Results 61 to 70 of about 7,239,011 (299)

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Effects of Regular Exercise on the Biochemical, Oxidative, and Inflammatory Profiles and Quality of Life in Older Spaniards with Metabolic Syndrome

Antioxidants
Metabolic syndrome increases the risk of developing diabetes and cardiovascular disease. The regular practice of physical activity is a crucial factor for healthy aging and for controlling and preventing chronic diseases. To assess the effects of regular
Margalida Monserrat-Mesquida, Maria Magdalena Quetglas-Llabrés, Cristina Bouzas, Silvia García, David Mateos, Lucía Ugarriza, Cristina Gómez, Josep A. Tur, Antoni Sureda   +8 more
doaj   +1 more source

Redox phospholipidomics analysis reveals specific oxidized phospholipids and regions in the diabetic mouse kidney

Redox Biology, 2022
While it is generally accepted that oxidative stress impacts the diabetic kidney and contributes to pathogenesis, there is a substantial lack of knowledge about the molecular entity and anatomic location of a variety of reactive species.
Allison McCrimmon, Sydney Corbin, Bindesh Shrestha, Gregory Roman, Suraj Dhungana, Krisztian Stadler   +5 more
doaj   +1 more source

Biophysical analysis of angiotensin II and amyloid‐β cross‐interaction in aggregation and membrane disruption

FEBS Letters, EarlyView.
Angiotensin II (AngII), a neuropeptide, interacts with amyloid‐β (Aβ), a key player in Alzheimer's disease. This study reveals that AngII reduces Aβ aggregation and membrane disruption in vitro. Biophysical assays and molecular modeling suggest AngII binds disordered Aβ forms, potentially modulating early amyloidogenic events and contributing to ...
Mohsen Habibnia, Eric Catalina‐Hernandez, Maialen Cabrerizo‐Idiazabal, Ramon Barnadas‐Rodríguez, Mario Lopez‐Martin, Alex Peralvarez‐Marin   +5 more
wiley   +1 more source

Two-Year Mediterranean Diet Intervention Improves Hepatic Health in MASLD Patients

Foods
Background: Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) is one of the leading causes of chronic liver disease, affecting 30% of the global adult population and continuing to rise.
Margalida Monserrat-Mesquida, Cristina Bouzas, Silvia García, David Mateos, Miguel Casares, Lucía Ugarriza, Cristina Gómez, Antoni Sureda, Josep A. Tur   +8 more
doaj   +1 more source

Probiotics as Potential Therapy in the Management of Non-Alcoholic Fatty Liver Disease (NAFLD)

Fermentation, 2023
Background: Non-alcoholic fatty liver disease (NAFLD) is the most common liver disease, the prevalence of which has increased over the years. The management of this pathology is not clear, and a specific pharmacological drug that can treat NAFLD is not ...
Margalida Monserrat-Mesquida, Cristina Bouzas, Catalina M. Mascaró, Silvia Tejada, Antoni Sureda   +4 more
doaj   +1 more source

Evaluation of Serum Ceruloplasmin Levels as a Biomarker for Oxidative Stress in Patients With Diabetic Retinopathy [PDF]

, 2021
Gurunadh Satyanarayana, Narendra Kumar Keisham, H.S. Batra, Subrahmanya Murti, Mansur Khan, Sandeep Gupta, Vikram Mahindra   +6 more
openalex   +1 more source

Oxidative Stress and Hypertension

Circulation Research, 2021
A link between oxidative stress and hypertension has been firmly established in multiple animal models of hypertension but remains elusive in humans.
K. Griendling, L. Camargo, F. Rios, Rheure Alves-Lopes, A. Montezano, R. Touyz   +5 more
semanticscholar   +1 more source

Linked dimers of the AAA+ ATPase Msp1 reveal energetic demands and mechanistic plasticity for substrate extraction from lipid bilayers

FEBS Letters, EarlyView.
Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur, Brian Acquaviva, Baylee A. Smith, Nathan Walker, Isabella Walter, Matthew L. Wohlever   +5 more
wiley   +1 more source

Impact of Adherence to the Mediterranean Diet on Antioxidant Status and Metabolic Parameters in NAFLD Patients: A 24-Month Lifestyle Intervention Study

Antioxidants
Background: The Mediterranean Diet (MedDiet) is recognized as a healthy dietary pattern. Non-alcoholic fatty liver disease (NAFLD) is characterized by the excessive accumulation of fat in the liver.
Maria Magdalena Quetglas-Llabrés, Margalida Monserrat-Mesquida, Cristina Bouzas, Silvia García, Emma Argelich, Miguel Casares, Lucía Ugarriza, Isabel Llompart, Josep A. Tur, Antoni Sureda   +9 more
doaj   +1 more source