Results 61 to 70 of about 5,801 (188)

Brain‐Wide Mapping and Synaptic Localization of C1QL3 Using a Novel Epitope‐Tagged Knock‐In Mouse

Journal of Comparative Neurology, Volume 534, Issue 8, August 2026.
C1QL3 is a secreted adhesion molecule that acts as a key regulator of synaptic structure and function. We generated and validated a novel epitope‐tagged knock‐in mouse line (C1ql32HA) in which two hemagglutinin (HA) epitopes were inserted near the N‐terminus of the endogenous C1QL3 protein.
William P. Armstrong IV, James M. Salvatore, Matthew J. Sticco, Keaven Caro, J. Wesley Maddox, Angie Huang, Brenna C. McAllister, Christopher B. O'Connell, Siu‐Pok Yee, Amy Lee, Susanne Ressl, David C. Martinelli, Alexander C. Jackson   +12 more
wiley   +1 more source

Synthesis of 6-Nitroderivatives of Oxazolo[3,2-a]-pyridines and Their Reactions with Nucleophiles

Molecules, 2003
5-Nitro-2-pyridone can be selectively N-phenacylated, and the resulting phenacylpyridones I undergo cyclization to 6-nitrooxazolo[3,2-a]pyridinium salts II.
Eugene V. Babaev, Alexander A. Bush
doaj   +1 more source

Azole‐Based Diarylbenzenes for Molecular Solar Thermal Energy Storage: A Computational Analysis

ChemistrySelect, Volume 11, Issue 29, 3 August 2026.
Diarylethenes containing aromatic π‐linkers have attracted research interest in recent years owing to their potential applications in molecular solar thermal (MOST) energy storage systems. In this work, we demonstrate that replacing the thienyl core of diarylbenzenes with an oxazole core and introducing lateral alkyl‐substituents on the oxazole core ...
Thillaiarasi Sukumar, M. V. R. Akshay Sampath, D. Bala Karuna Kumar, Bhagyashri Devaru Bhat, Mahesh Kumar Ravva, Baswanth Oruganti   +5 more
wiley   +1 more source

Deactivation Pathways in 2‐Ferrocenylmethyl‐5‐Aminoxazoles Synthesized via Ugi–Zhu Reaction: A Dewar–Chatt–Duncanson‐Type Interaction

ChemistrySelect, Volume 11, Issue 29, 3 August 2026.
The synthesis and full characterization are reported of 15 new ferrocenyl‐containing oxazoles via the Ugi–Zhu reaction, which is a special kind of MCR versatile to synthesize different types of heterocycles and polyheterocycles, and the DFT‐based study is performed using a high level of theory to rationalize the reactivity of synthesized compounds ...
Carlos E. Garduño‐Albino, Roberto E. Blanco‐Carapia, Ricardo Alfredo Luna‐Mora, Humberto Laguna‐Galindo, Eduardo González‐Zamora, Alejandro Islas‐Jácome   +5 more
wiley   +1 more source

Heterogeneous Organocatalytic Synthesis of Propargylic Esters Using a Polymer‐Supported N‐Heterocyclic Carbene

ChemSusChem, Volume 19, Issue 14, 29 July 2026.
A vinyl addition polynorbornene (VA‐PNB)‐supported N‐Heterocyclic carbene precatalyst is successfully used in the metal‐free coupling of terminal alkynes, carbon dioxide, and chlorides toward propargylic esters. The conversion of carbon dioxide into high‐value chemical scaffolds is a central challenge in modern green chemistry. In this study, we report
Dimitrios K. Giannopoulos, Entzy Kaplanai, Carlos Lendínez, Sozan N. Abdullah, Ana C. Albéniz, Georgios C. Vougioukalakis   +5 more
wiley   +1 more source

Identification and synthesis of metabolites of the new antiglaucoma drug

Research Results in Pharmacology
Introduction: The determination of biotransformation products is an essential part of the preclinical trial of original medicines. These studies have not been conducted before for the new drug 5-[5-(trifluoromethyl)-1,2-oxazole-3-yl]-furan-2-sulfonamide.
Alexander L. Khokhlov, Ilya I. Yaichkov, Anton А. Shetnev, Sergey A. Ivanovsky, Mikhail K. Korsakov, Mikhail A. Alexeev, Olga A. Gasilina, Nikita N. Volkhin, Sergey S. Petukhov   +8 more
doaj   +1 more source

Funktionalisierung von Peptiden auf der festen Phase im späten Synthesestadium

Angewandte Chemie, Volume 138, Issue 31, 27 July 2026.
Peptidmodifikationen sind für die Kontrolle der Eigenschaften von Peptidwirkstoffen von entscheidender Bedeutung. Daher sind Strategien, die einen effizienten und schnellen Einbau nicht‐kanonischer Modifikationen in Peptide in Parallelformaten ermöglichen, sehr gefragt.
Marius Werner, Truc Lam Pham, Franziska Thomas   +2 more
wiley   +1 more source

Total Synthesis of Bacterial 5-(3-Indolyl)oxazole Alkaloids: Pimprinols A–C

SynOpen, 2019
Pimprinols A, B, and C are bacterial 5-(3-indolyl)oxazole alkaloids that have been isolated from Streptomyces sp. Lv3–13. In this paper, we report a new synthesis of pimprinol A and the first total synthesis of pimprinol B and pimprinol C.
Tímea Szabó, Róbert Kormány, András Dancsó, Balázs Volk, Mátyás Milen   +4 more
doaj   +1 more source

Late‐Stage Functionalization of Peptides on the Solid Phase

Angewandte Chemie International Edition, Volume 65, Issue 31, 27 July 2026.
Peptide modifications are essential to control pharmacodynamic and pharmacokinetic properties of peptide drugs. Consequently, strategies that allow for efficient and rapid incorporation of non‐canonical modifications into peptides in parallel formats are highly sought after.
Marius Werner, Truc Lam Pham, Franziska Thomas   +2 more
wiley   +1 more source

Crystal structure and Hirshfeld surface analysis of 5-[(5-nitro-1H-indazol-1-yl)methyl]-3-phenyl-4,5-dihydroisoxazole

Acta Crystallographica Section E: Crystallographic Communications, 2019
In the title compound, C17H14N4O3, the indazole unit is planar to within 0.0171 (10) Å and makes dihedral angles of 6.50 (6) and 6.79 (4)°, respectively, with the nitro and pendant phenyl groups.
Mohammed Boulhaoua, Sevgi Kansiz, Mohamed El Hafi, Sanae Lahmidi, Necmi Dege, Mohammed Benchidmi, Joel T. Mague   +6 more
doaj   +1 more source