Polarity of liquid mixtures with components of limited miscibility [PDF]
, 1986 Binary mixtures of organic solvents with limited miscibility are investigated by a two parameter equation which reliably describes the polarity of mixtures as a function of their composition.
Dimroth +13 more
core +1 more source
Sorption of Sulfonamide Antibiotics in Peat Soils With Different Properties
Journal of Plant Nutrition and Soil Science, Volume 188, Issue 3, Page 482-494, June 2025.Sulfonamide antibiotics contaminate peat soils where they are sorbed to functional groups in a pH‐dependent manner that can be successfully described by QSAR. ABSTRACT Background Sulfonamide antibiotics have been discovered as emerging pharmaceutical pollutants worldwide and are only poorly removed in wastewater treatment.
Eric Mirenga, Sören Thiele‐Bruhn
wiley +1 more source
Recurrence of the oxazole motif in tubulin colchicine site inhibitors with anti-tumor activity
European Journal of Medicinal Chemistry Reports, 2021 Because of its wide spectrum of targets and biological activities, the oxazole ring is a valuable heterocyclic scaffold in the design of new therapeutic agents with anticancer, antiviral, antibacterial, anti-inflammatory, neuroprotective, antidiabetic ...
Marilia Barreca +7 more
doaj
N‐ to C‐Peptide Synthesis, Arguably the Future for Sustainable Production
Journal of Peptide Science, Volume 31, Issue 6, June 2025.The advent of epimerization‐free methods for coupling in N‐ to C‐direction synthesis offers improved atom economy for sustainable peptide synthesis. ABSTRACT A revolution in peptide production arrived from the innovation of carboxylate to amine C‐ to N‐direction solid‐phase synthesis.
Kinshuk Ghosh, William D. Lubell
wiley +1 more source
Repositioning Antitubercular 6-Nitro-2,3-dihydroimidazo[2,1-b][1,3]oxazoles for Neglected Tropical Diseases: Structure-Activity Studies on a Preclinical Candidate for Visceral Leishmaniasis. [PDF]
, 2016 6-Nitro-2,3-dihydroimidazo[2,1-b][1,3]oxazole derivatives were initially studied for tuberculosis within a backup program for the clinical trial agent pretomanid (PA-824).
Blaser, Adrian +12 more
core +3 more sources
Discovery and In Vitro Reconstitution of Closoxazole Biosynthesis from Pyxidicoccus fallax
ChemBioChem, Volume 26, Issue 10, May 27, 2025.The myxobacterium Pyxidicoccus fallax is found to be a producer of benzoxazole‐containing natural products named closoxazoles. In vitro studies with the biosynthetic enzymes reveal new insights into the reaction mechanism for closoxazole formation.
Lucia Lernoud +4 more
wiley +1 more source
Ueber Oxazole und Derivate [PDF]
Berichte der deutschen chemischen Gesellschaft, 1888 n ...
openaire +3 more sources
Photocarboxylation of Arylated 2H‐Azirines Exploiting Continuous Flow Technology
European Journal of Organic Chemistry, Volume 28, Issue 18, May 23, 2025.An efficient continuous process for the synthesis of trisubstituted oxazoles is reported which links the photochemical opening of azirines and the subsequent trapping of the azomethine ylides with CO2 gas. This highlights challenges and solutions when incorporating CO2 as a feedstock material for the photochemical synthesis of small heterocyclic ...
Arlene Bonner +2 more
wiley +1 more source
Frontiers in Chemistry, 2019 A palladium-catalyzed three-component reaction between 5-(2-chloroquinolin-3-yl) oxazoles, isocyanides, and water to yield 3-(oxazol-5-yl)quinoline-2-carboxamides is described.
Zahra Yasaei +4 more
semanticscholar +1 more source
Photoactivatable prodrugs of butyric acid based on new coumarin fused oxazole heterocycles [PDF]
, 2017 New coumarin fused oxazoles were investigated as photosensitive units for carboxylic acid groups using butyric acid as a model compound. 6-Oxo-6H-benzopyrano[6,7-d]oxazol-8-yl)methyl derivatives possessing various (hetero)aromatic substituents at ...
Ana M.S. Soares +36 more
core +1 more source