Results 221 to 230 of about 522,162 (364)

Intracellular Formation of Synthetic Peptide Nanostructures Causes Mitochondrial Disruption and Cell Death in Tumor Spheroids

Advanced Science, EarlyView.
Synthetic peptide nanostructures, formed within cancer cells in response to glutathione, lead to mitochondrial dysfunction and cell death. The nanostructures significantly damage mitochondrial networks, impair cellular respiration, and induce cell death in both 2D cultures and 3D tumor spheroids.
Sarah Chagri, Konrad Maxeiner, Maria J. S. A. Silva, Lisa Förch, Julian Link, Patrick Roth, Raphael Meyer, Jana Fetzer, Anke Kaltbeitzel, Ingo Lieberwirth, Katharina Landfester, Manfred Wagner, David Y.W. Ng, Tanja Weil   +13 more
wiley   +1 more source

Mitochondrial Oxidative Phosphorylation Alterations in Placental Tissues from Early- and Late-Onset Preeclampsia. [PDF]

Int J Mol Sci
Lehenauer T, Jaksch-Bogensperger H, Huber S, Weghuber D, Fischer T, Mayr JA, Kofler B, Neumayer B, Gharehbaghi D, Duggan-Peer M, Brandstetter M, Fazelnia C, Feichtinger RG.   +12 more
europepmc   +1 more source

DNA‐PKcs‐Driven YAP1 Phosphorylation and Nuclear Translocation: a Key Regulator of Ferroptosis in Hyperglycemia‐Induced Cardiac Dysfunction in Type 1 Diabetes

Advanced Science, EarlyView.
In the context of chronic hyperglycemia, a DDR is initiated, leading to the pathological activation of DNA‐PKcs in the diabetic heart. This activated DNA‐PKcs directly interacts with and phosphorylates YAP1 at Thr226, thereby increasing the nuclear expression of YAP1.
Junyan Wang, Xing Chang, Chun Li, Jing Gao, Zhijiang Guo, Haowen Zhuang, Lingjun Wang, Yusheng Huang, Wei Wang, Chao Li, Qingyong He   +10 more
wiley   +1 more source

Heme metabolism mediates RANKL-induced osteoclastogenesis via mitochondrial oxidative phosphorylation. [PDF]

J Bone Miner Res
Qiu H, Jin H, Miao J, Li H, Chen J, Yang X, Chen X, Mullin BH, Chen K, Gu R, Qin A, Wilson SG, Xu J.   +12 more
europepmc   +1 more source

THE INHIBITION OF MITOCHONDRIAL RESPIRATION BY 1,10-PHENANTHROLINE AND 2,2'-BIPYRIDINE AND THE POSSIBLE RELATIONSHIP TO OXIDATIVE PHOSPHORYLATION

, 1958
William C. Yang, Davi Yanasugondha, J. Webb   +2 more
openalex   +1 more source

RECONSTITUTION OF THE DINITROPHENOL-SENSITIVE ATP-ADP EXCHANGE REACTION OF OXIDATIVE PHOSPHORYLATION [PDF]

, 1960
Charles L. Wadkins, Albert L. Lehninger
openalex   +1 more source

PHOSPHORYLATIVE AND NON-PHOSPHORYLATIVE OXIDATION IN ACETOBACTER SUBOXYDANS [PDF]

Journal of Biological Chemistry, 1952
Vernon H. Cheldelin, Tsoo E. King
openaire   +2 more sources

Integrative Multi‐Omics and Routine Blood Analysis Using Deep Learning: Cost‐Effective Early Prediction of Chronic Disease Risks

Advanced Science, EarlyView.
Omicsformer, a deep learning model, integrates multi‐omics and routine blood data to accurately predict risks for nine chronic diseases, including cancer and cardiovascular conditions. Validated using large scale clinical data, it reveals early risk trajectories, advancing personalized medicine and offering a cost‐effective, community‐based solution ...
Zhibin Dong, Pei Li, Yi Jiang, Zhihan Wang, Shihui Fu, Hebin Che, Meng Liu, Xiaojing Zhao, Chunlei Liu, Chenghui Zhao, Qin Zhong, Chongyou Rao, Siwei Wang, Suyuan Liu, Dayu Hu, Dongjin Wang, Juntao Gao, Kai Guo, Xinwang Liu, En Zhu, Kunlun He   +20 more
wiley   +1 more source

Using novel oxidative phosphorylation inhibitors to attenuate drug resistance in human gliomas. [PDF]

EXCLI J
Tsai CK, Lin CY, Chang YL, Yang FC, Chou CH, Huang YC, Hueng DY.   +6 more
europepmc   +1 more source

Studies on the oxidative phosphorylation and acidic secretion of the gastric mucosa and influence of the autonomic denervation on them

, 1958
Tetsuya Kikuchi
openalex   +2 more sources