Results 51 to 60 of about 16,479 (221)

Oxcarbazepine for refractory epilepsy: systematic review of the literature

São Paulo Medical Journal
CONTEXT AND OBJECTIVE: It has been estimated that 50 million people worldwide suffer from epilepsy and around 30% will not achieve adequate control over the disease.
Humberto Saconato, Gilmar Fernandes do Prado, Maria Eduarda dos Santos Puga, Álvaro Nagib Atallah   +3 more
doaj   +1 more source

Pregabalin versus oxcarbazepine in painful diabetic neuropathy in elderly population: Efficacy and safety in terms of pain relief, cognitive function, and overall quality of life

Indian Journal of Pain, 2018
Background and Aims: The treatment of painful diabetic neuropathy (PDN) in elderly patients is challenging considering the adverse effects associated with long term use of drugs.
Syed H Amir, Farah Nasreen, Hammad Usmani, Sheelu S Siddiqi, Muazzam Hasan, Nazia Tauheed   +5 more
doaj   +1 more source

Comparison of tolerability and adverse symptoms in oxcarbazepine and carbamazepine in the treatment of trigeminal neuralgia and neuralgiform headaches using the Liverpool Adverse Events Profile (AEP) [PDF]

, 2015
Background Adverse effects of drugs are poorly reported in the literature . The aim of this study was to examine the frequency of the adverse events of antiepileptic drugs (AEDs), in particular carbamazepine (CBZ) and oxcarbazepine (OXC) in patients ...
A Beydoun, A Pereira, AA Al-Musaed, AP Aldenkamp, D Marazziti, D. R. Boniface, E. Besi, FG Gilliam, G Cruccu, G Stefano Di, GA Baker, GA Baker, GA Baker, GD Anderson, HJ Heller, J Brooks, J. M. Zakrzewska, JD Greenspan, JM Zakrzewska, JM Zakrzewska, JM Zakrzewska, JW Song, K Tan, KJ Meador, L Zorzela, M Salinsky, MA Miller, ML Berger, NI Landro, P Perucca, P Saini, PB Ferrell Jr, PR Culmer, R. Cregg, S Nadkarni, SM Smith, TJ Nicolson   +36 more
core   +1 more source

Phenotype Expansion of Malan Syndrome: New Cases and a Review of the Literature

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Malan syndrome is an ultra‐rare overgrowth syndrome caused by pathogenic variants or deletions in nuclear factor one X (NFIX) located at 19p13.2. Here, we report a comprehensive literature review and phenotyping of known patients with Malan syndrome and present a novel cohort of eight patients.
Alex F. Nisbet, Sylvie A. Adams, Zoe S. Katz, Christal G. Delagrammatikas, Kosuke Izumi, Winifred Sigal, Kim Ventarola, Elaine H. Zackai, Julia E. Reid, Grant T. Liu, Jennifer M. Kalish   +10 more
wiley   +1 more source

Hemophagocytic lymphohistiocytosis associated with oxcarbazepine

The Turkish Journal of Pediatrics, 2019
Hemophagocytic lymphohistiocytosis (HLH) is a rare life-threatening multisystem disorder. Reports of the disorder as a side effect of drugs are extremely rare.
Serkan Kırık, Hatice Güneş, Sadık Yurttutan, Nafiz Sarışık, Can Acıpayam, Yasemin Kırık   +5 more
doaj   +1 more source

The Antiepileptic Drug Oxcarbazepine Inhibits the Growth of Patient-Derived Isocitrate Dehydrogenase Mutant Glioma Stem-like Cells

Cells, 2023
Patients diagnosed with isocitrate dehydrogenase mutant (IDHmut) gliomas suffer frequently from seizures. Although the clinical course is less aggressive than that of its IDH wildtype counterpart, recent discoveries have shown that epileptic activity can
Philip Dao Trong, Gerhard Jungwirth, Andreas Unterberg, Christel Herold-Mende, Rolf Warta   +4 more
doaj   +1 more source

Clinical and neurophysiological changes in patients with pineal region expansions [Kliničke i neurofiziološke značajke u bolesnika s ekspanzivnim tvorbama pinealne regije] [PDF]

, 2013
In the last 20 years neurological and neurosurgical follow up of our patients with pineal region expansions (118 patients) pointed to certain clinical and neurophysiological regularities.
Hajnšek, Sanja, Lupret, Velimir, Mrak, Goran, Nanković, Sibila, Paladino, Josip, Petelin Gadže, Željka   +5 more
core  

Consistency and clarity of pharmacogenomic guidance in UK medicine patient information leaflets: A cross‐sectional analysis

British Journal of Clinical Pharmacology, EarlyView.
Pharmacogenomic (PGx) information has the potential to support the safe and effective use of medicines, yet there is uncertainty about how this information can be best communicated to patients. Summaries of product characteristics (SmPCs) and patient information leaflets (PILs) for all UK‐approved medicines with strong evidence supporting a PGx ...
Parth Narlawar, Chloe Ratcliffe, Videha Sharma, William G. Newman, Munir Pirmohamed, John McDermott   +5 more
wiley   +1 more source

Genetic and Immune Predictors for Hypersensitivity Syndrome to Antiepileptic Drugs [PDF]

, 2011
Hypersensitivity syndrome reactions (HSR) to antiepileptic drugs (AED) are associated with severe clinical cutaneous adverse reactions (SCAR).Our aims are: to assess HSRs to AEDs using the in vitro lymphocyte toxicity assay (LTA) in patients who ...
Lawrence Cohen, Manuela G. Neuman, Paul A. Hwang, Radu M. Nanau   +3 more
core   +1 more source

Pharmacokinetic-pharmacodynamic influence of N-palmitoylethanolamine, arachidonyl-2′-chloroethylamide and WIN 55,212-2 on the anticonvulsant activity of antiepileptic drugs against audiogenic seizures in DBA/2 mice [PDF]

, 2016
We evaluated the effects of ACEA (selective cannabinoid (CB)1 receptor agonist), WIN 55,212-2 mesylate (WIN; non-selective CB1 and CB2 receptor agonist) and N-palmitoylethanolamine (PEA; an endogenous fatty acid of ethanolamide) in DBA/2 mice, a genetic ...
AVAGLIANO, CARMEN, CALIGNANO, ANTONIO, Citraro, Rita, De Sarro, Giovambattista, Leo, Antonio, Navarra, Michele, Russo, Emilio, RUSSO, ROBERTO   +7 more
core   +1 more source