Results 51 to 60 of about 9,110 (223)
Thiazole and oxazole building blocks for combinatorial synthesis
, 1999 Three thiazole and oxazole containing amino acids were synthesized in good yields by condensation-cyclization. The active functional groups used, a C-terminal imino ester or a C-terminal aldehyde, reacted with both the amino groups and side chains of ...
Martin, Lenore M., Hu, Bi Huang
core +1 more source
Naturally Occurring Oxazole-Containing Peptides
, 2020 Oxazole-containing peptides are mostly of marine origin and they form an intriguing family with a broad range of biological activities. Here we classify these peptides on the basis of their chemical structure and discuss a number of representatives of ...
Edikarlos Brasil +3 more
core +1 more source
An Approach to the Bis-oxazole Macrocycle of Diazonamides
, 2016 A convergent approach to a macrocyclic compound embodying the complete “eastern” quadrant of diazonamides is described. The opening sequence in this work relies on an oxazole-forming reaction devised earlier in this group, while a late step involves a ...
Marco A. Ciufolini (117202) +1 more
core +1 more source
Studies towards the Synthesis of Phorbazoles A-D: Formulation of the Pyrrole Oxazole Skeleton
, 1999 Synthetic approaches towards the synthesis of the pyrrole oxazole skeleton of phorbazoles A-D are described. An efficient synthesis of the pyrrole oxazole skeleton (19) from pyrrole and 4- methoxyacetophenone was developed.
Volter, KE +4 more
core +1 more source
Rapid Access to Photoswitchable RNA Binders: Fluorination Enhances Protein Rescue by Exon Inclusion
Chemistry – A European Journal, EarlyView.An adaptable approach, many light‐switchable RNA binders. We report a versatile strategy for rapidly synthesizing photoswitchable RNA binders. The ligands can target SMN2 pre‐mRNA, restoring the levels of the corresponding protein by exon‐inclusion rescue.
Lei Zhang +10 more
wiley +1 more source
Crystals, 2011 The crystal and molecular structure of the title compound, viz., (2Z)-2-[3-(4-methoxybenzoyl)-4,4-dimethyl-1,2,-oxazolidin-2-ylidene]-1-(4-methoxyphenyl)ethanone (4), is reported.
Robert A. Gossage +4 more
doaj +1 more source
European Journal of Organic Chemistry, EarlyView.Diarylethene‐containing cyclic tubulysin analogues were designed, synthesized, and evaluated as light‐responsive cytotoxic agents. One analogue showed reversible photoswitching, photoregulated tubulin polymerization inhibition, and photoform‐dependent cytotoxicity.
Anna Iampolska +9 more
wiley +1 more source
Conformational Properties of Oxazole-Amino Acids: Effect of the Intramolecular N–H···N Hydrogen Bond
, 2016 Oxazole ring occurs in numerous natural peptides, but conformational properties of the amino acid residue containing the oxazole ring in place of the C-terminal amide bond are poorly recognized.
Małgorzata A. Broda (1838209) +4 more
core +1 more source
Synthesis of donor-acceptor benzobis(oxazole) small molecules [PDF]
, 2013 A variety of symmetric, π-conjugated organic chromophores were synthesized using trans-benzobis(oxazole) as an acceptor and the core of dye, changing the donating moieties in the 2- and 6-positions.
Klimavicz, James
core +1 more source
Solid Phase versus Solution Phase Synthesis of Heterocyclic Macrocycles
Molecules, 2013 Comparing a solution phase route to a solid phase route in the synthesis of the cytotoxic natural product urukthapelstatin A (Ustat A) confirmed that a solid phase method is superior.
Shelli R. McAlpine, Seong Jong Kim
doaj +1 more source