Results 81 to 90 of about 14,808 (226)

A pilot study of the novel J-PET plastic scintillator with 2-(4-styrylphenyl)benzoxazole as a wavelength shifter [PDF]

, 2015
For the first time a molecule of 2-(4-styrylphenyl)benzoxazole containing benzoxazole and stilbene groups is applied as a scintillator dopant acting as a wavelength shifter. In this article a light yield of the plastic scintillator, prepared from styrene
Bednarski, T., Białas, P., Czerwiński, E., Danel, A., Gajos, A., Gruntowski, A., Kamińska, D., Kapłon, Ł., Kochanowski, A., Korcyl, G., Kowal, J., Kowalski, P., Kozik, T., Krzemień, W., Kubicz, E., Molenda, M., Moskal, P., Niedźwiecki, Sz., Pałka, M., Raczyński, L., Rudy, Z., Rundel, O., Salabura, P., Sharma, N. G., Silarski, M., Smyrski, J., Strzelecki, A., Słomski, A., Uchacz, T., Wieczorek, A., Wiślicki, W., Zieliński, M., Zoń, N.   +32 more
core   +2 more sources

AlkaPlorer: A database‐driven explorer for natural alkaloids and derivatives

Journal of Integrative Plant Biology, Volume 68, Issue 5, Page 1384-1398, May 2026.
The alkaloid database AlkaPlorer integrates over 130,000 compounds across 12,250 species. By linking chemical structures with biological and evolutionary data, it reveals how these molecules evolve and function. This platform serves as a vital resource for AI‐driven discovery in plant metabolism and modern drug development. ABSTRACT Alkaloids, renowned
Jiahao Li, Tao Zeng, Hongquan Xu, Xu Kang, Minghui Liang, Ruibo Wu   +5 more
wiley   +1 more source

The McKenna reaction – avoiding side reactions in phosphonate deprotection

Beilstein Journal of Organic Chemistry, 2020
The McKenna reaction is a well-known and popular method for the efficient and mild synthesis of organophosphorus acids. Bromotrimethylsilane (BTMS) is the main reagent in this reaction, which transforms dialkyl phosphonate esters into bis(trimethylsilyl ...
Katarzyna Justyna, Joanna Małolepsza, Damian Kusy, Waldemar Maniukiewicz, Katarzyna M. Błażewska   +4 more
doaj   +1 more source

One-pot multi-reaction processes: synthesis of natural products and drug-like scaffolds [PDF]

, 2014
One-pot multi-reaction processes involving Overman rearrangements, metathesis cyclizations, and Diels–Alder reactions have been developed for the rapid and efficient synthesis of amino-substituted carbocyclic and heterocyclic compounds.
Calder, Ewen D.D., Grafton, Mark W., Sutherland, Andrew   +2 more
core   +1 more source

Total synthesis of the post-translationally modified polyazole peptide antibiotic goadsporin [PDF]

, 2017
The structurally unique polyazole antibiotic goadsporin contains six heteroaromatic oxazole and thiazole rings integrated into a linear array of amino acids that also contains two dehydroalanine residues.
Arnison, Bagley, Bredenkamp, Connell, Davies, Doyle, Doyle, El-Faham, Haginaka, Hughes, Igarashi, Kaul, Lin, Linder, Nicolaou, Onaka, Onaka, Onaka, Onaka, Ozaki, Platzer, Wada, Wipf   +22 more
core   +2 more sources

Synthesis of Highly Substituted Oxazoles through Iodine(III)-Mediated Reactions of Ketones with Nitriles

Molecules, 2012
In the presence of trifluoromethanesulfonic acid (TfOH) or bis(trifluoromethane-sulfonyl)imide (Tf2NH), iodosobenzene (PhI=O) efficiently promoted the reactions of dicarbonyl compounds as well as monocarbonyl compounds with nitriles to give 2,4 ...
Yuji Hanzawa, Akio Saito, Nao Hyodo
doaj   +1 more source

Cation-induced ring-opening and oxidation reaction of photoreluctant spirooxazine–quinolizinium conjugates

Beilstein Journal of Organic Chemistry, 2020
Two new spiroindolinonaphthoxazine derivatives with an electron-accepting styrylquinolizinium or styrylcoralyne unit, respectively, were synthesized, and the influence of such an arylvinyl substituent on the chemical and photochemical properties of the ...
Phil M. Pithan, Sören Steup, Heiko Ihmels   +2 more
doaj   +1 more source

Modulating IDO1 and TDO Inhibition Through Structural Modification of Diaryl Hydroxylamines

ChemMedChem, Volume 21, Issue 7, 14 April 2026.
Diaryl hydroxylamines have emerged as promising scaffolds for targeting the tryptophan‐catabolizing enzymes indoleamine 2,3‐dioxygenase 1 (IDO1) and tryptophan 2,3‐dioxygenase (TDO), key drivers of tumor immune escape. Building on the reported dual IDO1/TDO inhibitory activity of O‐((3,5‐difluorophenyl)(phenyl)methyl)hydroxylamine, a series of diaryl ...
Angeliki S. Foscolos, Alexandros Pappas, Christos N. Petroulias, Anna Kapella, Georgia M. Prifti, Grigoris Zoidis, Minas Papadopoulos, Anastasia Mpakali, Aristeidis Chiotellis   +8 more
wiley   +1 more source

Молекулярний докінг похідних 1,3-оксазолу в активному центрі тубуліну [PDF]

, 2017
Досліджено in silico вплив похідних 1,3-оксазолу на колхіцинзв'язуючий сайт (КЗС) β-тубуліну, проведено молекулярний докінг похідних 1,3-оксазолу в КЗС β-тубуліну та наведено результати аналізу ліганд-рецепторних комплексів.
Лобко, Є.О., Метелиця, Л.О., Семенюта, І.В., Танчук, В.Ю.   +3 more
core   +1 more source

Copper‐ and Silver‐Catalyzed Reactions of Active Methylene Isocyanides: Facile Access to Highly Substituted Five‐ and Six‐Membered Heterocycles

Chemistry – A European Journal, Volume 32, Issue 13, 1 April 2026.
This review summarizes recent advances in copper‐ and silver‐catalyzed reactions of active methylene isocyanides for the synthesis of highly substituted five‐ and six‐membered heterocycles. Emphasis is placed on [3+n] cycloadditions, annulations, and asymmetric strategies, highlighting current limitations and future opportunities in heterocycle ...
Jimil George, Kyungsoo Oh
wiley   +1 more source