Results 101 to 110 of about 12,078 (208)

Bridging computational and clinical strategies for presurgical identification of epileptogenic networks

Epilepsia Open, Volume 11, Issue 5, Page 1525-1540, October 2026.
Abstract Objective About one third of epilepsy patients are drug‐resistant. Resective epilepsy surgery remains a key treatment option but depends critically on accurate identification of the seizure onset zone (SOZ), which is still guided mainly by subjective visual inspection of electrophysiological signals.
Tena Dubcek, Debora Ledergerber, Kristina Koenig, Adham Elshahabi, Rafael Polania, Lukas Imbach   +5 more
wiley   +1 more source

The efficacy of ultrasound-guided pulsed radiofrequency in the treatment of primary glossopharyngeal neuralgia

Frontiers in Neurology
ObjectiveThis study evaluates the clinical efficacy and safety of ultrasound-guided long duration, high voltage pulse radiofrequency (PRF) in managing primary glossopharyngeal neuralgia (GPN).MethodsClinical data were retrospectively analyzed for 13 ...
Fubo Li, Hongcheng Lu, Gege Gong, Cehua Ou, Yue Zhang   +4 more
doaj   +1 more source

Possible Oxcarbazepine Inductive Effects on Aripiprazole Metabolism: A Case Report

, 2017
Oxcarbazepine is a cytochrome P450 (CYP) 3A4 inducer, which is structurally similar to carbamazepine. Although lacking Food and Drug Administration approval, oxcarbazepine is sometimes prescribed to treat aggressive behavior in youth with autism ...
Joshua G. Loveland, Jose de Leon, Ian R. McGrane   +2 more
core   +1 more source

Astrocyte subtype‐specific alterations in the dentate gyrus of individuals with mesial temporal lobe epilepsy

Epilepsia Open, Volume 11, Issue 5, Page 1651-1667, October 2026.
Abstract Objective Epilepsy affects approximately 50 million people worldwide and, although primarily attributed to neuronal dysfunction, increasing evidence highlights a critical role of glial cells, particularly astrocytes, in the pathophysiological mechanisms.
Chiara Lötzsch, Jakob Johann Schmidt, Daniel Delev, Roland Coras, Ingmar Blümcke, Ruth Beckervordersandforth   +5 more
wiley   +1 more source

Oxcarbazepine in Mood Disorders

, 2001
Patients with bipolar illness or schizoaffective disorder–manic type can present with a variety of symptoms and have mixed responses to treatment. This is especially true for patients who have rapid cycling or mixed bipolar illness.
John Norton
core   +1 more source

Salience network hub dysfunction is associated with cognitive impairment in self‐limited epilepsy with centrotemporal spikes: An OPM‐MEG study

Epilepsia Open, Volume 11, Issue 5, Page 1706-1717, October 2026.
Abstract Objective Self‐limited epilepsy with centrotemporal spikes (SeLECTS), although characterized by well‐controlled seizures, is frequently associated with persistent cognitive deficits in affected children. This study aimed to investigate whether hub dysfunction of the salience network (SN) is associated with cognitive impairment in SeLECTS ...
Chen Yang, Guangsheng Wu, Nan An, Tiejia Jiang, Yilong Wang, Wenbin Zhao, Wangyang Cao, Xiaofang Wang, Haiteng Jiang, Zhefeng Yuan   +9 more
wiley   +1 more source

Analysis of the antinociceptive interactions in two-drug combinations of gabapentin, oxcarbazepine and amitriptyline in streptozotocin-induced diabetic mice

, 2010
Antiepileptic and antidepressant drugs are the primary treatments for pain relief in diabetic neuropathy. Combination therapy is a valid approach in pain treatment, where a reduction of doses could reduce side effects and still achieve optimal analgesia.
Prostran, Milica, Vučković, Sonja M., Stepanović-Petrović, Radica, Ugrešić, Nenad, Micov, Ana, Tomić, Maja, Bošković, Bogdan, Radica M. Stepanović-Petrović, Bogdan Bošković, Maja A. Tomić, Milica Š. Prostran, Sonja M. Vučković, Nenad D. Ugrešić, Ana M. Micov   +13 more
core   +1 more source

Economic burden and cost determinants of epilepsy in Georgia: A longitudinal cost‐of‐illness study

Epilepsia Open, Volume 11, Issue 5, Page 1786-1800, October 2026.
Abstract Objective To assess the economic burden, cost components, and individual‐level determinants of outpatient epilepsy care in adults in Georgia. Methods This longitudinal study of epilepsy‐related costs in adults with active epilepsy attending a tertiary epilepsy centre in Tbilisi collected clinical and sociodemographic data over 6 months. Direct
Sofia Kasradze, Tamar Jishkariani, Eka Burkadze, Ketevan Mamasakhlisi, Marika Megrelishvili, Josemir W. Sander   +5 more
wiley   +1 more source

Efficacy and safety of levetiracetam vs. oxcarbazepine in the treatment of children with epilepsy: a systematic review and meta-analysis

Frontiers in Pediatrics
BackgroundLevetiracetam (LEV) and oxcarbazepine (OXC) are new antiseizure medications (ASMs). In recent years, OXC monotherapy is widely used in children with epilepsy; however, no consensus exists on applying LEV monotherapy among children with epilepsy.
Yuanyuan Liu, Yanxu Wang, Xingzhou Li, Xiaomin Wu   +3 more
doaj   +1 more source

DECREASE study: A European pool‐analysis of patients with significant reductions in concomitant antiseizure medications in cenobamate Early Access Programs

Epilepsia Open, Volume 11, Issue 5, Page 1812-1824, October 2026.
Abstract Objective To evaluate the effectiveness and tolerability of cenobamate in patients with a significant reduction in concomitant antiseizure medication (ASM) in European cenobamate Early Access Programs (EAPs). Method Anonymized patient data from real‐world studies/registries associated with European cenobamate EAPs were pooled.
Vicente Villanueva, Simona Lattanzi, Javier Peña‐Ceballos, Rhys H. Thomas, Juan Rodríguez‐Uranga, Zsófia Jordán, Bernhard J. Steinhoff, Randi von Wrede, Norman Delanty, Patrick B. Moloney, Roberta Roberti, Giovanni Boero, Laura Canafoglia, Nicola Specchio, Antonio Gambardella, Edoardo Ferlazzo, Francesca Felicia Operto, Elena Tartara, Hester Garratt, Dániel Fabó, Asier Gómez‐Ibáñez, Gustavo Torres‐Gaona, Yulia Novitskaya, Rainer Surges, Kevin Hampel, Andreas Schulze‐Bonhage   +25 more
wiley   +1 more source