Results 51 to 60 of about 12,078 (208)

Pregabalin versus oxcarbazepine in painful diabetic neuropathy in elderly population: Efficacy and safety in terms of pain relief, cognitive function, and overall quality of life

Indian Journal of Pain, 2018
Background and Aims: The treatment of painful diabetic neuropathy (PDN) in elderly patients is challenging considering the adverse effects associated with long term use of drugs.
Syed H Amir, Farah Nasreen, Hammad Usmani, Sheelu S Siddiqi, Muazzam Hasan, Nazia Tauheed   +5 more
doaj   +1 more source

The Antiepileptic Drug Oxcarbazepine Inhibits the Growth of Patient-Derived Isocitrate Dehydrogenase Mutant Glioma Stem-like Cells

Cells, 2023
Patients diagnosed with isocitrate dehydrogenase mutant (IDHmut) gliomas suffer frequently from seizures. Although the clinical course is less aggressive than that of its IDH wildtype counterpart, recent discoveries have shown that epileptic activity can
Philip Dao Trong, Gerhard Jungwirth, Andreas Unterberg, Christel Herold-Mende, Rolf Warta   +4 more
doaj   +1 more source

The effect of anti‐seizure medications on exposure to statins: A systematic review and meta‐analysis

Epileptic Disorders, EarlyView.
Abstract Objectives Antiseizure medications (ASMs) can reduce the efficacy of statin treatment, partly due to reduction in statin concentrations. In this systematic review and network meta‐analysis (NMA), we compared the effects of ASMs and the prototypical enzyme inducer rifampin on statin exposure.
Sharon Valiyev Huino, Hagar Cohen, Bruria Hirsh Raccah, Tomer Ben‐Shushan, Ilan Matok, Sara Eyal   +5 more
wiley   +1 more source

Carbamazepine, oxcarbazepine, and eslicarbazepine

, 2018
Carbamazepine is a first-generation antiepileptic drug characterized by a good range of antiepileptic indications, with acceptable risk of interactions in polytherapy.
Andrea E. Cavanna
core   +1 more source

OXCARBAZEPINE-INDUCED TOXIC EPIDERMAL NECROLYSIS: A CASE REPORT [PDF]

, 2012
A 66 year old lady admitted to medical college hospital presented with complaints of skin rashes and itching. Past history of the patient revealed that she was on tablet digoxin and sodium valproate.  Tablet oxcarbazepine was added by a physician one ...
Keshri, Umashanker PD
core   +1 more source

Acute effects of anti‐seizure medications on network level dynamics: A systematic comparison using multielectrode arrays

Epilepsia, EarlyView.
Abstract Objective A multi‐electrode array (MEA) is a powerful extracellular recording technique for long‐term monitoring of neuronal network activity. In recent years, MEA‐based assays have been applied increasingly to evaluate drug efficacy and neurotoxicity, including the assessment of anti‐seizure medications (ASMs). However, systematic comparisons
Griselda Marku, Lena Gschossmann, Kerstin Hallmann, Heinz Beck, Kunihiko Araki   +4 more
wiley   +1 more source

Oxcarbazepine-induced Reversible Pancytopenia and Severe Hyponatremia in a Patient with Bipolar Affective Disorder: Two Case Reports

Journal of Clinical and Diagnostic Research
Oxcarbazepine is a widely used mood stabiliser in Bipolar Affective Disorder (BPAD) due to its favourable tolerability compared with carbamazepine. However, it is associated with serious adverse effects, including hyponatraemia and pancytopenia, which ...
Sowmya Peyouse, S Gopinath, Priya Shivashankar   +2 more
doaj   +1 more source

Long‐term efficacy of adjunctive cenobamate: Open‐label extension of a randomized, placebo‐controlled study in a multinational Asian population

Epilepsia, EarlyView.
Long‐term efficacy and safety of adjunctive cenobamate in a multinational Asian population. Open‐label extension (OLE) efficacy population included all patients who had taken ≥1 dose of study drug and had any seizure data during the OLE maintenance phase.
Sang Kun Lee, Peimin Yu, Eunyeong Choe, Louis Ferrari, Kyoung Heo, Seung Bong Hong, Zhen Hong, Koji Iida, Yong Heui Jeon, Jiwon Jung, Marc Kamin, Kensuke Kawai, Ji Hyun Kim, Myung Won Kim, Xiaorong Liu, Jungshin Park, William Rosenfeld, Takamichi Yamamoto, Dong Zhou, Suiqiang Zhu, Sunita N. Misra   +20 more
wiley   +1 more source

Classifying seizures in practice: Testing the 2025 ILAE framework among clinicians in South Africa

Epilepsia, EarlyView.
Abstract Objective The 2025 International League Against Epilepsy (ILAE) seizure classification introduced a basic version for nonspecialists, but its usability is untested. We evaluated whether a multidisciplinary frontline workforce in South Africa could apply it, how consistently, and whether performance improved after self‐directed exposure ...
Aayesha J. Soni, Sarah Jacobs, Muhammad Ilyaas Amien, Abdullah J. Soni, Faeeza Cassim, Sa'ad Lahri, Naeem Brey, Misha Janse van Rensburg, Avumile Nongogo Futwa, Johnre Els, Keashe Adams, Bilal Irfan, M. Claudia Burbano, Jorge G. Burneo   +13 more
wiley   +1 more source

Oxcarbazepine induced hyponatremia

, 2007
Oxcarbazepine, which is believed to be better than carbamezepine in pharmacokinetic features and efficacy, is a new antiepileptic drug used for partial and generalized tonic-clonic seizure treatment. We have detected a case with hyponatremia related with
Kenan Özcan, Şakir Altunbaşak, Özlem Hergüner, Faruk İncecik   +3 more
core   +1 more source