Results 171 to 180 of about 747,150 (312)

AAV NRF2 gene therapy preserves retinal structure and function in rodent models of oxidative damage. [PDF]

Mol Ther
Gardner A, Wang S, Daniels A, Li D, Wu C, Lin L, Hong C, Zhao SR, Born RT, Kruczek K, Weist G, Real LB, Wicks J, Nayal M, Carter A, Ott C, Haurigot V, Cepko CL.   +17 more
europepmc   +2 more sources

Biomarkers of oxidative damage as a tool to investigate frailty syndrome in older women. [PDF]

NPJ Aging
Sepúlveda M, Palomo I, Lagos F, Pardo X, López-Alarcón C, Ávila F, Fuentes E.   +6 more
europepmc   +1 more source

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit, Chiranth K. Nagaraj, Jackson S. Newell, Kim Truc Nguyen, Xilal Y. Rima, Jacob Doon‐Ralls, Eduardo Reátegui, Jeffrey M. Statland, Rabi Tawil, Kevin M. Flanigan, Scott Q. Harper, Nizar Y. Saad   +11 more
wiley   +1 more source

Oxidative stress, inflammation, and DNA damage in multiple organs of mice acutely exposed to amorphous silica nanoparticles

, 2016
Abderrahim Nemmar,1 Priya Yuvaraju,1 Sumaya Beegam,1 Javed Yasin,2 Elsadig E Kazzam,2 Badreldin H Ali3 1Department of Physiology, 2Department of Internal Medicine, College of Medicine and Health Sciences, United Arab Emirates University, Al Ain, UAE ...
Kazzam EE, Beegam S, Ali BH, Nemmar A, Yuvaraju P, Yasin J   +5 more
core  

FAM30A Induces Inflammation and Oxidative Damage in PDLSCs by Targeting miR-424-5p. [PDF]

Int Dent J
Zhi W, Huang L, Kang J, Chu Z, Tu M.
europepmc   +1 more source

A 17 Year Old With Developmental Delay Presenting With Increasing Confusion and Imbalance

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Methylmalonic acidemia is an autosomal recessive genetic disorder primarily caused by defects in methylmalonyl‐CoA mutase and cobalamin (vitamin B12) metabolism. These defects disrupt the tricarboxylic acid cycle and oxidative phosphorylation, leading to the abnormal accumulation of metabolic products such as methylmalonic acid, propionic acid,
Wei Zhao, Yingli Zhang, Hongliang Zheng
wiley   +1 more source

Correction: Dapagliflozin attenuates hypoxia/reoxygenation-caused cardiac dysfunction and oxidative damage through modulation of AMPK. [PDF]

Cell Biosci
Tsai KL, Hsieh PL, Chou WC, Cheng HC, Huang YT, Chan SH.   +5 more
europepmc   +1 more source

Effects of Add‐On Icosapent Ethyl With Standard Treatment on Functional Outcomes and Inflammatory Biomarkers in Acute Ischemic Stroke: A Blinded Randomized Controlled Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Ischemic stroke, a major cause of mortality and long‐term disability, results from the abrupt cessation of cerebral blood flow due to vascular occlusion or rupture. Icosapent Ethyl (EPA‐EE), approved for hypertriglyceridemia, has anti‐inflammatory and antithrombotic properties that may lessen ischemic damage.
Mitra Mahmoudi Meymand, Seyed Hossein Aghamiri, Saeed Mohmammad Soleymani, Shadiyeh Bararpoor Poshkohi, Samaneh Masoudi, Hadi Esmaily   +5 more
wiley   +1 more source

Nimesulide limits kainate-induced oxidative damage in the rat hippocampus

, 2000
Kainate induces a marked expression of cyclooxygenase-2 after its systemic administration. Because cyclooxygenase-2 activity is associated to the production of reactive oxygen species, we investigated the effects of nimesulide, a selective cyclooxygenase-
Candelario-Jalil, Eduardo, Ajamieh, Hussam, Leon, Olga S., Sam, Susana, Martinez, Gregorio   +4 more
core  

The cysteine metabolic regulation through CSE-transsulfuration pathway is essential in iron-induced oxidative damage of heart. [PDF]

Redox Rep
Zhang Y, Xin Y, Zhou J, Yang G, Li S.
europepmc   +1 more source