Results 101 to 110 of about 203,353 (285)

Glycoxidized HDL, HDL enriched with oxidized phospholipids and HDL from diabetic patients inhibit platelet function

, 2015
International audienceCONTEXT:High-density lipoproteins (HDL) possess atheroprotective properties including anti-thrombotic and antioxidant effects. Very few studies relate to the functional effects of oxidized HDL on platelets in type 2 diabetes (T2D ...
Lê, Quang Huy, Soulère, Laurent, Lagarde, Michel, Moulin, Philippe, Ségrestin, Bérénice, Véricel, Evelyne, El Alaoui, Meddy, Guichardant, Michel, Calzada, Catherine   +8 more
core   +1 more source

Lipoprotein(a): An independent, genetic, and causal factor for cardiovascular disease and acute myocardial infarction

Indian Heart Journal, 2019
Lipoprotein(a) [Lp(a)] is a circulating lipoprotein, and its level is largely determined by variation in the Lp(a) gene (LPA) locus encoding apo(a). Genetic variation in the LPA gene that increases Lp(a) level also increases coronary artery disease (CAD)
Enas A. Enas, Basil Varkey, T.S. Dharmarajan, Guillaume Pare, Vinay K. Bahl   +4 more
doaj   +1 more source

Iron‐Tannic Acid Hydrogel Mediated Mild Photothermal Therapy Combined With Ferroptosis Enhances Anti‐Tumor Immunity in Colorectal Cancer

Advanced Science, EarlyView.
An injectable gelatin‐based tannic acid–iron hydrogel with mild photothermal therapy could not only induce immunogenic cell death, but also elicit ferroptosis of both tumor cells and tumor‐associated macrophages, resulting in DC maturation, T‐cell infiltration and down‐regulation of ferroptosis‐sensitive M2‐type TAMs levels.
Yuan Zhu, Xi Yu, Tao Wang, Wanyi Liu, Chang Lu, Jiani Zhong, Yujie He, Wei Li, Kunxi Zhang, Peihao Yin, Zeting Yuan   +10 more
wiley   +1 more source

Inflammatory pain control by blocking oxidized phospholipid-mediated TRP channel activation

Scientific Reports, 2017
Phospholipids occurring in cell membranes and lipoproteins are converted into oxidized phospholipids (OxPL) by oxidative stress promoting atherosclerotic plaque formation.
Beatrice Oehler, Katrin Kistner, Corinna Martin, Jürgen Schiller, Rafaela Mayer, Milad Mohammadi, Reine-Solange Sauer, Milos R. Filipovic, Francisco R. Nieto, Jan Kloka, Diana Pflücke, Kerstin Hill, Michael Schaefer, Marzia Malcangio, Peter W. Reeh, Alexander Brack, Robert Blum, Heike L. Rittner   +17 more
doaj   +1 more source

A novel function of lipoprotein [a] as a preferential carrier of oxidized phospholipids in human plasma

Journal of Lipid Research, 2008
Oxidized phospholipids (OxPLs) on apolipoprotein B-100 (apoB-100) particles are strongly associated with lipoprotein [a] (Lp[a]). In this study, we evaluated whether Lp[a] is preferentially the carrier of OxPL in human plasma. The content of OxPL on apoB-
Claes Bergmark, Asheesh Dewan, Alexina Orsoni, Esther Merki, Elizabeth R. Miller, Min-Jeong Shin, Christoph J. Binder, Sohvi Hörkkö, Ronald M. Krauss, M. John Chapman, Joseph L. Witztum, Sotirios Tsimikas   +11 more
doaj   +1 more source

KINETIC OF PHOSPHOLIPID OXIDATION IN LIPOSOMAL SUSPENSIONS

International Journal of Research in Engineering and Technology, 2014
Fil: Fogar, Ricardo Alejandro. Universidad Nacional del Chaco Austral. Departamento de Ciencias Basicas y Aplicadas. Laboratorio de Industrias Alimentarias Ii; Argentina.
Fogar, Ricardo Alejandro, Romero, Ana María, Doval, Mirtha Marina, Judis, Maria Alicia   +3 more
openaire   +2 more sources

Drought Stress Mediated Changes in Food Crops: Mechanisms and Remediation Strategies

Advanced Science, EarlyView.
This work presents a multi‐scale framework for flavonoid‐mediated drought tolerance in staple food crops, integrating ROS redox regulation, antioxidant defense, rhizosphere microbial interactions, and sustainable agronomic practices. This interdisciplinary model provides core insights to develop climate‐resilient cropping systems and enhance global ...
Xiaoyi Duan, Litao Wang, Tuuli‐Marjaana Koski, Lizhe An, Thomas Efferth, Yujie Fu   +5 more
wiley   +1 more source

Oxidized phospholipids induce phase separation in lipid vesicles [PDF]

, 2005
The thermal behaviour of phospholipid multilamellar vesicles (MLV) made of various molar percentages of DPPC and LPPC, containing also oxidized LPPC (LPPCox), was studied by use of EPR spectroscopy and n-DSPC spin label in order to determine variations ...
Sabatini, Karen, Karen Sabatini, Francesco M. Megli, Luciana Russo, Megli, Francesco M., Russo, Luciana   +5 more
core   +1 more source

Supramolecular Degraders: An Emerging Paradigm in Targeted Protein Degradation

Advanced Science, EarlyView.
Dynamic supramolecular assembly reshapes targeted protein degradation by coordinating modular degrader construction, delivery, functional integration, and intracellular assembly or activation across proteasomal, endosomal–lysosomal, and autophagy–lysosomal pathways.
Kongjun Liu, Xue Yuan, Yan Zhou, Rui Yuan, Shaocheng Xie, Yong Chen, Peiyi Wang, Jianmei Gao, Qihai Gong   +8 more
wiley   +1 more source

Structural Basis for the Recognition of Oxidized Phospholipids in Oxidized Low Density Lipoproteins by Class B Scavenger Receptors CD36 and SR-BI

, 2010
Specific oxidized phospholipids (oxPCCD36) accumulate in vivo at sites of oxidative stress and serve as high affinity ligands for scavenger receptors class B (CD36 and SR-BI).
Kar, Niladri S., Sayre, Lawrence M., Gao, Detao, Ashraf, Mohammad Z., Podrez, Eugene A., Lin, De   +5 more
core   +1 more source