Results 91 to 100 of about 505,050 (297)
Redox Biology, 2017 Mechanistic basis governing the extreme longevity and developmental quiescence of dauer juvenile, a “non-ageing” developmental variant of Caenorhabditis elegans, has remained largely obscure.
Sin Man Lam +4 more
doaj +1 more source
Nucleic Acids Research, 2017 Phospholipids, such as 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine (PAPC), are the major components of cell membranes. Their exposure to reactive oxygen species creates oxidized phospholipids, which predispose to the development of chronic ...
Suvi M. Kuosmanen +12 more
semanticscholar +1 more source
Oxidized phospholipids—Their properties and interactions with proteins
Biochimica et Biophysica Acta (BBA) - Biomembranes, 2012 Lipids are a highly diverse class of biomolecules, with an average eukaryotic cell estimated as containing at least 100,000 different species. The significance of this diversity is still poorly understood, yet it has become clear that lipids have critical regulatory as well as structural roles, varying from signaling (e.g.
Hermetter, Albin +2 more
openaire +2 more sources
Polyphenol‐Mediated Engineering of Lipid Nanoparticles With Crystalline Mesophases
Advanced Materials, EarlyView.A polyphenol‐mediated strategy enables the one‐step formation of lipid nanoparticles with nonlamellar mesophases, including micellar cubic and hexagonal structures. These highly ordered nanostructures accommodate a wide range of cargos—from metal ions to mRNA—and offer a modular and versatile platform for constructing functional lipid‐based delivery ...
Shiyao Li +9 more
wiley +1 more source
Platelets, 2019 Oxidized low-density lipoprotein (oxLDL) and associated oxidized phosphocholine-headgroup phospholipids (oxPCs) activate blood platelets through ligation of the scavenger receptor CD36.
Martin Berger +8 more
doaj +1 more source
Journal of Lipid Research, 2006 Previous studies from our laboratory and others presented evidence that oxidized 1-palmitoyl-2-arachidonyl-sn-glycero-3-phosphatidylcholine (OxPAPC) and oxidized 1-palmitoyl-2-arachidonyl-sn-glycero-3-phosphatidylethanolamine can inhibit ...
Kimberly A. Walton +6 more
doaj +1 more source
Advanced Materials, EarlyView.The lipid droplet inhibitor (LDI), templated with large‐pore mesoporous silica and functionalized with PKCα C1A and lipase, targets lipid degradation in fatty liver. The LDI maintains stable association with lipid droplets, thereby suppressing their formation and expansion.
Seunghee Kim +12 more
wiley +1 more source
Indian Heart Journal, 2019 Lipoprotein(a) [Lp(a)] is a circulating lipoprotein, and its level is largely determined by variation in the Lp(a) gene (LPA) locus encoding apo(a). Genetic variation in the LPA gene that increases Lp(a) level also increases coronary artery disease (CAD)
Enas A. Enas +4 more
doaj +1 more source
Elevated truncated oxidized phospholipids as a factor exacerbating ALI in the aging lungs
The FASEB Journal, 2018 As mechanisms controlling redox homeostasis become impaired with aging, exaggerated oxidant stress may cause disproportional oxidation of cell membranes and circulating phospholipids (PLs), leading to the formation of truncated oxidized PL products (Tr ...
Y. Ke +7 more
semanticscholar +1 more source
Evaluation of the Mechanisms of Mayonnaise Phospholipid Oxidation
Journal of Oleo Science, 2017 Mayonnaise, which is widely used in foods, is rich in lipids and therefore susceptible to oxidation during the manufacturing process, which can result in loss of quality. Herein, we detected and analyzed phosphatidylcholine hydroperoxide (PCOOH) isomers present in fresh mayonnaise using LC-MS/MS.
Shunji, Kato +7 more
openaire +3 more sources