Results 81 to 90 of about 17,792 (252)
A protocol for amide bond formation with electron deficient amines and sterically hindered substrates [PDF]
, 2016 A protocol for amide coupling by in situ formation of acyl fluorides and reaction with amines at elevated temperature has been developed and found to be efficient for coupling of sterically hindered substrates and electron deficient amines where standard
Andersen, Rikke +5 more
core +1 more source
MicrobiologyOpen, Volume 15, Issue 2, April 2026.This study shows a strong correlation between the β‐lactam susceptibility profile of a clinical isolate of Nocardia cyriacigeorgica and the activity of its β‐lactamase, NCY‐1. Inhibitors of NCY‐1 reduce the minimum inhibitory concentration of amoxicillin.
Julie Couston +8 more
wiley +1 more source
11CO2 Fixation: A Renaissance in PET Radiochemistry [PDF]
, 2013 Carbon-11 labelled carbon dioxide is the cyclotron-generated feedstock reagent for most positron emission tomography (PET) tracers using this radionuclide.
Collier, Thomas L +6 more
core +1 more source
MicrobiologyOpen, Volume 15, Issue 2, April 2026.Our results show that the COVID‐19 pandemic has a significant impact on the detection of pathogens and drug resistance in pleural effusion in Shandong Province. ABSTRACT To analyze the composition and drug resistance changes of pleural effusion in Shandong region from 2017 to 2024, and to provide a basis for clinical empirical treatment and future ...
Wenwen Yu +60 more
wiley +1 more source
Antibiotic resistance evolved via inactivation of a ribosomal RNA methylating enzyme. [PDF]
, 2016 Modifications of the bacterial ribosome regulate the function of the ribosome and modulate its susceptibility to antibiotics. By modifying a highly conserved adenosine A2503 in 23S rRNA, methylating enzyme Cfr confers resistance to a range of ribosome ...
Fujimori, Danica Galonić +3 more
core
Strengthening the Combination between Enzymes and Metals in Aqueous Medium: Concurrent Ruthenium-Catalyzed Nitrile Hydration - Asymmetric Ketone Bioreduction [PDF]
, 2018 We are indebted to the MINECO of Spain (CTQ2013-40591-P and CTQ2016-75986-P) and the Gobierno del Principado de Asturias(Project GRUPIN14-006) for financial support. E.
Cadierno Menéndez, Victorio +8 more
core +2 more sources
MedComm, Volume 7, Issue 4, April 2026.This graphical abstract shows the antibacterial potential of phytochemicals from 15 spices, showcasing key compounds, their extraction methods, and mechanisms of action. It highlights membrane disruption, ROS generation, enzyme inhibition, and biofilm prevention as core antibacterial pathways.
Hettiyahandi Binodh De Silva +3 more
wiley +1 more source
Identification of Natural Isonitriles Through Ligation to an Azomethine Imine Probe
Chemistry – A European Journal, Volume 32, Issue 11, 16 March 2026.The azomethine imine (AMI)–isonitrile (NC) ligation allowed for the chemoselective detection of natural isonitriles in bacteria and fungi. The reactivity‐based screening establishes a new stereogenic center, thereby allowing for facile distinction between chiral and achiral isonitriles. The work also unraveled a unique reactivity of isonitriles bearing
Maurice P. Biedermann +6 more
wiley +1 more source
The Use of Oxazolidinone Products in the Treatment of Urinary Infections
Počki, 2015 The clinical efficacy of oxazolidinones with a focus on linezolid application in urinary infections is presented. High activity of the drug in methicillin-resistant Staphylococcus aureus, Enterococcus faecium and Enterococcus faecalis resistant to ...
D.D. Ivanov, Ya.O. Dombrovskyi
doaj +1 more source
Asymmetric 1,3-dipolar cycloadditions of acrylamides [PDF]
, 2009 This critical review, which is relevant to researchers in synthetic organic chemistry, focuses on asymmetric 1,3-dipolar cycloadditions with acrylamides.
Kissane, Marie, Maguire, Anita R.
core +1 more source