Results 51 to 60 of about 9,421 (215)

Herbicide Losses From Terraced Tile Inlet Technologies

Ecohydrology, Volume 19, Issue 7, November/December 2026.
ABSTRACT Terraced agricultural fields in the Midwestern United States commonly use surface inlets to mitigate ponding and enhance drainage; however, these structures can also facilitate herbicide transport to downstream waters. This study evaluated four terraced tile inlet technologies: Hickenbottom riser (HBR), water quality inlet (WQI), blind inlet ...
Charchit Bansal, Gurbir Singh, Kelly A. Nelson, Gurpreet Kaur   +3 more
wiley   +1 more source

Development and validation of the method of quantification of 5-[5-(trifluoromethyl)-1,2-oxazole-3-yl]-furan-2-sulfonamide and its metabolites in laboratory animal plasma

Разработка и регистрация лекарственных средств
Introduction. The study of the systemic exposure of a new original drug is an essential part of its preclinical study. 5-[5-(trifluoromethyl)-1,2-oxazole-3-yl]-furan-2-sulfonamide is a new selective carbonic anhydrase II inhibitor for the treatment of ...
I. I. Yaichkov, M. K. Korsakov, A. A. Shetnev, N. N. Volkhin, S. S. Petukhov   +4 more
doaj   +1 more source

Poly[3-methyl-1,3-oxazolidin-2-iminium[µ₃-cyanido-tri-µ₂-cyanido-κ⁹C:N-tricuprate(I)]]

Molbank, 2021
The unexpected formation of an oxazole ring has occurred during synthesis of a copper(I) cyanide network polymer as part of our ongoing studies of the structural chemistry of these networks. Crystals of the title compound were formed during the synthesis
Leena N. Rachid, Peter W. R. Corfield
doaj   +1 more source

Nucleophilic Aromatic Substitution in the Gas Phase

Journal of Physical Organic Chemistry, Volume 39, Issue 11, November 2026.
In this review, we highlight experimental studies of gas‐phase SNAr. Studying reactions in the gas phase provides invaluable information on intrinsic reactivity by eliminating the complications of solvent effects. Because SNAr is a fundamental reaction in chemical research and organic synthesis, understanding its underlying reactivity and mechanisms is
Daniel N. Hirsch, Damon J. Hinz, Jeehiun K. Lee   +2 more
wiley   +1 more source

The Diazo Route to Diazonamide A. Studies on the Indole Bis-oxazole Fragment

, 2016
Various approaches to the indole bis-oxazole fragment of the marine secondary metabolite diazonamide A are described, all of which feature dirhodium(II)-catalyzed reactions of diazocarbonyl compounds in key steps.
James R. Davies (2358214), Peter D. Kane (2672131), Christopher J. Moody (1304406)   +2 more
core   +1 more source

Density Functional Theory Applied to Excited State Intramolecular Proton Transfer in Imidazole-, Oxazole-, and Thiazole-Based Systems

Molecules, 2018
Excited state intramolecular proton transfer (ESIPT) is a photoinduced process strongly associated to hydrogen bonding within a molecular framework. In this manuscript, we computed potential energy data using Time Dependent Density Functional Theory ...
Fabricio de Carvalho, Maurício D. Coutinho Neto, Fernando H. Bartoloni, Paula Homem-de-Mello   +3 more
doaj   +1 more source

A KATing Edge Perspective on KAT6A Inhibitors as Anticancer Agents

ChemMedChem, Volume 21, Issue 20, 28 October 2026.
This perspective efficiently summarizes the development of lysine acetyltransferase (KAT) inhibitors as anticancer agents, and the most clinically advanced KAT6A inhibitor, prifetrastat, entered Phase III clinical trials in 2025. KAT6A structural biology and structure activity relationships for acylsulfonylhydrazides, [1,2,4]thiadiazines, and ...
Rochelle Woodland, Adi Suwandi, Awgichew Behaile Teklemariam, Nidhish Francis, Li Li, Kenneth A. Chinkwo, Jonathan B. Baell, David J. Leaver   +7 more
wiley   +1 more source

Oxazole Synthesis from Isocyanides

, 2012
International audienceA new synthetic path toward oxazoles starting from isocyanides is presented. This two-step oxazole preparation involves a bromination-cyclization followed by a Suzuki cross-coupling.
Patil, Pravin, Grimaud, Laurence, El Kaim, Laurent   +2 more
core   +1 more source

Cyclization of Activated Methylene Isocyanides with Methyl N(N),N′-Di(tri)substituted Carbamimidothioate: A Novel Entry for the Synthesis of N,1-Aryl-4-tosyl/ethoxycarbonyl-1H-imidazol-5-amines

SynOpen, 2019
Base-induced cyclization of active methylene isocyanides with carbamimidothioates for the synthesis of N,1-aryl-4-tosyl/ethylcarboxy-1H-imidazol-5-amines is reported.
Dukanya Dukanya, Toreshettahally R. Swaroop, Shobith Rangappa, Kanchugarakoppal S. Rangappa, Basappa Basappa   +4 more
doaj   +1 more source

Rapid Access to Photoswitchable RNA Binders: Fluorination Enhances Protein Rescue by Exon Inclusion

Chemistry – A European Journal, Volume 32, Issue 39, 22 October 2026.
An adaptable approach, many light‐switchable RNA binders. We report a versatile strategy for rapidly synthesizing photoswitchable RNA binders. The ligands can target SMN2 pre‐mRNA, restoring the levels of the corresponding protein by exon‐inclusion rescue.
Lei Zhang, Nemanja Djokovic, Alexander Herr, Anna Wacker, Emily Swanson Hay, Daniel Santana, Amanda E. Hargrove, Harald Schwalbe, Katarina Nikolic, Frank Abendroth, Olalla Vázquez   +10 more
wiley   +1 more source