Results 111 to 120 of about 12,078 (208)
The Journal of Clinical Pharmacology, Volume 66, Issue 10, October 2026.Abstract Topiramate (TPM) is used to treat seizures in adults and children ≥2 years. In children, TPM dosing is body weight based. It is unknown whether children with obesity may benefit from an alternative dosing strategy. We developed a novel physiologically based pharmacokinetic (PBPK) model for TPM that accounts for age‐ and obesity‐related changes
Patricia D. Maglalang +14 more
wiley +1 more source
The objective of this study was to assess the impact of acute and chronic treatment with oxcarbazepine on its anticonvulsant activity, neurological adverse effects, and protective index in mice.
Monika Banach, Kinga Borowicz-Reutt
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Contact Dermatitis, Volume 95, Issue 4, Page 349-357, October 2026.ABSTRACT Drug hypersensitivity reactions (DHRs) are common in children and are diagnostically challenging, with cutaneous manifestations being the most common presentation. Patch testing (PT) is a well‐established tool for investigating delayed T‐cell‐mediated reactions and is widely used in patients with contact dermatitis.
Gabriele Simonetti +7 more
wiley +1 more source
Oxcarbazepine in the treatment of childhood epilepsy
, 2003 In this study, oxcarbazepine was began as monotherapy to evaluate the efficacy and safety of the drug. Forty-two patients (19 females, 23 males) with partial or generalized epilepsy more than 4 years of age were included (mean age, 11.9 +/- 3.4 years ...
Sarioglu, B +4 more
core +1 more source
Internal Medicine Journal, Volume 56, Issue 10, Page 1765-1774, October 2026.Abstract Background Pharmacogenomic‐guided medication management optimises drug therapy to enhance patient outcomes. Despite clinical utility, implementation in Australia remains limited, partly due to the lack of clear and consistent guidance. Aim This study evaluated the presence and consistency of pharmacogenomic testing indication categories and ...
Ruby Soueid +4 more
wiley +1 more source
Oxcarbazepine-induced Stevens–Johnson syndrome: a pediatric case report
, 2017 Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis are two rare but life-threatening diseases characterized by detachment of epidermis, bullous skin lesions and mucous membrane erosions.
Can, Ceren +9 more
core +1 more source
Background: Carbamazepine and oxcarbazepine are commonly used antiseizure medications for pediatric focal epilepsy. Both drugs may alter serum sodium levels and cause adverse effects, but comparative pediatric data, particularly from South Asian settings,
Romana Akter Happy +4 more
core +1 more source
Effective Treatment of Paroxysmal Nonkinesigenic Dyskinesia With Oxcarbazepine
, 2016 Paroxysmal nonkinesigenic dyskinesia (PNKD) is a rare chronic disorder characterized by intermittent, non-movement-related involuntary movements. The response to currently available therapies is inconsistent and temporary. We describe here a patient with
Szekely, Anna +5 more
core +1 more source
A rare complication during oxcarbazepine use,complete atrioventricular block: Case report
, 2013 Oxcarbazepine, 10 keto analogue of carbamezepine, is an antiepileptic drug used pri manly for the treatment of focal and generalized tonic clonic seizures in adults and children.
DOĞAN, SAİT MESUT +2 more
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, 2015 Antonio Lopalco,1–3,* Hazem Ali,1,* Nunzio Denora,3 Erik Rytting1,4,5 1Department of Obstretrics and Gynecology, University of Texas Medical Branch, Galveston, TX, USA; 2Department of Pharmaceutical Chemistry, University of Kansas, Lawrence, KS ...
Ali H, Denora N, Lopalco A, Rytting E
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