Results 101 to 110 of about 655,979 (316)

Total oxylipin concentrations in NIST SRM 1950 plasma compared to fresh and commercially obtained human plasma

Journal of Lipid Research
Oxylipins are oxidized PUFAs such as hydroxy-PUFAs and epoxy-PUFAs. Total oxylipins are commonly analyzed following base hydrolysis as nonesterified oxylipins by means of LC-MS/MS.
Nadja Kampschulte, Lilli Scholz, Theresa L. Pedersen, Isabel F. Snodgrass, John W. Newman, Nils Helge Schebb   +5 more
doaj   +1 more source

Normal high density lipoprotein inhibits three steps in the formation of mildly oxidized low density lipoprotein: step 1

Journal of Lipid Research, 2000
Apolipoprotein A-I (apoA-I) and an apoA-I peptide mimetic removed seeding molecules from human low density lipoprotein (LDL) and rendered the LDL resistant to oxidation by human artery wall cells.
Mohamad Navab, Susan Y. Hama, C. Justin Cooke, G.M. Anantharamaiah, Manjula Chaddha, Linda Jin, Ganesamoorthy Subbanagounder, Kym F. Faull, Srinivasa T. Reddy, Norman E. Miller, Alan M. Fogelman   +10 more
doaj   +1 more source

Oxpholipin 11D: an anti-inflammatory peptide that binds cholesterol and oxidized phospholipids. [PDF]

PLoS ONE, 2010
Many gram-positive bacteria produce pore-forming exotoxins that contain a highly conserved, 12-residue domain (ECTGLAWEWWRT) that binds cholesterol. This domain is usually flanked N-terminally by arginine and C-terminally by valine.
Piotr Ruchala, Mohamad Navab, Chun-Ling Jung, Susan Hama-Levy, Ewa D Micewicz, Hai Luong, Jonathan E Reyles, Shantanu Sharma, Alan J Waring, Alan M Fogelman, Robert I Lehrer   +10 more
doaj   +1 more source

Enzymatically oxidized phospholipids restore thrombin generation in coagulation factor deficiencies

JCI Insight, 2018
Hemostatic defects are treated using coagulation factors; however, clot formation also requires a procoagulant phospholipid (PL) surface.
David A. Slatter, K. Allen-Redpath, Joshua M. Gajsiewicz, Aled Tyrrell Nick J Clayton, Yoel Garcia-Diaz, M. Judith, Charles L. Percy, Nickolas J Brooks, A. Clayton, V. Tyrrell, Marcela Rosas, Sarah N. Lauder, A. Watson, M. Dul, Yoel Garcia-Diaz, Maceler Aldrovandi, M. Heurich, J. Hall, James H. Morrissey, S. Lacroix-Desmazes, S. Delignat, P. V. Jenkins, Peter W. Collins, Valerie B. O’Donnell   +23 more
semanticscholar   +1 more source

Thermo‐Fluorescent Bactericidal Quantum Dots Based Smart Multifunctional Textiles via Molecular Surface Engineering and 3D‐Printed Interlocked Architectures

Advanced Healthcare Materials, EarlyView.
A versatile approach is presented for fabricating smart multifunctional textiles by integrating thermo‐fluorescent carbon dot/polymer nanocomposite coatings with 3D‐printed interlocked architectures. The fabrics exhibit temperature‐responsive fluorescence, durable hydrophobicity, strong antibacterial and antioxidant activity, and enhanced UV protection.
Poushali Das, Sayan Ganguly, Parham Khoshbakht Marvi, Misha Muthalali, Fatemeh Parniani, Shiza Hassan, Xiaowu (Shirley) Tang, Seshasai Srinivasan, Amin Reza Rajabzadeh   +8 more
wiley   +1 more source

Normal high density lipoprotein inhibits three steps in the formation of mildly oxidized low density lipoprotein: steps 2 and 3

Journal of Lipid Research, 2000
Treatment of human artery wall cells with apolipoprotein A-I (apoA-I), but not apoA-II, with an apoA-I peptide mimetic, or with high density lipoprotein (HDL), or paraoxonase, rendered the cells unable to oxidize low density lipoprotein (LDL).
Mohamad Navab, Susan Y. Hama, G.M. Anantharamaiah, Kholood Hassan, Greg P. Hough, Andrew D. Watson, Srinivasa T. Reddy, Alex Sevanian, Gregg C. Fonarow, Alan M. Fogelman   +9 more
doaj   +1 more source

NRF2 regulates endothelial glycolysis and proliferation with miR-93 and mediates the effects of oxidized phospholipids on endothelial activation

Nucleic Acids Research, 2017
Phospholipids, such as 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine (PAPC), are the major components of cell membranes. Their exposure to reactive oxygen species creates oxidized phospholipids, which predispose to the development of chronic ...
Suvi M. Kuosmanen, E. Kansanen, M. Kaikkonen, Virve Sihvola, K. Pulkkinen, H. Jyrkkänen, Pauli Tuoresmäki, J. Hartikainen, M. Hippeläinen, H. Kokki, P. Tavi, S. Heikkinen, A. Levonen   +12 more
semanticscholar   +1 more source

Nanotherapies for Atherosclerosis: Targeting, Catalysis, and Energy Transduction

Advanced Healthcare Materials, EarlyView.
Atherosclerosis management is hindered by poor drug targeting and plaque heterogeneity. Nanotechnology overcomes these barriers via three core strategies: (1) target‐engineered nanocarriers that achieve lesion‐specific precision via ligand modification, biomimetic camouflage, stimuli‐responsive release, and self‐propelling nanomotors; (2) catalytic ...
Yuqi Yang, Jingguo Qu, Tonghuan Xiao, Xinyang Han, Michael Tin‐Cheung Ying   +4 more
wiley   +1 more source

CoQ10 and Aging. [PDF]

, 2019
The aging process includes impairment in mitochondrial function, a reduction in anti-oxidant activity, and an increase in oxidative stress, marked by an increase in reactive oxygen species (ROS) production.
Barcelos, Isabella Peixoto de, Haas, Richard H   +1 more
core   +1 more source

A novel role for NUPR1 in the keratinocyte stress response to UV oxidized phospholipids

Redox Biology, 2018
Ultraviolet light is the dominant environmental oxidative skin stressor and a major skin aging factor. We studied which oxidized phospholipid (OxPL) mediators would be generated in primary human keratinocytes (KC) upon exposure to ultraviolet A light ...
M. Narzt, I. Nagelreiter, O. Oskolkova, V. Bochkov, J. Latreille, M. Fedorova, Z. Ni, Fernando J. Sialana, G. Lubec, M. Filzwieser, M. Laggner, M. Bilban, M. Mildner, E. Tschachler, J. Grillari, F. Gruber   +15 more
semanticscholar   +1 more source