Results 61 to 70 of about 5,630 (210)

Initial OX40–OX40L Signaling Promotes a Skin‐Resident Memory T‐Cell Reservoir in Atopic Dermatitis

Allergy, EarlyView.
Takayoshi Komatsu‐Fujii, Ryota Asahina, Tatsuya Hasegawa, Satoshi Nakamizo, Saeko Nakajima, Toshiaki Kogame, Kenji Kabashima   +6 more
wiley   +1 more source

1,1‐Disubstituted Vinylbromides: Versatile Building Blocks for the Synthesis of Nitrogen‐Containing Heterocycles

European Journal of Organic Chemistry, Volume 29, Issue 23, 16 June 2026.
1,1‐Disubstituted vinylbromides are key intermediates for constructing nitrogen‐containing heterocycles. This review provides an overview of the synthetic applications of 1,1‐disubstituted vinylbromides and summarizes recent developments in reaction methodologies, mechanistic insights, and the structural diversity of N‐heterocyclic compounds accessible
Anne Westermeyer, Jun Fang, Chonghuo Liu, Guillaume Lefèvre, Gérard Guillamot, Phannarath Phansavath, Virginie Ratovelomanana‐Vidal   +6 more
wiley   +1 more source

Oxazolone exposure leads to early induction of systemic cytokines.

, 2018
(A-C) Bar graphs represent cytokines in serum and isolated splenocytes of oxazolone-treated mice in both early (6h) and late (24h) phases of the disease. Data are expressed as mean ± SEM as determined by the repeated-measures two-way ANOVA test.
Pedro J. Gomez-Pinilla (478993), Elisa Meroni (5264507), Guy E. Boeckxstaens (421150), Gert De Hertogh (256864), Simon Verheijden (5264513), Gianluca Matteoli (259596), Nathalie Stakenborg (508024), Gera Goverse (5264510)   +7 more
core   +1 more source

Induction of oxazolone-mediated features of atopic dermatitis in NOD-scid IL2Rγnull mice engrafted with human peripheral blood mononuclear cells

Disease Models & Mechanisms, 2013
SUMMARY Animal models mimicking human diseases have been used extensively to study the pathogenesis of autoimmune diseases and the efficacy of potential therapeutics.
Thomas Nolte, Maryam Zadeh-Khorasani, Orkhan Safarov, Franziska Rueff, Rita Varga, Nadja Herbach, Rüdiger Wanke, Andreas Wollenberg, Thomas Mueller, Roswitha Gropp, Eckhard Wolf, Matthias Siebeck   +11 more
doaj   +1 more source

Racemisation of Amino Acids: From Synthetic Challenge to Biological Significance

ChemBioChem, Volume 27, Issue 11, 15 June 2026.
Racemisation, once considered an undesirable synthetic side reaction, also occurs naturally in amino acids and influences biological processes. Evidence links stereochemical conversion to ageing, protein turnover, and cellular development. This review examines mechanisms, control strategies in synthesis, applications and implications in physiology ...
Othman Al Musaimi
wiley   +1 more source

New Methacrylic Oxazolone and Thiazolidinone Containing Polymers for Nonlinear OpticalApplications [PDF]

, 2008
Oxazalone and thiazolidinone derivatives were synthesized and their physicochemical properties are determined by absorption, HNMR spectroscopies. The third order nonlinear optical properties of oxazolone and thiazolidinone containing compounds were ...
Sahraoui, Bouchta, Smokal, Vitaliy, V. Smokal, B. Derkowska-Zielinska, Kolendo, Aleksey, Czaplicki, Robert, Krupka, Oksana, O. Krupka, R. Czaplicki, B. Sahraoui, A. Kolendo, Derkowska-Zielinska, Beata   +11 more
core   +1 more source

4-(2-Methoxybenzylidene)-2-phenyl-1,3-oxazol-5(4H)-one

Acta Crystallographica Section E, 2009
The title molecule, C17H13NO3, adopts a Z configuration about the central olefinic bond. The 2-phenyl ring is almost coplanar with the plane of the oxazolone ring system, making a dihedral angle of 2.03 (11)°.
Abdullah Mohamed Asiri, Mehmet Akkurt, Islam Ullah Khan, Muhammad N. Arshad   +3 more
doaj   +1 more source

A Short Synthesis of Cyclo(‐RGDfK) Using a Microflow Reactor

ChemistryEurope, Volume 4, Issue 6, June 2026.
An efficient synthesis of cyclo(‐RGDfK) was achieved by combining a one‐flow three‐component coupling (3CC) reaction via α‐amino acid N‐carboxy anhydrides with rapid macrolactamization using a microflow reactor. Precise control of the water content and base loading in the 3CC reaction enabled the gram‐scale synthesis of the desired tripeptides and ...
Naoto Yamasaki, Mina Kim, Kana Miyamoto, Yuma Otake, Kyohei Adachi, Daisuke Kubo, Shinichiro Fuse   +6 more
wiley   +1 more source

Intralesional Cytokines in Chronic Oxazolone-Induced Contact Sensitivity Suggest Roles for Tumor Necrosis Factor α and Interleukin-4 [PDF]

, 1998
An analysis was conducted of the cytokine profile and inflammatory response in oxazolone sensitized mouse skin. Following exposure to oxazolone, the intralesional production of inflammatory cytokines was demonstrable at the levels of both mRNA and ...
Newsholme, Stephen J., Webb, Edward F., Tzimas, Maritsa N., Griswold, Don E.   +3 more
core   +1 more source

Synthesis of New 4(3H)-Quinazolinone Derivatives Using 5(4H)-Oxazolones

Molecules, 2006
New derivatives of 5(4H)-quinazolinone containing 2-imidazolin-5-one rings have been prepared from 5(4H)-oxazolone derivatives.
Hojatollah Khabazzadeh, Ahmad Momeni Tikdari, Hooshang Hamidian   +2 more
doaj   +1 more source