Results 21 to 30 of about 18,651 (251)

Benzobisoxazole cruciforms: a tunable, cross-conjugated platform for the generation of deep blue OLED materials [PDF]

, 2016
Four new cross-conjugated small molecules based on a central benzo[1,2-d:4,5-d′]bisoxazole moiety possessing semi-independently tunable HOMO and LUMO levels were synthesized and the properties of these materials were evaluated experimentally and ...
Cai, Min, Chavez, Ramiro, Jeffries-EL, Malika, Kaudal, Rajiv, Shinar, Joseph, Shinar, Ruth, Tlach, Brian, Tomlinson, Aimee L., Tsyrenova, Ayuna, Wheeler, David L.   +9 more
core   +1 more source

Ligand selectivity in stabilising tandem parallel folded G-quadruplex motifs in human telomeric DNA sequences [PDF]

, 2014
Biophysical studies of ligand interactions with three human telomeric repeat sequences (d(AGGG(TTAGGG)n, n = 3, 7 and 11)) show that an oxazole-based ‘click’ ligand, which induces parallel folded quadruplexes, preferentially stabilises longer telomeric ...
Alex R. O. Cousins, Balkwill, Bejugam, Biffi, Brooks, De Armond, De Cian, Dougal Ritson, Feng, Fernando, Fletcher, Garner, Grand, Haider, Huppert, John E. Moses, Kim, Kumari, Lingner, Lipps, Malcolm F. G. Stevens, Mark S. Searle, Mergny, Moorhouse, Moorhouse, Nakamura, Neidle, Pallavi Sharma, Petraccone, Petraccone, Randall, Renciuk, Ritson, Searle, Siddiqui-Jain, Todd, Vorlickova, Wang, Xu   +38 more
core   +1 more source

2,4,5-Tris(pyridin-4-yl)-4,5-dihydro-1,3-oxazole

Acta Crystallographica Section E, 2012
In the title compound, C18H14N4O, the molecules are disordered about a crystallographic twofold axis, leading to 50:50 disorder of the O- and N-atom sites within the oxazole ring. As a consequence, symmetry-related oxazole C—N and C—O
José J. Campos-Gaxiola, Herbert Höpfl, Gerardo Aguirre, Miguel Parra-Hake   +3 more
doaj   +1 more source

Design, Synthesis, In Vitro Biological Evaluation and In Silico Molecular Docking Study of Benzimidazole-Based Oxazole Analogues: A Promising Acetylcholinesterase and Butyrylcholinesterase Inhibitors

Molecules, 2023
Alzheimer’s disease (AD) is a degenerative neurological condition that severely affects the elderly and is clinically recognised by a decrease in cognition and memory.
Rafaqat Hussain, Fazal Rahim, Hayat Ullah, Shoaib Khan, Maliha Sarfraz, Rashid Iqbal, Faiza Suleman, Mohammad Khalid Al-Sadoon   +7 more
doaj   +1 more source

Naturally Occurring Oxazole-Containing Peptides [PDF]

Marine Drugs, 2020
Oxazole-containing peptides are mostly of marine origin and they form an intriguing family with a broad range of biological activities. Here we classify these peptides on the basis of their chemical structure and discuss a number of representatives of each class that reflect the extraordinary potential of this family as a source of new drugs.
Jessica T. Mhlongo, Edikarlos Brasil, Beatriz G. de la Torre, Fernando Albericio   +3 more
openaire   +3 more sources

2-(Naphthalen-1-yl)-4-(thiophen-2-ylmethylidene)-1,3-oxazol-5(4H)-one

Acta Crystallographica Section E, 2011
The asymmetric unit of the title compound, C18H11NO2S, contains two crystallographically independent molecules. In one molecule, the oxazole and thiophene rings are oriented at dihedral angles of 17.40 (9) and 18.18 (7)° with
Cevher Gündoğdu, Serap Alp, Yavuz Ergün, Barış Tercan, Tuncer Hökelek   +4 more
doaj   +1 more source

The nature of the silicaphilic fluorescence of PDMPO [PDF]

, 2015
PDMPO (2-(4-pyridyl)-5-((4-(2-dimethylaminoethylaminocarbamoyl)methoxy)phenyl)oxazole), has unique silica specific fluorescence and is used in biology to understand biosilicification.
Amat, Becke, Carole C. Perry, Charier, de Sousa Neto, DePedro, Dewar, Diwu, Diwu, Diwu, Durkin, Durkin, Elbergali, Faver, Francisco J. Martin-Martinez, Geerlings, Hammett, Hazelaar, Hilal, Hodson, Humphrey, Hurwitz, Ichinomiya, Ichinomiya, Kucki, Lakowicz, Law, Lee, Leffler, Li, Marini, Markus J. Buehler, Mataga, Mithun Parambath, Neese, Ogane, Ong, Perry, Plimpton, Quentin S. Hanley, Roach, Saxton, Scarminio, Shimizu, Tristan Giesa   +44 more
core   +1 more source

Isomerization of 5-(2H-Azirin-2-yl)oxazoles: An Atom-Economic Approach to 4H-Pyrrolo[2,3-d]oxazoles

Molecules, 2021
An atom economical method for the preparation of variously substituted 4H-pyrrolo[2,3-d]oxazoles was developed on the basis of thermal isomerization of 5-(2H-azirin-2-yl)oxazoles.
Timur O. Zanakhov, Ekaterina E. Galenko, Mariya A. Kryukova, Mikhail S. Novikov, Alexander A. Khlebnikov   +4 more
doaj   +1 more source

Total synthesis of the post-translationally modified polyazole peptide antibiotic goadsporin [PDF]

, 2017
The structurally unique polyazole antibiotic goadsporin contains six heteroaromatic oxazole and thiazole rings integrated into a linear array of amino acids that also contains two dehydroalanine residues.
Arnison, Bagley, Bredenkamp, Connell, Davies, Doyle, Doyle, El-Faham, Haginaka, Hughes, Igarashi, Kaul, Lin, Linder, Nicolaou, Onaka, Onaka, Onaka, Onaka, Ozaki, Platzer, Wada, Wipf   +22 more
core   +2 more sources

Evaluation of the Interaction between Long Telomeric DNA and Macrocyclic Hexaoxazole (6OTD) Dimer of a G-quadruplex Ligand

Molecules, 2013
Macrocyclic hexaoxazole dimer of L2H2-6OTD-dimer (3) was newly synthesized as a telomeric G-quadruplex (G4) ligand, and interaction with long telomeric DNAs telo48, 72, and 96 was evaluated by means of electrophoresis mobility shift assay, CD spectra ...
Kazuo Nagasawa, Hiroyuki Seimiya, Takahiro Nakamura, Satoki Majima, Keisuke Iida   +4 more
doaj   +1 more source