Results 71 to 80 of about 6,381 (215)

Applications of oxazolidinones as chiral auxiliaries in the asymmetric alkylation reaction applied to total synthesis

, 2022
Various chiral oxazolidinones (Evans’ oxazolidinones) have been employed as effective chiral auxiliaries in the asymmetric alkylation of different enolates.
Vahideh Zadsirjan (6272597), Behnaz Farajpour (9673459), Majid Mommahed Heravi (9225485)   +2 more
core   +1 more source

Linezolid: The First Oxazolidinone Antimicrobial

Annals of Internal Medicine, 2003
Linezolid is the first of a new class of antimicrobial agents, the oxazolidinones, to be approved for clinical use in the United States and elsewhere. The drug is a totally synthetic compound, which lessens the likelihood of naturally occurring resistance mechanisms.
Paterson, David L., Pasculle, A. William, McCurry, Kenneth   +2 more
openaire   +6 more sources

Push–Pull Ynamines and Push–Pull Ynamides: Synthesis, Structure, Reactivity, and Application

European Journal of Organic Chemistry, Volume 29, Issue 19, 22 May 2026.
Push–pull ynamines and push–pull ynamides, which carry an EWG and an amino or amido group as EDG, are highly interesting classes of EDG‐EWG alkynes that have been intensively studied due to their exceptional reactivity. In this review, the synthesis, structure, reactivity, and application of push–pull ynamines, push–pull ynecarbamates, push–pull ...
Hans‐Joachim Gais
wiley   +1 more source

A Multicomponent Route to Functionalized Amides and Oxazolidinones [PDF]

Organic Letters, 2017
An organobase-mediated multicomponent reaction of unactivated esters, epoxides, and amines is reported, furnishing functionalized amide derivatives. A wide range of substrates are tolerated under the reaction conditions, including chiral epoxides, which react with no erosion of enantiopurity.
McPherson, Christopher G., Cooper, Alasdair K., Bubliauskas, Andrius, Mulrainey, Paul, Jamieson, Craig, Watson, Allan J. B.   +5 more
openaire   +4 more sources

Asymmetric Transformations of α,β‐Unsaturated Oxazolidinones Catalyzed by C2‐Symmetric Chiral Iron Triad Complexes

Advanced Synthesis &Catalysis, Volume 368, Issue 9, 5 May 2026.
This review highlights the evolution of highly enantioselective oxazolidinone transformations enabled by C2‐symmetric ligands, with emphasis on chiral iron triad complexes as cost‐effective, environmentally benign alternatives to late‐transition‐metal catalysts.
Arthur David, Thierry Ollevier
wiley   +1 more source

A Genomic Catalog of Migratory Microbiomes from Wild Birds across China's Habitats

Advanced Science, Volume 13, Issue 26, 8 May 2026.
ABSTRACT Migratory birds play an important role in the spread of antimicrobial resistance (AMR); however, gaps in surveillance data from vital regions along migratory flyways across China limit the detection of emergent threats. Here, we assembled 340 metagenomes from 52 bird species covering 11 provincial administrative districts in China, presenting ...
Yanan Wang, Heqi Wu, Mengqi Qu, Chunge Zhang, Ziqian Xu, Yuhang Pei, Chaochao Zhao, Jiangtao Wang, Sufang Ma, Na Lyu, Xuebin Xu, Yuhai Bi, Baoli Zhu, George F. Gao   +13 more
wiley   +1 more source

Rapid Synthesis of Triazole Oxazolidinone Hybrid Molecules via Click Chemistry

Asian Journal of Organic Chemistry, Volume 15, Issue 5, May 2026.
A modular click strategy rapidly converts epoxy amines into ethynylated oxazolidinone cores, which are then diversified by CuAAC with azides to deliver triazole–oxazolidinone hybrid libraries in generally moderate‐to‐excellent yields. ABSTRACT We report a concise, modular strategy for the rapid synthesis of triazole–oxazolidinone hybrid molecules by ...
Xsingyi Lee, Nian‐Xuan Lin, Meng‐Hsia Tsai, Hui‐Yin Hsu, Cheng‐Kun Lin   +4 more
wiley   +1 more source

Reduction‐Controlled Tunable Synthesis of Covellite (CuS) Nanoparticles from Water‐Soluble Single‐Source Precursors

Small, Volume 22, Issue 27, 14 May 2026.
Amino acid‐derived Cu(II)‐dithiocarbamates were synthesized as water‐soluble single‐source precursors for low‐temperature hydrothermal decomposition toward covellite (CuS) nanoparticles. Their decomposition followed a reduction‐mediated pathway via Cu(I)‐dithiocarbamate intermediates, with the reduction step being rate‐limiting and readily tunable ...
Xiang Xu, Siqiao Huang, Desmond A. Koomson, Tannith‐Jade Cole, Yuanyang Xie, Jagodish C. Sarker, David Pugh, Cécile A. Dreiss, Graeme Hogarth   +8 more
wiley   +1 more source

Copper-catalyzed domino cyclization of propargylic alcohol with tosyl isocyanate to oxazolidinones

, 2016
A copper-catalyzed domino cyclization of propargylic alcohols with tosyl isocyanate for the synthesis of oxazolidinones has been developed. Various propargylic alcohols with an aryl or alkyl substituents worked smoothly to afford the corresponding ...
Xiu-Shuai Chen (3341609), Yan-Jun Liu (197444), Rui-Feng Yang (568223), Hu, Xiang-Ping, Liu, Yan-Jun, Hou, Chuan-Jin, Xiang-Ping Hu (1537561), Chen, Xiu-Shuai, Yang, Rui-Feng, Chuan-Jin Hou (2067520)   +9 more
core   +1 more source

Studies of 2-Oxazolidinones. III. Kinetics of the Pyrolytic Decarboxylation of 2-Oxazolidinones [PDF]

Bulletin of the Chemical Society of Japan, 1962
Abstract The kinetics of the pyrolytic decarboxylation of 3-substituted 2-oxazolidinones have been studied and the following results obtained. (1) This decomposition is an autocatalytic reaction, in which the amine formed acts as a catalyst.
Ryohei Oda, Masahiko Miyanoki, Masaya Okano   +2 more
openaire   +1 more source