Results 81 to 90 of about 8,892 (155)

Stiripentol use in Dravet syndrome patients in the USA: Results of a real‐world study

open access: yesEpilepsia Open, Volume 11, Issue 1, Page 200-210, February 2026.
Abstract Objective Dravet syndrome (DS) is a severe developmental and epileptic encephalopathy with a high seizure burden and mortality risk. Stiripentol, one of the first DS‐specific therapies, received FDA approval in 2018 but its real‐world use and impact post‐approval in the USA remain insufficiently characterized.
Elaine Wirrell   +11 more
wiley   +1 more source

Neurodevelopmental features in KCNQ2 developmental and epileptic encephalopathy may have limited associations with KV7.2 dysfunction

open access: yesEpilepsia Open, Volume 11, Issue 1, Page 190-199, February 2026.
Abstract Objective Variants in KCNQ2 encoding the voltage‐gated potassium channel KV7.2 are associated with developmental and epileptic encephalopathy (DEE) of varying severity. This study examined the relationship of KCNQ2 variant dysfunction with the neurodevelopmental phenotype of individuals with KCNQ2‐DEE. Methods A parent‐reported survey gathered
Jessa S. Bidwell   +4 more
wiley   +1 more source

Managing the Complex Intersection Between Substance Use Disorders and Infectious Diseases

open access: yes
JACCP: JOURNAL OF THE AMERICAN COLLEGE OF CLINICAL PHARMACY, Volume 9, Issue 3, March 2026.
Karissa Chow   +4 more
wiley   +1 more source

Efficacy and safety of levetiracetam vs. oxcarbazepine in the treatment of children with epilepsy: a systematic review and meta-analysis

open access: yesFrontiers in Pediatrics
BackgroundLevetiracetam (LEV) and oxcarbazepine (OXC) are new antiseizure medications (ASMs). In recent years, OXC monotherapy is widely used in children with epilepsy; however, no consensus exists on applying LEV monotherapy among children with epilepsy.
Yuanyuan Liu   +3 more
doaj   +1 more source

The influence of multiple-dose oxcarbazepine on the metabolism of single-dose quetiapine. In vivo experiment in rats

open access: yesActa Marisiensis - Seria Medica
Objective: Psychiatric and neurologic disorders are susceptible to polypharmacy having a higher risk of developing drug-drug interactions. Quetiapine, a frequently used atypical antipsychotic, is extensively metabolized by cytochrome P450 3A4 isoenzyme ...
Ciocotișan Iulia-Maria   +3 more
doaj   +1 more source

Anti‐seizure prophylaxis in brain tumors: An Italian survey among epileptologists

open access: yes
Epilepsia Open, Volume 11, Issue 1, Page 376-380, February 2026.
Elena Pasini   +17 more
wiley   +1 more source

Nistagmus Downbeat Nystagmus Due to Oxcarbazepine Intoxication

open access: yesTürk Nöroloji Dergisi, 2009
Downbeat nystagmus is associated primarily with structural lesions of the central nervous system and may be observed as a manifestation of drug intoxication.
Gül Yalçın Çakmaklı   +1 more
doaj  

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