Results 91 to 100 of about 506,293 (263)

A novel function of lipoprotein [a] as a preferential carrier of oxidized phospholipids in human plasma

Journal of Lipid Research, 2008
Oxidized phospholipids (OxPLs) on apolipoprotein B-100 (apoB-100) particles are strongly associated with lipoprotein [a] (Lp[a]). In this study, we evaluated whether Lp[a] is preferentially the carrier of OxPL in human plasma. The content of OxPL on apoB-
Claes Bergmark, Asheesh Dewan, Alexina Orsoni, Esther Merki, Elizabeth R. Miller, Min-Jeong Shin, Christoph J. Binder, Sohvi Hörkkö, Ronald M. Krauss, M. John Chapman, Joseph L. Witztum, Sotirios Tsimikas   +11 more
doaj   +1 more source

Comprehensive analyses of oxidized phospholipids using a measured MS/MS spectra library[S]

Journal of Lipid Research, 2017
Oxidized phospholipids (OxPLs) are widely held to be associated with various diseases, such as arteriosclerosis, diabetes, and cancer. To characterize the structure-specific behavior of OxPLs and their physiological relevance, we developed a ...
Ryohei Aoyagi, K. Ikeda, Yosuke Isobe, M. Arita   +3 more
semanticscholar   +1 more source

Artificial Symbiosis for Bulk Production of Bacterial Cellulose Composites

Advanced Materials, EarlyView.
Co‐cultivation of the cellulose‐producing bacterium with the microalga enables bulk formation of bacterial cellulose under static incubation, with photosynthetically active oxygen‐generating sites throughout the medium. This symbiotic platform supports 3D cellulosic constructs with geometries dictated by the vessel shape.
Kui Yu, Sing Teng Chua, Ran Zhao, Alyssa Smith, Michael Kühl, Alison G. Smith, Tom Ellis, Silvia Vignolini   +7 more
wiley   +1 more source

Rational Design of Optical Single‐Walled Carbon Nanotube‐Based Nanosensors with Biological Recognition Elements

Advanced Sensor Research, EarlyView.
This Review focuses on assessing and providing perspective on the field of rationally‐designed optical sensors constructed with single‐walled carbon nanotubes. The literature is reviewed and evaluated for SWCNT‐based sensors constructed with biomolecular recognition elements, including proteins, peptides, and oligonucleotides, as well as their methods ...
Amelia K. Ryan, Atara Israel, Maria Celina Stefoni, Catarina Ferraz, Ryan M. Williams   +4 more
wiley   +1 more source

Elevated truncated oxidized phospholipids as a factor exacerbating ALI in the aging lungs

The FASEB Journal, 2018
As mechanisms controlling redox homeostasis become impaired with aging, exaggerated oxidant stress may cause disproportional oxidation of cell membranes and circulating phospholipids (PLs), leading to the formation of truncated oxidized PL products (Tr ...
Y. Ke, P. Karki, Junghyun Kim, Sophia Son, E. Berdyshev, V. Bochkov, A. Birukova, K. Birukov   +7 more
semanticscholar   +1 more source

NARFL Knockout Triggers Ferroptosis‐Driven Vascular Endothelial Dysfunction

Advanced Science, EarlyView.
NARFL is vital for CIA and oxidative stress resistance. NARFL deletion in HPMEC cells, zebrafish, and mice is lethal and rescued by a Ferroptosis inhibitor. NARFL deficiency disrupted its interaction with CIA proteins, decreased aconitase activity, increased IRP1 activity, induced Fe overload, and led to ferroptosis and oxidative stress, resulting in ...
Hui Hu, Jing Luo, Li Yu, Daoxi Qi, Boyu Li, Yating Chen, Chen Wang, Xiaokang Zhang, Wenzheng Guo, Qiyong Lou, Gang Zhai, Yonglin Ruan, Jianfei Huang, Shengchi Shi, Zhan Yin, Fang Zheng   +15 more
wiley   +1 more source

Lipidomic Profiling on Oxidized Phospholipids in Type 2 Diabetes Mellitus Model Zebrafish

Analytical Sciences, 2018
Type 2 diabetes mellitus is a serious metabolic disorder in the world. Oxidative stress, as a key role on the pathogenesis of diabetes, also results in the oxidation of phospholipids.
Zhen Chen, Liqing Zang, Yue Wu, H. Nakayama, Yasuhito Shimada, R. Shrestha, Yaoyao Zhao, Y. Miura, H. Chiba, S. Hui, Norihiro Nishimura   +10 more
semanticscholar   +1 more source

Vm–MSI: a Vancomycin–Antimicrobial Peptide Conjugate Combating Resistant Bacteria and Broadening the Antimicrobial Spectrum

Advanced Science, EarlyView.
A series of vancomycin‐antimicrobial peptide conjugates is synthesized and evaluated to identify the optimal combination. Vm‐MSI, selected from multiple candidates, exhibited potent activity against vancomycin‐resistant and Gram‐negative bacteria by disrupting membranes and inducing oxidative stress, thereby expanding vancomycin's antibacterial ...
Shuangyu Li, Kang Wang, Wenzhuang Shi, Xu Wang, Duxin Li, Yanli Liu, Peng Zhang, Yipeng Wang   +7 more
wiley   +1 more source

Long‐Term Elevated CO2 Improves Soil Health and Rice Yields in Paddy Fields

Advanced Science, EarlyView.
Combining the two longest‐running rice free‐air CO2 enrichment experiments with a global data synthesis, this study demonstrates that long‐term elevated CO2 consistently enhances soil health. In rice paddies, this improvement sustains the CO2 fertilization effect over decades.
Fan Jiang, Wenchao Du, Kees Jan van Groenigen, Josep Peñuelas, Scott X. Chang, Lian Song, Chuang Cai, Yu Wang, Lin Deng, Zhengkun Hu, Weishou Shen, Qicong Wu, Haiyang Yu, Ying Yin, Fuxun Ai, Wei Zhou, Dongming Wang, Jianqiang Sun, Xiaoyuan Yan, Renfang Shen, Jiabao Zhang, Hongyan Guo, Chunwu Zhu   +22 more
wiley   +1 more source

Hyperandrogenemia Induces Trophoblast Ferroptosis and Early Pregnancy Loss in Patients With PCOS via CMA‐Dependent FTH1 Degradation

Advanced Science, EarlyView.
In PCOS patients with hyperandrogenemia, decreased ferritin heavy chain 1 (FTH1) causes Fe2⁺ overload and ferroptosis in trophoblasts. Androgens induce FTH1 protein degradation via AR‐LAMP2A‐mediated chaperone‐mediated autophagy pathway, leading to placental development disruption and early pregnancy loss. Metformin mitigates androgen‐induced placental
Hanjing Zhou, Weijie Yang, Na Liu, Qing Liu, Jiamin Jin, Chenqiong Zhao, Xiaoying Jin, Miao Gui, Haiyan Zhu, Songying Zhang, Yinli Zhang   +10 more
wiley   +1 more source