Results 141 to 150 of about 32,827 (233)

Advances in Gastric Cancer Research: Insights Into Carcinogenesis, the Tumor Microenvironment, Metastasis, and Factors Influencing Prognosis

Annals of Gastroenterological Surgery, Volume 10, Issue 4, Page 984-994, July 2026.
ABSTRACT Background The Department of Gastroenterological Surgery at Kumamoto University has maintained a commitment to integrating cutting‐edge clinical practice with fundamental research, particularly concerning malignant diseases of the digestive tract.
Hideo Baba, Takatsugu Ishimoto, Yoshifumi Baba, Hiromitsu Hayashi, Masaaki Iwatsuki   +4 more
wiley   +1 more source

Characterisation and modulation of drug resistance in lung cancer cell lines [PDF]

, 2010
Chemotherapy drug resistance is a major obstacle in the treatment of cancer. It can result from an increase in levels of cellular drug efflux pumps such as P-glycoprotein (P-gp).
Dunne, Gráinne
core  

Establishment of oxaliplatin-resistant gastric cancer organoids: importance of myoferlin in the acquisition of oxaliplatin resistance

Establishment of oxaliplatin-resistant gastric cancer organoids: importance of myoferlin in the acquisition of oxaliplatin resistance
内容の要約
openaire  

Cholesterol‐Lowering Treatment Blocks Epithelial‐Mesenchymal Transition (EMT) Associated Invasiveness and Drug Resistance in Breast and Colorectal Adenocarcinoma Models

Cancer Medicine, Volume 15, Issue 7, July 2026.
ABSTRACT Background Epithelial‐mesenchymal transition (EMT) is a cellular process involved in the invasion and metastasis of cancer cells. Deregulated cellular cholesterol is associated with treatment resistance and metastatic potential in cancer cells; however, the link between EMT and cholesterol is unclear.
Shanen Perumal, Naaziyah Abdulla, Ruth Aronson, Mandeep Kaur   +3 more
wiley   +1 more source

Pyruvate Kinase M2 Mediates Apigenin‐Induced Energy Crisis and Apoptosis in Colon Cancer Cells

Food Frontiers, Volume 7, Issue 4, July 2026.
Apigenin, a dietary flavonoid with low toxicity, induces profound bioenergetic collapse in colon cancer cells by downregulating PKM2. This metabolic crisis, characterized by suppressed glycolysis and mitochondrial dysfunction, ultimately triggers robust apoptosis.
Ke Zhang, Xingtao Zhou, Xujie Wang, Mingyong Xie   +3 more
wiley   +1 more source

Apple Pomace Pectin for Gastroprotective Nutraceutical Delivery: Structure–Function Relationships and Nano/Microencapsulation Strategies for Gastric Ulcer Management

Food Frontiers, Volume 7, Issue 4, July 2026.
Apple pomace pectin is explored as a sustainable and multifunctional biomaterial for gastric ulcer management. Its unique structural features confer mucoadhesive, anti‐inflammatory, antioxidant, and anti‐Helicobacter pylori activities while enabling nano/microencapsulation of therapeutic agents.
Akash Dhiman, Shefali Arora, Parteek Prasher, Sukanya Chhetri, Pankaj Bhandari, William N. Setzer, Javad Sharifi‐Rad   +6 more
wiley   +1 more source

Immune, molecular and genetic profiles of gastric signet ring cell carcinoma: Recent progress and future challenges

International Journal of Cancer, Volume 159, Issue 1, Page 11-29, 1 July 2026.
Abstract Gastric signet ring cell carcinoma (GSRCC) is a special type of gastric cancer common in young women. Diffuse gastric cancer (DGC) begins with intramucosal lesions comprising differentiated GSRCC cells. Genetically, GSRCC and DGC are clonally identical, with their morphology influenced by extracellular Wnt signaling.
Qian Wang, Shuai Zhou, Xiongchao Fang, Xianli He, Gang Wang, Nan Wang   +5 more
wiley   +1 more source

Bovine Milk–Derived Extracellular Vesicles as Emerging Drug Delivery Platforms: Current Advances, Applications and Challenges

Journal of Extracellular Biology, Volume 5, Issue 7, July 2026.
ABSTRACT Extracellular vesicles (EVs) are nanosized lipid bilayer particles naturally secreted by cells, mediating intercellular communication and transporting diverse bioactive molecules. Among alternative EV sources, bovine milk‐derived EVs (BMEVs) have emerged as promising platforms for drug delivery due to their accessibility, scalability ...
Martina Brattini, Michelle D'Urso, Sofia Mariotto, Elena Butturini   +3 more
wiley   +1 more source

RNA Modifications in Tumor Microenvironment: A New Dimension for Cancer Treatment

MedComm, Volume 7, Issue 7, July 2026.
Tumor initiation and progression depend on a supportive and highly heterogeneous tumor microenvironment (TME). RNA modifications regulate signaling pathways and cytokine networks that shape TME dynamics, facilitating interactions between cancer cells and noncancerous stromal cells, and ultimately promoting immune evasion and tumor progression ...
Qiwen Li, Yating Sun, Shuibin Lin, Quan Yuan   +3 more
wiley   +1 more source

Intratumoral Microbiota in Tumor: Current Understandings and Future Perspectives

MedComm, Volume 7, Issue 7, July 2026.
Intratumoral bacteria are emerging as active regulators of cancer evolution rather than bystanders. This review outlines how tumor‐resident microbes drive tumor initiation and growth by inducing genomic instability, epigenetic reprogramming, oncogenic signaling, and chronic inflammation, while promoting metastatic spread via invasion, angiogenesis ...
Jiawei Chen, Yupan Bai, Lu Shen, Jiacheng Ying, Jie Xu, Jiayin Tang, Yujie Bao   +6 more
wiley   +1 more source