Results 101 to 106 of about 2,355 (106)
Decarboxylative Isomerization of N-Acyl-2-oxazolidinones to 2-Oxazolines
, 2016 N-Acyl-2-oxazolidinones are ring-opened by lithium iodide and decarboxylated in the presence of a mild proton source. Further reaction with an amine base provides 2-oxazolines.
Aaron E. May (2031505) +2 more
core +1 more source
Iodine‐Triggered Cyclization of Epoxy Carbamates: A Practical Route to Oxazolidinones
Oxazolidinones are important heterocycles widely found in pharmaceuticals and biologically active molecules. Herein, we report an iodine‐mediated cyclization of epoxy benzyl carbamates that provides an efficient route to C5‐hydroxymethyl‐substituted ...
Cheng‐Kun Lin +3 more
core +1 more source
Multigram-Scale Preparation of Sugar-Based Spiro-Oxazolidinones
Oxazolidinones and their derivatives have attracted attention in various areas of drug development for antibacterial activity, herbicides, pesticides, and many other ...
Lugiņina, Jevgeņija +4 more
core
Oxazolidinones represent a new class of antituberculosis drugs that exert their function by inhibiting protein synthesis. Here, we compared the activities of three oxazolidinones, linezolid, PNU-100480, and AZD5847, against latent tuberculosis using a ...
Vocat, Anthony +8 more
core +1 more source