Enantioselective HPLC-UV method for determination of eslicarbazepine acetate (BIA 2-093) and its metabolites in human plasma [PDF]
Eslicarbazepine acetate (BIA 2-093) is a novel central nervous system drug undergoing clinical phase III trials for epilepsy and phase II trials for bipolar disorder.
Alves, Gilberto +6 more
core
Did the French pregnancy pictogram change antiseizure medication use during pregnancy?
Abstract Objective The aim of this study was to assess the impact of introducing a pregnancy pictogram on medication packaging on the prescription and dispensation of antiseizure medications and on the maternal and neonatal outcomes for women exposed to these medications.
Mélanie Araujo +7 more
wiley +1 more source
Oxcarbazepine Adjunctive Therapy for Partial Seizures
The safety and efficacy of oxcarbazepine (OXC) as adjunctive therapy for refractory partial seizures were evaluated in 267 patients in a multicenter (47 centers in 8 countries; Argentina, Chile, Uruguay, Australia, New Zealand, Canada, Israel, and the ...
J Gordon Millichap
doaj +1 more source
Audit of use of stiripentol in adults with Dravet syndrome [PDF]
OBJECTIVES: There are very few data available in the literature on the use of stiripentol in adults with Dravet syndrome (DS). DS cases are increasingly recognized in adulthood, and more children with DS now survive to adulthood. The aim of the study was
Balestrini, S, Sisodiya, SM
core +1 more source
Abstract Objective Focal cortical dysplasia (FCD) causes drug‐resistant epilepsy requiring presurgical evaluation. Invasive electroencephalographic (EEG) studies demonstrate that sleep modulates epileptic activity, including interictal epileptiform discharges (IEDs), fast oscillations (FOs) in the beta (14–40 Hz) and gamma (40–80 Hz) frequency bands ...
Marcel Heers +13 more
wiley +1 more source
Evaluation of the Efficacy of Carbamazepine and Oxcarbazepine in Trigeminal Neuralgia
Introduction: Trigeminal neuralgia is characterized by the presence of sudden, intense and repetitive orofacial pain generated in one or more branches of the trigeminal nerve; carbamazepine and oxcarbazepine are the first-line drugs for its treatment ...
de la Cruz-Rodriguez, Ronald +4 more
doaj +1 more source
Perampanel Serum Concentrations in Adults With Epilepsy: Effect of Dose, Age, Sex, and Concomitant Anti-Epileptic Drugs [PDF]
BACKGROUND: Perampanel (PMP), a noncompetitive α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) glutamate receptor antagonist, is a novel anti-epileptic drug (AED) licensed for the adjunctive treatment of focal and generalized epilepsy.
Gougoulaki, M, Patsalos, PN, Sander, JW
core
Seizure outcome after switching antiepileptic drugs: A matched, prospective study. [PDF]
OBJECTIVE: Outcomes after changing antiepileptic drugs (AEDs) have largely been studied in single cohort series. We recently reported the first study to examine this question in a controlled manner.
Finamore, Jon Marc +5 more
core +2 more sources
Women with epilepsy: Evidence‐based counseling across the lifespan
Abstract Women with epilepsy (WWE) encounter distinct and evolving challenges across the lifespan that require clinical management extending beyond seizure control alone. Although awareness of sex‐specific aspects of epilepsy has increased, important gaps remain in their integration into routine care.
Barbara Tettenborn +7 more
wiley +1 more source
Cognitive Function During Oxcarbazepine Treatment for Partial Seizures
The effect of oxcarbazepine compared to standard antiepileptic drug therapy (carbamazepine and valproate) on cognitive function in 112 children and adolescents (ages 6 to 16 years) with newly diagnosed partial seizures was investigated in a multicenter ...
J Gordon Millichap
doaj +1 more source

