Results 21 to 30 of about 11,863 (256)

Cyclization of Hydrazones of 2-Acetyl-1-naphthol and 1-Acetyl-2-naphthol with Triphosgene. Synthesis of Spiro Naphthoxazine Dimers

Molecules, 2009
Cyclization of hydrazones derived from 2-acetyl-1-naphthol and 1-acetyl-2-naphthol with triphosgene gave naphtho[1,2-e]-1,3-oxazines, naphtho[2,1-e]-1,3-oxazines or their spiro dimers depending on the molar ratio of triphosgene used for the cyclization.
Hamad Zaid Alkhathlan, Sara Abdullah Al-Mazroa, Ahmed Amine Mousa, Mohammed Ali Al-Saad, Abdullah Mohammed Al-Majid, Abdullah Saad Al-Bogami   +5 more
doaj   +1 more source

Amidoalkyl Naphthols as Important Bioactive Substances and Building Blocks: A Review on the Current Catalytic Mannich-Type Synthetic Approaches

Applied Sciences, 2023
Currently, 1-amidoalkyl-2-naphthol derivatives are of increasing interest due to their biological activities and further use in the preparation of other important bioactive molecules, such as aminoalkyl naphthols and oxazines.
Hristo Petkov, Svilen P. Simeonov
doaj   +1 more source

N-Substituted Pyrido-1,4-Oxazin-3-Ones Induce Apoptosis of Hepatocellular Carcinoma Cells by Targeting NF-κB Signaling Pathway

Frontiers in Pharmacology, 2018
Hepatocellular carcinoma (HCC) is a fatal disease and ranked fifth in cancer related mortality. Persistent activation of NF-κB is responsible for the oncogenesis, metastasis, tumor evasion, anti-apoptosis, angiogenesis and proliferation in HCC. Therefore,
Chakrabhavi Dhananjaya Mohan, Hanumantharayappa Bharathkumar, Dukanya, Shobith Rangappa, Muthu K. Shanmugam, Arunachalam Chinnathambi, Sulaiman Ali Alharbi, Tahani Awad Alahmadi, Atanu Bhattacharjee, Peter E. Lobie, Amudha Deivasigamani, Kam Man Hui, Gautam Sethi, Basappa, Basappa, Kanchugarakoppal S. Rangappa, Alan Prem Kumar, Alan Prem Kumar, Alan Prem Kumar, Alan Prem Kumar   +19 more
doaj   +1 more source

Evaluation of the Antioxidant Activity of Cis/Trans-N-Phenyl-1,4,4a,5,8,8a-Hexahydro-3,1-Benzoxazin-2-Imines

Antioxidants, 2019
The growing interest in the chemistry of unsaturated ring-fused 1,3-heterocycles, in this particular case 1,3-oxazines, arise in part from their versatile pharmacological applications.
Guadalupe Firpo, María L. Ramírez, Martín S. Faillace, Maria dos R. Mendes de Brito, Ana P. S. Correia Lima e Silva, Jessica Pereira Costa, Marcela C. Rodríguez, Gustavo A. Argüello, Zsolt Szakonyi, Ferenc Fülöp, Walter J. Peláez   +10 more
doaj   +1 more source

Synthesis and Conformational Analysis of Naphthoxazine-Fused Phenanthrene Derivatives

Molecules, 2020
The synthesis of new phenanthr[9,10-e][1,3]oxazines was achieved by the direct coupling of 9-phenanthrol with cyclic imines in the modified aza-Friedel–Crafts reaction followed by the ring closure of the resulting bifunctional aminophenanthrols with ...
Khadija Belasri, Leila Topal, Matthias Heydenreich, Andreas Koch, Erich Kleinpeter, Ferenc Fülöp, István Szatmári   +6 more
doaj   +1 more source

Antiproliferative Activity of (−)‐Isopulegol‐based 1,3‐Oxazine, 1,3‐Thiazine and 2,4‐Diaminopyrimidine Derivatives

ChemistryOpen, 2022
A series of novel heterocyclic structures, namely 1,3‐oxazines, 1,3‐thiazines and 2,4‐diaminopyrimidines, were designed and synthesised. The bioassay tests demonstrated that, among these analogues, 2,4‐diaminopyridine derivatives showed significant ...
Fatima Z. Bamou, Dr. Tam M. Le, Bizhar A. Tayeb, Seyyed A. S. Tahaei, Dr. Renáta Minorics, Prof. Dr. István Zupkó, Prof. Dr. Zsolt Szakonyi   +6 more
doaj   +1 more source

Clerodendrum colebrookianum extract mediated synthesis of AgNPs and its effective application as a sustainable catalyst for Oxazine transformation in neat condition and antibacterial activity.

Chemical Physics Impact, 2022
Silver nanoparticles (AgNPs) were synthesized through greener route using the Ethanol extract of Clerodendrum colebrookianum leaves. The synthesized AgNPs were characterized and confirmed through using various analytical studies like FT-IR, UV–vis, XRD ...
Putusenla Imchen, Betokali K Zhimomi, Toka Swu, Tovishe Phucho   +3 more
doaj   +1 more source

Easy Access to New Heterocyclic Systems:  1,4-Oxazine and Substituted 1,4-Oxazines [PDF]

The Journal of Organic Chemistry, 2007
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Elise, Claveau, Isabelle, Gillaizeau, Jérome, Blu, Amélie, Bruel, Gérard, Coudert   +4 more
openaire   +2 more sources

[3+3]-Annulation of Cyclic Nitronates with Vinyl Diazoacetates: Diastereoselective Synthesis of Partially Saturated [1,2]Oxazino[2,3-b][1,2]oxazines and Their Base-Promoted Ring Contraction to Pyrrolo[1,2-b][1,2]oxazine Derivatives

Molecules, 2023
A rhodium(II)-catalyzed reaction of cyclic nitronates (5,6-dihydro-4H-1,2-oxazine N-oxides) with vinyl diazoacetates proceeds as a [3+3]-annulation producing bicyclic unsaturated nitroso acetals (4a,5,6,7-tetrahydro-2H-[1,2]oxazino[2,3-b][1,2]oxazines ...
Yulia A. Antonova, Yulia V. Nelyubina, Sema L. Ioffe, Andrey A. Tabolin   +3 more
doaj   +1 more source

One-pot synthesis of naphtho[1,2-e][1,3]oxazines in the presence of FNAOSiPAMP*/CuII as an almond shell based nanocatalyst

Scientific Reports, 2022
In the present research work, a novel catalyst based on natural material, namely, Fe3O4@nano-almondshell@OSi(CH2)3/NHCH2pyridine/CuII abbreviated (FNAOSiPAMP/CuII) was designed and prepared.
Mina Keihanfar, Bi Bi Fatemeh Mirjalili
doaj   +1 more source