Results 101 to 110 of about 17,792 (252)
Enzymatic C(sp3)-H Amination: P450-Catalyzed Conversion of Carbonazidates into Oxazolidinones
ACS Catalysis, 2015 Cytochrome P450 enzymes can effectively promote the activation and cyclization of carbonazidate substrates to yield oxazolidinones via an intramolecular nitrene C–H insertion reaction.
Ritesh Singh +3 more
semanticscholar +1 more source
Brazilian Journal of Infectious DiseasesLinezolid was the first clinically applied member of the new antimicrobial class called the "oxazolidinones". These agents have a powerful spectrum of activity focussed against Gram-positive organisms including strains with documented resistances to ...
Charles H. Ballow +3 more
doaj +1 more source
Cost-effectiveness of different MRSA screening methods.
, 2002 We describe a model to examine the cost-effectiveness of various laboratory-screening approaches to detect methicillin-resistant Staphylococcus aureus (MRSA).
Cookson, B +4 more
core +1 more source
Remodelling of the natural product fumagillol employing a reaction discovery approach [PDF]
, 2011 In the search for new biologically active molecules, diversity-oriented synthetic strategies break through the limitation of traditional library synthesis by sampling new chemical space. Many natural products can be regarded as intriguing starting points
Balthaser, Bradley R. +4 more
core +1 more source
Antimicrobial activity of linezolid against Gram-positive cocci isolated in Brazil
Brazilian Journal of Infectious Diseases, 2001 The new oxazolidinone linezolid and other antimicrobial agents used to treat Gram-positive infections were tested against 1,585 Gram-positive cocci; 1,260 staphylococci and enterococci isolates from patients hospitalized in Brazilian hospitals, and 325 S.
Sader Helio S. +2 more
doaj
New and old oxazolidinones: tedizolid vs. linezolid [PDF]
Клиническая микробиология и антимикробная химиотерапия, 2017 Tedizolid is a novel oxazolidinone that has been recently approved for the treatment of acute bacterial skin and skin structure infections (ABSSSIs) caused by Gram-positive pathogens, including MRSA.
Dekhnich A.V., Hachatryan N.N.
doaj
The fecal resistome of dairy cattle is associated with diet during nursing. [PDF]
, 2019 Antimicrobial resistance is a global public health concern, and livestock play a significant role in selecting for resistance and maintaining such reservoirs.
DePeters, Edward J +7 more
core +1 more source
Linezolid: The First Oxazolidinone Antimicrobial
Annals of Internal Medicine, 2003 Linezolid is the first of a new class of antimicrobial agents, the oxazolidinones, to be approved for clinical use in the United States and elsewhere. The drug is a totally synthetic compound, which lessens the likelihood of naturally occurring resistance mechanisms.
openaire +2 more sources
, 2005 Es fa un breu repàs a un seguit d'antimicrobians, analitzant els seus mecanismes d'acció i els principals mecanismes de resistència.A brief report of action mechanisms in a series of antimicrobial agents is performed, taking resistance mechanisms into ...
Santos, Carmen +2 more
core