Results 191 to 200 of about 1,592,981 (302)

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Oxidative potential of PM₁, PM_2.5, and PM₁₀ collected in car and tram tunnels to analyse their impact on public health. [PDF]

Sci Rep
Jakhar R, Styszko K, Samek L, Szramowiat-Sala K.   +3 more
europepmc   +1 more source

Prenatal Exposure to PM2.5 Oxidative Potential and Lung Function in Infants and Preschool- Age Children: A Prospective Study. [PDF]

Environ Health Perspect, 2023
Marsal A, Slama R, Lyon-Caen S, Borlaza LJS, Jaffrezo JL, Boudier A, Darfeuil S, Elazzouzi R, Gioria Y, Lepeule J, Chartier R, Pin I, Quentin J, Bayat S, Uzu G, Siroux V, SEPAGES cohort study group.   +16 more
europepmc   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Inter-continental variability in the relationship of oxidative potential and cytotoxicity with PM_2.5 mass. [PDF]

Nat Commun
Salana S, Yu H, Dai Z, Subramanian PSG, Puthussery JV, Wang Y, Singh A, Pope FD, Leiva G MA, Rastogi N, Tripathi SN, Weber RJ, Verma V.   +12 more
europepmc   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

Tailoring photocatalysts to modulate oxidative potential of anilides enhances para-selective electrochemical hydroxylation. [PDF]

Nat Commun
Zhang J, Yang Z, Liu C, Wan H, Hao Z, Ji X, Wang P, Yi H, Lei A.   +8 more
europepmc   +1 more source

Unraveling the Molecular Mechanisms of Glioma Recurrence: A Study Integrating Single‐Cell and Spatial Transcriptomics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Glioma recurrence severely impacts patient prognosis, with current treatments showing limited efficacy. Traditional methods struggle to analyze recurrence mechanisms due to challenges in assessing tumor heterogeneity, spatial dynamics, and gene networks.
Lei Qiu, Yinjiao Fei, Jiaxuan Ding, Kexin Shi, Jinyan Luo, Yuchen Zhu, Xingjian Sun, Gefei Jiang, Yuandong Cao, Weilin Xu, Shu Zhou   +10 more
wiley   +1 more source

Impact of Asymptomatic Intracranial Hemorrhage on Outcome After Endovascular Stroke Treatment

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Endovascular treatment (EVT) achieves high rates of recanalization in acute large‐vessel occlusion (LVO) stroke, but functional recovery remains heterogeneous. While symptomatic intracranial hemorrhage (sICH) has been well studied, the prognostic impact of asymptomatic intracranial hemorrhage (aICH) after EVT is less certain ...
Shihai Yang, Chengsong Yue, Zhuang Li, Xiaolei Shi, Haoxuan Zhu, Jie Yang, Linyu Li, Jiaxing Song, Shitao Fan, Gaoming Li, Wenzhe Sun, Zhixian Ye, Jiacheng Huang, Dahong Yang, Jinfu Ma, Xu Xu, Zhixi Wang, Lilan Wang, Guojian Liu, Fengli Li, Changwei Guo, Li Qi, Wenjie Zi   +22 more
wiley   +1 more source

Assessing the Oxidative Potential of Outdoor PM_2.5 in Wintertime Fairbanks, Alaska. [PDF]

ACS EST Air
Yang Y, Battaglia MA, Mohan MK, Robinson ES, DeCarlo PF, Edwards KC, Fang T, Kapur S, Shiraiwa M, Cesler-Maloney M, Simpson WR, Campbell JR, Nenes A, Mao J, Weber RJ.   +14 more
europepmc   +1 more source