Results 71 to 80 of about 5,630 (210)

The Extract of D. dasycarpus Ameliorates Oxazolone-Induced Skin Damage in Mice by Anti-Inflammatory and Antioxidant Mechanisms

open access: yesAntioxidants, 2018
Dictamni dasycarpus is a type of Chinese medicine made from the root bark of D. dasycarpus. It has been reported to show a wide spectrum of biological and pharmacological effects, for example, it has been used widely for the treatment of rheumatism ...
Tsong-Min Chang   +3 more
doaj   +1 more source

Ultra‐Fast and Reversible [2 + 2] Photocycloaddition Enabling Green Light‐Mediated Switching of Polymer Materials

open access: yesSmartMat, Volume 7, Issue 3, June 2026.
This research introduces an ortho‐palladated oxazolone moiety that can undergo rapid and reversible photocycloaddition by low‐intensity green light irradiation. Integration of such a photoresponsive function into crosslinked polymer structures enables rapid photo‐ and thermo‐switching of polymer properties, presenting a unique light‐directed covalent ...
Wai Lean Koay   +7 more
wiley   +1 more source

Intestinally-restricted Janus Kinase inhibition: a potential approach to maximize the therapeutic index in inflammatory bowel disease therapy

open access: yesJournal of Inflammation, 2017
Background An unmet need remains for safe and effective treatments to induce and maintain remission in inflammatory bowel disease (IBD) patients. The Janus kinase (JAK) inhibitor, tofacitinib, has demonstrated robust efficacy in ulcerative colitis ...
David T. Beattie   +8 more
doaj   +1 more source

The Inflammatory Response in the Murine Ovalbumin‐Induced Skin Inflammation Model Is Robust Despite Major Gut Microbiota Differences

open access: yesClinical and Translational Science, Volume 19, Issue 6, June 2026.
ABSTRACT Valid pre‐clinical animal models are essential for effective drug development in inflammatory skin diseases like atopic dermatitis. Most murine models exhibit low‐to‐moderate inflammatory responses with significant variability, undermining their validity and contributing to high drug attrition rates.
Ida Wang Henriksen   +5 more
wiley   +1 more source

Push–Pull Ynamines and Push–Pull Ynamides: Synthesis, Structure, Reactivity, and Application

open access: yesEuropean Journal of Organic Chemistry, Volume 29, Issue 19, 22 May 2026.
Push–pull ynamines and push–pull ynamides, which carry an EWG and an amino or amido group as EDG, are highly interesting classes of EDG‐EWG alkynes that have been intensively studied due to their exceptional reactivity. In this review, the synthesis, structure, reactivity, and application of push–pull ynamines, push–pull ynecarbamates, push–pull ...
Hans‐Joachim Gais
wiley   +1 more source

One-Pot Friedel−Crafts/Robinson−Gabriel Synthesis of Oxazoles Using Oxazolone Templates

open access: yes, 2016
We report herein a one-pot synthesis of 2,4,5-trisubstituted oxazoles via a Friedel−Crafts/Robinson−Gabriel synthesis using a general oxazolone template.
Jetze J. Tepe (1676119)   +1 more
core   +1 more source

IRMPD Spectroscopy Shows That AGG Forms an Oxazolone b2+ Ion

open access: yes, 2016
IRMPD Spectroscopy Shows That AGG Forms an Oxazolone b2 ...
Sung Hwan Yoon (2056969)   +5 more
core   +1 more source

Metal Complexes Containing Homoleptic Diorganoselenium(II) Ligands: Synthesis, Characterization and Investigation of Optical Properties

open access: yesMolecules
[(Z)-2′-{2-C6H5-(4H)-oxazol-5-one}CHC6H4]2Se (5, L1) and [(Z)-4′-{2-C6H5-(4H)-oxazol-5-one}CHC6H4]2Se (6, L2) were prepared, structurally characterized and used as ligands to obtain new metal complexes of types [MX(Ln)] [L1: M = Ag, X = OTf (7); M = Au ...
Darius Dumitraș   +3 more
doaj   +1 more source

Electrical monitoring of photoisomerization of block copolymers intercalated into graphene sheets

open access: yesNature Communications, 2020
Block copolymers are electrically insulating and therefore characterization with electrical or electrochemical methods is not possible. Here, the authors demonstrate electrical monitoring of the photoisomerization transition in a benzylidene oxazolone ...
Semin Kim   +9 more
doaj   +1 more source

Repeated hapten exposure induces persistent tactile sensitivity in mice modeling localized provoked vulvodynia.

open access: yesPLoS ONE, 2017
BackgroundVulvodynia is a remarkably prevalent chronic pain condition of unknown etiology. Epidemiologic studies associate the risk of vulvodynia with a history of atopic disease.
Jasmine Landry   +11 more
doaj   +1 more source

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