Results 41 to 50 of about 9,378 (173)

Pregabalin versus oxcarbazepine in painful diabetic neuropathy in elderly population: Efficacy and safety in terms of pain relief, cognitive function, and overall quality of life

Indian Journal of Pain, 2018
Background and Aims: The treatment of painful diabetic neuropathy (PDN) in elderly patients is challenging considering the adverse effects associated with long term use of drugs.
Syed H Amir, Farah Nasreen, Hammad Usmani, Sheelu S Siddiqi, Muazzam Hasan, Nazia Tauheed   +5 more
doaj   +1 more source

Epilepsy characteristics in patients with muscle‐eye‐brain disease: A systematic review of electroclinical features

Epileptic Disorders, EarlyView.
Abstract Background and Objectives Muscle‐Eye‐Brain disease (MEB) is a dystroglycanopathy that belongs to the congenital muscular dystrophies. Central nervous system manifestations include congenital brain abnormalities, neurodevelopmental delay, and epilepsy, making it a rare but important cause of developmental and epileptic encephalopathy.
Stefania Kalampokini, Evripidis Pityrigkas, Eleni Liouta, Georgia Pepe, Vasiliki Poulidou, Martha Spilioti, Vasilios K. Kimiskidis   +6 more
wiley   +1 more source

Preoperative limbic cortical thinning in mesial temporal lobe epilepsy surgical candidates is associated with pre‐existing and de novo postoperative depression

Epileptic Disorders, EarlyView.
Abstract Objective Depression is common in mesial temporal lobe epilepsy (mTLE), but its neuroanatomical basis—and overlap with major depressive disorder (MDD)—remains poorly defined. We investigated whether the cortical and subcortical alterations reported in MDD are also present in mTLE and leveraged the frequent occurrence of depression after ...
Philip Fink‐Jensen, Brice Ozenne, Ane Kloster, Bo Jespersen, Kirsten Vinter, Guido Rubboli, Martin Balslev Jørgensen, Sandor Beniczky, Melanie Ganz, Lars Hageman Pinborg   +9 more
wiley   +1 more source

Hemophagocytic lymphohistiocytosis associated with oxcarbazepine

The Turkish Journal of Pediatrics, 2019
Hemophagocytic lymphohistiocytosis (HLH) is a rare life-threatening multisystem disorder. Reports of the disorder as a side effect of drugs are extremely rare.
Serkan Kırık, Hatice Güneş, Sadık Yurttutan, Nafiz Sarışık, Can Acıpayam, Yasemin Kırık   +5 more
doaj   +1 more source

The Antiepileptic Drug Oxcarbazepine Inhibits the Growth of Patient-Derived Isocitrate Dehydrogenase Mutant Glioma Stem-like Cells

Cells, 2023
Patients diagnosed with isocitrate dehydrogenase mutant (IDHmut) gliomas suffer frequently from seizures. Although the clinical course is less aggressive than that of its IDH wildtype counterpart, recent discoveries have shown that epileptic activity can
Philip Dao Trong, Gerhard Jungwirth, Andreas Unterberg, Christel Herold-Mende, Rolf Warta   +4 more
doaj   +1 more source

Oxcarbazepine-induced Reversible Pancytopenia and Severe Hyponatremia in a Patient with Bipolar Affective Disorder: Two Case Reports

Journal of Clinical and Diagnostic Research
Oxcarbazepine is a widely used mood stabiliser in Bipolar Affective Disorder (BPAD) due to its favourable tolerability compared with carbamazepine. However, it is associated with serious adverse effects, including hyponatraemia and pancytopenia, which ...
Sowmya Peyouse, S Gopinath, Priya Shivashankar   +2 more
doaj   +1 more source

Corticocortical evoked potential amplitude is altered by cortical stimulation in epilepsy

Epilepsia, EarlyView.
Abstract Objective Neurostimulation is an established therapy for drug‐resistant epilepsy, but optimizing stimulation parameters remains a major challenge. Corticocortical evoked potential (CCEP) amplitude may serve as an immediate biomarker of neurostimulation effects, enabling rapid parameter optimization.
Bethany J. Stieve, Aaron F. Struck, Dillon Scott, Richard Chappell, Andrew T. Knox   +4 more
wiley   +1 more source

Long‐term prognosis of pharmacotherapy in newly diagnosed focal epilepsy patients and the predictive value of baseline seizure timing: A prospective cohort study

Epilepsia, EarlyView.
Abstract Objective Epilepsy is a highly heterogeneous neurological disorder with significant prognostic variability. Accurate long‐term outcome prediction remains a clinical challenge. We investigated pharmacotherapeutic prognosis and key predictors, particularly baseline seizure timing, to guide individualized treatment.
Lei Sun, Shouye Sun, Xinyue Zhang, Weihong Lin   +3 more
wiley   +1 more source

Gamma suppression correlates with thalamic stimulation therapeutic response in intractable epilepsy

Epilepsia, EarlyView.
Abstract Objective In patients with drug‐resistant epilepsy who undergo anterior nucleus of the thalamus (ANT) deep brain stimulation (DBS), efficacy is assessed months after therapy initiation and clinicians have no guidance when choosing stimulation parameters due to the lack of real‐time biomarkers.
Zachary T. Sanger, Xinbing Zhang, Thomas Lisko, Hafsa Farooqi, Steffen Ventz, Sandipan Pati, Thomas R. Henry, David P. Darrow, Michael C. Park, Theoden I. Netoff, Robert A. McGovern   +10 more
wiley   +1 more source

Vitamin D status among children and adolescents on anticonvulsant drugs in Southern Switzerland

Swiss Medical Weekly, 2014
INTRODUCTION: It is recognised that vitamin D status is often inadequate (
Vera Ramelli, Gian Paolo Ramelli, Sebastiano A. G. Lava, Giordano M. Siegenthaler, Marco Cantù, Mario G. Bianchetti, Alessandro Ceschi   +6 more
doaj   +1 more source