Results 91 to 100 of about 6,381 (215)

Ribosomal RNA is the target for oxazolidinones, a novel class of translational inhibitors. [PDF]

, 1999
Oxazolidinones are antibacterial agents that act primarily against gram-positive bacteria by inhibiting protein synthesis. The binding of oxazolidinones to 70S ribosomes from Escherichia coli was studied by both UV-induced cross-linking using an azido ...
Matassova, N., Wildhagen, Henning, Matassova, N. B., Rodnina, Marina, Matassova, Natalia B., Wintermeyer, Wolfgang, Endermann, R., Kroll, H. P., Rodnina, M., Pleiss, U., Wild, H., Rodnina, M. V., Wintermeyer, W., Kroll, H., Kroll, HP   +14 more
core   +1 more source

Enantioenriched Oxazolidinones as Synthesis Scaffolds and Efforts towards the Total Synthesis of Marineosin A [PDF]

, 2018
Enantioenriched Oxazolidinones as Synthesis Scaffolds and Efforts towards the Total Synthesis of Marineosin Feng Lang, PhD University of Pittsburgh, 2018 The utility of enantioenriched oxazolidinones in the preparation of small chiral building ...
Lang, Feng
core  

3,5-Disubstituted Oxazolidinones as Ligands to Bind to the T-Box Riboswitch

, 2023
The synthesis of novel 3,5-Disubstituted oxazolidinones will be done to test for RNA binding ...
Williams, Kurtis
core  

Poster Sessions

HemaSphere, Volume 10, Issue S1, June 2026.
wiley   +1 more source

Antimicrobial activity of linezolid against Gram-positive cocci isolated in Brazil

Brazilian Journal of Infectious Diseases, 2001
The new oxazolidinone linezolid and other antimicrobial agents used to treat Gram-positive infections were tested against 1,585 Gram-positive cocci; 1,260 staphylococci and enterococci isolates from patients hospitalized in Brazilian hospitals, and 325 S.
Sader Helio S., Gales Ana C., Jones Ronald N.   +2 more
doaj  

New and old oxazolidinones: tedizolid vs. linezolid [PDF]

Клиническая микробиология и антимикробная химиотерапия, 2017
Tedizolid is a novel oxazolidinone that has been recently approved for the treatment of acute bacterial skin and skin structure infections (ABSSSIs) caused by Gram-positive pathogens, including MRSA.
Dekhnich A.V., Hachatryan N.N.
doaj  

Unprecedented Effects of Achiral Oxazolidinones on Enantioselective Radical-Mediated Conjugate Additions Using a Chiral Zinc Triflate

, 2016
A role of achiral oxazolidinones to enhance the enantioselectivity in reactions of N-cinnamoyloxazolidinones with alkyl radicals promoted by a chiral Lewis acid is described.
Hideyuki Tsutsui (2370460), Masatoshi Murakata (1973812), Osamu Hoshino (3002043)   +2 more
core   +1 more source

Synthesis of Oxazolidinones from Epoxides and Isocyanates Catalysed by Aluminium Heteroscorpionate Complexes

, 2016
The combination of an aluminium(heteroscorpionate) complex and tetrabutylammonium bromide acts as a highly efficient catalyst system for the synthesis of oxazolidinones from epoxides and isocyanates.
North, Michael, Michael North, José A. Castro‐Osma, Otero, Antonio, Lara-Sánchez, Agustín, Castro-Osma, José A., Amy Earlam, Agustín Lara‐Sánchez, Antonio Otero, Earlam, Amy   +9 more
core   +1 more source

An efficient chiral resolution of racemic baclofen using 2-oxazolidinones as chiral auxiliaries

Results in Chemistry
An efficient large-scale preparation of enantiomerically pure (R)- and (S)-baclofen hydrochloride is described. The principal feature of this approach is the practical resolution of N-Boc-protected baclofen using 2-oxazolidinones as chiral auxiliaries ...
Lili Yang, Pingping Sun, Mengxin Zhang, Qian Ren, Junjie Zhu, Katsuhisa Horimoto, Feng Zhang, Lilin Wang, Dongyin Chen   +8 more
doaj   +1 more source

Decarboxylative Isomerization of N-Acyl-2-oxazolidinones to 2-Oxazolines

, 2016
N-Acyl-2-oxazolidinones are ring-opened by lithium iodide and decarboxylated in the presence of a mild proton source. Further reaction with an amine base provides 2-oxazolines.
Aaron E. May (2031505), Patrick H. Willoughby (2442745), Thomas R. Hoye (1313214)   +2 more
core   +1 more source