-12 trial. [PDF]

BMJ Open
Shimomura M, Ishikawa S, Miguchi M, Shinozaki K, Ikeda S, Kobayashi H, Nakahara M, Sumitani D, Shimizu W, Kohyama M, Saito Y, Mukai S, Hirata Y, Kochi M, Shimizu Y, Takakura Y, Yoshimitsu M, Kodama S, Uegami S, Yano T, Okuda H, Ohdan H, Hiroshima Surgical study group of Clinical Oncology (HiSCO).   +22 more
europepmc   +1 more source

A Genome‐Wide Association Study of Colorectal Cancer Mortality Outcomes Among Individuals of African and Admixture Ancestry

Molecular Carcinogenesis, Volume 65, Issue 4, Page 422-433, April 2026.
ABSTRACT African Americans have the highest colorectal cancer (CRC) mortality rates in the United States. We performed the first genome‐wide association study (GWAS) of overall and CRC‐specific mortality among African Americans with incident CRC to identify genetic contributors to CRC outcomes.
Thomas Lawler, Jirong Long, Rene Welch, Irene Ong, Oluwatoyosi Ogunmuyiwa, Rida A. Khatri, Martha Shrubsole, Shaneda Warren Andersen   +7 more
wiley   +1 more source

Absolute Bioavailability of Oxaliplatin After Intraperitoneal Administration by Electrostatic Pressurized Intraperitoneal Aerosol Chemotherapy (ePIPAC): Systemic Pharmacokinetics of the CRC-PIPAC-II Trial. [PDF]

Ann Surg Oncol
van den Heuvel TBM, Rauwerdink P, Hulshof E, van de Vlasakker VCJ, Moes DJAR, Pluimakers G, Rovers KPB, Creemers GJ, Burger PJWA, Nienhuijs SW, Wiezer RJ, Lurvink RJ, Boerma D, De Hingh IHJT, Deenen MJ.   +14 more
europepmc   +1 more source