Results 21 to 30 of about 16,479 (221)
Evaluation of Antioxidant Effects of Antiepileptic Drugs in Adult Epileptic Patients: An Open Label, Non Randomised Interventional Study [PDF]
Journal of Clinical and Diagnostic Research, 2022 Introduction: Oxidative stress is one of the factors implicated in the pathogenesis of epilepsy. Various antiepileptic drugs can control seizures by several mechanisms that may involve reduction of oxidative stress.
B Swathi, D Aruna
doaj +1 more source
Efficacy and safety of eslicarbazepine acetate monotherapy in patients converting from carbamazepine. [PDF]
, 2018 OBJECTIVE: To evaluate the influence of prior use of carbamazepine (CBZ) and other antiepileptic drugs (AEDs) with a putatively similar mechanism of action (inhibition of voltage-gated sodium channels; VGSCs) on seizure outcomes and tolerability when ...
Abou-Khalil +11 more
core +2 more sources
Frontiers in Pharmacology, 2022 Aim: To provide a comparison of genotyping for HLA risk alleles versus patch testing to determine which of these two tests is a better diagnostic tool for cutaneous hypersensitivity reactions caused by anti-seizure medication.Methods: A literature study ...
Lisanne E. N. Manson +4 more
doaj +1 more source
HLA Risk Alleles in Aromatic Antiepileptic Drug-Induced Maculopapular Exanthema
Frontiers in Pharmacology, 2021 To characterize human leukocyte antigen (HLA) loci as risk factors in aromatic antiepileptic drug-induced maculopapular exanthema (AED-MPE). A case-control study was performed to investigate HLA loci involved in AED-MPE in a southern Han Chinese ...
Yi-Wu Shi +24 more
doaj +1 more source
Trigeminal neuralgia: new classification and diagnostic grading for practice and research [PDF]
, 2016 Trigeminal neuralgia (TN) is an exemplary condition of neuropathic facial pain. However, formally classifying TN as neuropathic pain based on the grading system of the International Association for the Study of Pain is complicated by the requirement of ...
CRUCCU, Giorgio +8 more
core +2 more sources
Newer drugs for focal epilepsy in adults [PDF]
, 2012 A 28 year old woman sees her general practitioner after experiencing what sounds like a convulsion without any apparent provoking factor. Over the past month she has also had “blank spells” during which her husband noticed her to be unresponsive.
Brodie, M., Kwan, P.
core +1 more source
Clinical considerations in transitioning patients with epilepsy from clonazepam to clobazam: a case series. [PDF]
, 2014 IntroductionIn treating refractory epilepsy, many clinicians are interested in methods used to transition patients receiving clonazepam to clobazam to maintain or increase seizure control, improve tolerability of patients' overall drug therapy regimens ...
Chung, Steve +4 more
core +1 more source
Therapeutic Drug Monitoring and Methods of Quantitation for Carbamazepine [PDF]
, 2017 Carbamazepine is an early anticonvulsant still used today in the treatment of several forms of epilepsy. An active metabolite in the human body contributes to its pharmacological effect.
Ana Vlasceanu +7 more
core +4 more sources
Bali Journal of Anesthesiology, 2023 Hyponatremia is the most common electrolyte abnormality encountered in neurosurgical practice. The pathophysiology for hyponatremia among neurosurgical patients is most commonly due to syndrome of inappropriate antidiuretic hormone secretion (SIADH ...
Swathi Mallikarjuna +3 more
doaj +1 more source
Frontiers in Neurology, 2022 ObjectiveThere is a lack of studies using the International League Against Epilepsy (ILAE) recommendation to define drug-resistant epilepsy (DRE).
Hire Hersi +3 more
doaj +1 more source