Results 91 to 100 of about 8,154,296 (346)

Two-Year Mediterranean Diet Intervention Improves Hepatic Health in MASLD Patients

Foods
Background: Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) is one of the leading causes of chronic liver disease, affecting 30% of the global adult population and continuing to rise.
Margalida Monserrat-Mesquida, Cristina Bouzas, Silvia García, David Mateos, Miguel Casares, Lucía Ugarriza, Cristina Gómez, Antoni Sureda, Josep A. Tur   +8 more
doaj   +1 more source

5-Dodecanolide, a Compound Isolated from Pig Lard, Presents Powerful Anti-Inflammatory Properties

Molecules, 2021
Background: Pork lard (PL) is traditionally used as an anti-inflammatory agent. We propose to demonstrate the anti-inflammatory properties of PL, and elucidate which compounds could be responsible for the anti-inflammatory effects.
Xavier Capó, Miquel Martorell, Josep A. Tur, Antoni Sureda, Antoni Pons   +4 more
doaj   +1 more source

Olive polyphenol effects in a mouse model of chronic ethanol addiction [PDF]

, 2017
Objectives Alcohol addiction elicits oxidative imbalance and it is well known that polyphenols possess antioxidant properties. We investigated whether or not polyphenols could confer a protective potential against alcohol-induced oxidative stress ...
Bello, Cristiano, Carito, Valentina, CECCANTI, Mauro, CESTARI, VINCENZO, Coccurello, Roberto, Fiore, Marco, Mancinelli, Rosanna, Natella, Fausta   +7 more
core   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

Impact of Adherence to the Mediterranean Diet on Antioxidant Status and Metabolic Parameters in NAFLD Patients: A 24-Month Lifestyle Intervention Study

Antioxidants
Background: The Mediterranean Diet (MedDiet) is recognized as a healthy dietary pattern. Non-alcoholic fatty liver disease (NAFLD) is characterized by the excessive accumulation of fat in the liver.
Maria Magdalena Quetglas-Llabrés, Margalida Monserrat-Mesquida, Cristina Bouzas, Silvia García, Emma Argelich, Miguel Casares, Lucía Ugarriza, Isabel Llompart, Josep A. Tur, Antoni Sureda   +9 more
doaj   +1 more source

Probiotics as Potential Therapy in the Management of Non-Alcoholic Fatty Liver Disease (NAFLD)

Fermentation, 2023
Background: Non-alcoholic fatty liver disease (NAFLD) is the most common liver disease, the prevalence of which has increased over the years. The management of this pathology is not clear, and a specific pharmacological drug that can treat NAFLD is not ...
Margalida Monserrat-Mesquida, Cristina Bouzas, Catalina M. Mascaró, Silvia Tejada, Antoni Sureda   +4 more
doaj   +1 more source

Oxidative Stress: A Key Modulator in Neurodegenerative Diseases

Molecules, 2019
Oxidative stress is proposed as a regulatory element in ageing and various neurological disorders. The excess of oxidants causes a reduction of antioxidants, which in turn produce an oxidation–reduction imbalance in organisms.
Anju Singh, R. Kukreti, L. Saso, Shrikant Kukreti   +3 more
semanticscholar   +1 more source

Targeting Molecular Mediators of Ferroptosis and Oxidative Stress for Neurological Disorders

Oxidative Medicine and Cellular Longevity, 2022
With the acceleration of population aging, nervous system diseases including Alzheimer’s disease (AD), Parkinson’s disease (PD), Huntington’s disease (HD), anxiety, depression, stroke, and traumatic brain injury (TBI) have become a huge burden on ...
Jing Li, Bowen Jia, Ying Cheng, Yiting Song, Qianqian Li, Chengliang Luo   +5 more
semanticscholar   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Oxidative Stress and Hypertension

Circulation Research, 2021
A link between oxidative stress and hypertension has been firmly established in multiple animal models of hypertension but remains elusive in humans.
K. Griendling, L. Camargo, F. Rios, Rheure Alves-Lopes, A. Montezano, R. Touyz   +5 more
semanticscholar   +1 more source