Results 91 to 100 of about 2,355 (106)
, 2018 Correction to “Design, Synthesis, and Antibacterial Evaluation of Oxazolidinones with Fused Heterocyclic C‑Ring ...
Nidhi Jain (1507936) +1 more
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Antimicrobial activity of linezolid against Gram-positive cocci isolated in Brazil
Brazilian Journal of Infectious Diseases, 2001 The new oxazolidinone linezolid and other antimicrobial agents used to treat Gram-positive infections were tested against 1,585 Gram-positive cocci; 1,260 staphylococci and enterococci isolates from patients hospitalized in Brazilian hospitals, and 325 S.
Sader Helio S. +2 more
doaj
Searching for Ideal Oxazolidinone for Treatment of Tuberculosis
Туберкулез и болезни лёгкихOxazolidinones represent a promising class of drugs for treatment of multidrug-resistant tuberculosis (MDR-TB). Linezolid, the first representative of this class, is highly effective; however, its use is limited due to its toxicity (myelosuppression ...
A. I. Gayda +5 more
doaj +1 more source
, 2016 A role of achiral oxazolidinones to enhance the enantioselectivity in reactions of N-cinnamoyloxazolidinones with alkyl radicals promoted by a chiral Lewis acid is described.
Hideyuki Tsutsui (2370460) +2 more
core +1 more source
New and old oxazolidinones: tedizolid vs. linezolid [PDF]
Клиническая микробиология и антимикробная химиотерапия, 2017 Tedizolid is a novel oxazolidinone that has been recently approved for the treatment of acute bacterial skin and skin structure infections (ABSSSIs) caused by Gram-positive pathogens, including MRSA.
Dekhnich A.V., Hachatryan N.N.
doaj
Antimycobacterial Activities of Novel 5-(1H-1,2,3-Triazolyl)Methyl Oxazolidinones
, 2020 The antibacterial activities of a series of triazolyl oxazolidinones against Mycobacterium tuberculosis strain in vitro and in vivo in a mice model are presented.
Edet Ekpenyong Udo +2 more
core
Brazilian Journal of Infectious Diseases, 2002 Linezolid was the first clinically applied member of the new antimicrobial class called the "oxazolidinones". These agents have a powerful spectrum of activity focussed against Gram-positive organisms including strains with documented resistances to ...
Ballow Charles H. +3 more
doaj
Palladium-Catalyzed Formation of Oxazolidinones from Biscarbamates: A Mechanistic Study
, 2020 Oxazolidinones can be synthesized starting from cyclic biscarbamates via a palladium-catalyzed reaction. To test the proposed mechanism of this reaction, first, bicyclonorcarene endoperoxides derived from cyano and carbomethoxy cycloheptatrienes were ...
Benan Kilbas, Metin Balci
core
, 2016 The synthetic correlation between two different antibiotic frameworks, the β-lactams and 2-oxazolidinones, is described for the first time. In this approach, 2-oxazolidinones are prepared in stereomerically pure form from 3-hydroxy β-lactams by a ring ...
Cristina M. Coates (2318938) +3 more
core +1 more source
An efficient chiral resolution of racemic baclofen using 2-oxazolidinones as chiral auxiliaries
Results in ChemistryAn efficient large-scale preparation of enantiomerically pure (R)- and (S)-baclofen hydrochloride is described. The principal feature of this approach is the practical resolution of N-Boc-protected baclofen using 2-oxazolidinones as chiral auxiliaries ...
Lili Yang +8 more
doaj +1 more source