Results 91 to 100 of about 335,229 (260)

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Effect of Heavy Metal Contamination on Caciotta Cheese Made from Buffalo Milk

Applied Sciences
Cadmium (Cd) and lead (Pb) are environmental contaminants that induce oxidative damage in milk and dairy products. The aim of the study was to evaluate the effect of in vitro administration of Pb and Cd on the oxidative status and antioxidant capacity of
Giulia Grassi, Anna Maria Perna
doaj   +1 more source

On the growth and water oxidation stability of hydrous iridium oxide

EES Catalysis
During HIROF growth on metallic Ir, an anhydrous IrO 2 layer forms on all nanoparticles. As smaller nanoparticles are more oxophilic due to the Gibbs–Thomson effect, IrO 2 is more difficult to reduce. This impedes further oxidation and HIROF formation.
Matej Zlatar, Xianxian Xie, Carlo Franke, Tomáš Hrbek, Zdeněk Krtouš, Tong Li, Ivan Khalakhan, Serhiy Cherevko   +7 more
openaire   +3 more sources

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Antioxidative Status and Meat Quality Traits as Affected by Dietary Supplementation of Finishing Pigs with Natural Phenolics

Antioxidants
This work investigated the effect of a plant-based phenolic supplement on the color, myoglobin forms, lipid oxidation, and antioxidative status of fresh and stored (10 days at 4 °C) meat (Longissimus thoracis et lumborum), as well as the antioxidative ...
Małgorzata Muzolf-Panek, Anita Zaworska-Zakrzewska, Anna Czech, Dariusz Lisiak, Małgorzata Kasprowicz-Potocka   +4 more
doaj   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Investigation of Oil Extracted from Roasted and Unroasted Oats with Use of Chemometrics

Applied Sciences
One of the beneficial components of oats is oil that is rich in fatty acids and has excellent health and technological potential. During thermal processing, the oil is prone to chemical changes, both beneficial and adverse.
Bharani Kumar Palani, Marta Siol, Sina Makouie, Joanna Bryś, Eliza Gruczyńska-Sękowska, Piotr Koczoń   +5 more
doaj   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

Comprehensive Evaluation of the Nutritional Quality of Stored Watermelon Seed Oils

Applied Sciences
The appropriate use of food industry by-products such as watermelon seeds could reduce the problem of food waste, following the “zero waste” concept. Research in recent years suggests that these unused waste products could be a source of nutrients and ...
Marta Siol, Beata Witkowska, Diana Mańko-Jurkowska, Sina Makouie, Joanna Bryś   +4 more
doaj   +1 more source