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Oxidative phosphorylation and aging
Ageing Research Reviews, 2006This review addresses the data that support the presence and contribution of decreased mitochondrial oxidative phosphorylation during aging to impaired cellular metabolism. Aging impairs substrate oxidation, decreases cellular energy production and increases the production of reactive intermediates that are toxic to the cell.
Edward J, Lesnefsky, Charles L, Hoppel
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Australian Journal of Experimental Biology and Medical Science, 1958
Albert L. Lehninger +4 more
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Albert L. Lehninger +4 more
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Oxidative Phosphorylation Disease Diagnosis
Seminars in Neurology, 1999ABSTRACT: Although the mtDNA encodes only 13 polypeptide subunits of the OXPHOS enzymes, approximately 1,000 proteins are estimated to be necessary for proper OXPHOS function. Over the past 10 years a wide variety of adult and pediatric OXPHOS diseases were found to be caused by or associated with mitochondrial DNA (mtDNA) mutations and nuclear DNA ...
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Uncouplers of oxidation phosphorylation
Pharmacology & Therapeutics, 1980Abstract Numerous compounds, covering a broad range of chemical structures, selectively interfere with the mitochondrial mechanism for transforming energy derived from oxidative metabolism into regeneration of ATP. Within some chemical classes, structure-activity correlations have been useful.
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Integrative oncology: Addressing the global challenges of cancer prevention and treatment
Ca-A Cancer Journal for Clinicians, 2022Jun J Mao,, Msce +2 more
exaly
Oxidative photosynthetic phosphorylation
Biochimica et Biophysica Acta, 1958openaire +2 more sources