Results 21 to 30 of about 506,293 (263)

Reduction of myocardial ischaemia–reperfusion injury by inactivating oxidized phospholipids [PDF]

Cardiovasc Res, 2018
Aims Myocardial ischaemia followed by reperfusion (IR) causes an oxidative burst resulting in cellular dysfunction. Little is known about the impact of oxidative stress on cardiomyocyte lipids and their role in cardiac cell death.
C. Yeang, D. Hasanally, X. Que, Ming-Yow Hung, A. Stamenković, David Chan, R. Chaudhary, V. Margulets, A. Edel, M. Hoshijima, Yusu Gu, W. Bradford, N. Dalton, Phuong Miu, D. Cheung, D. Jassal, G. Pierce, K. Peterson, L. Kirshenbaum, J. Witztum, S. Tsimikas, A. Ravandi   +21 more
semanticscholar   +2 more sources

Oxidized phospholipids are ligands for LRP6 [PDF]

Bone Res, 2018
Low-density lipoprotein receptor–related protein 6 (LRP6) is a co-receptor for Wnt signaling and can be recruited by multiple growth factors/hormones to their receptors facilitating intracellular signaling activation.
Lei Wang, Yu Chai, Changjun Li, Haiyun Liu, Weiping Su, Xiaonan Liu, Bing-Fang Yu, Weiqi Lei, Bin Yu, Janet L. Crane, Xu Cao, M. Wan   +11 more
semanticscholar   +2 more sources

Lp(a), oxidized phospholipids and oxidation-specific epitopes are increased in subjects with keloid formation. [PDF]

Lipids Health Dis, 2022
Ruder S, Mansfield B, Immelman AR, Varki N, Miu P, Raal F, Tsimikas S.   +6 more
europepmc   +3 more sources

Lipoprotein(a), Oxidized Phospholipids, and Aortic Valve Microcalcification Assessed by 18F-Sodium Fluoride Positron Emission Tomography and Computed Tomography [PDF]

CJC Open, 2019
Audrey-Anne Després, N. Perrot, A. Poulin, L. Tastet, Mylène Shen, H. Chen, Raphaëlle Bourgeois, M. Trottier, M. Tessier, J. Guimond, Maxime Nadeau, J. Engert, S. Thériault, Y. Bossé, J. Witztum, P. Couture, P. Mathieu, M. Dweck, S. Tsimikas, G. Thanassoulis, P. Pibarot, M. Clavel, B. Arsenault   +22 more
semanticscholar   +2 more sources

Lipoprotein(a) and Oxidized Phospholipids Promote Valve Calcification in Patients With Aortic Stenosis [PDF]

J Am Coll Cardiol, 2019
K. Zheng, S. Tsimikas, T. Pawade, J. Kroon, W. Jenkins, M. Doris, A. White, N. Timmers, J. Hjortnaes, M. Rogers, E. Aikawa, B. Arsenault, J. Witztum, D. Newby, M. Koschinsky, Z. Fayad, E. Stroes, S. Boekholdt, M. Dweck   +18 more
semanticscholar   +2 more sources

Neutralization of Oxidized Phospholipids Ameliorates Non-alcoholic Steatohepatitis. [PDF]

Cell Metab, 2019
Xiaoli Sun, J. Seidman, Peng Zhao, T. Troutman, N. Spann, X. Que, Fangli Zhou, Z. Liao, M. Pasillas, Xiaohong Yang, Jason Magida, T. Kisseleva, D. Brenner, M. Downes, R. Evans, A. Saltiel, S. Tsimikas, C. Glass, J. Witztum   +18 more
semanticscholar   +2 more sources

Evaluation of antioxidant property of heat shock protein 90 from duck muscle [PDF]

Animal Bioscience, 2021
Objective The objectives of this study were to investigate the direct antioxidative effect of 90 Kda heat shock protein (Hsp90) obtained from duck muscle.
Muhan Zhang, Daoying Wang, Xinglian Xu, Weimin Xu   +3 more
doaj   +1 more source

Oxidized phospholipids are biomarkers, drug targets, and drug leads

Frontiers in Drug Discovery, 2022
Enzymatic oxidation or autooxidation of esterified polyunsaturated fatty acids (PUFA) residues within phospholipids in cell membranes or circulating lipoprotein particles leads to the formation of a broad range of oxidized phospholipid (OxPL) species ...
O. Oskolkova, A. Birukova, K. Birukov, V. Bochkov   +3 more
semanticscholar   +1 more source

In Vitro Digestion of Grape Seed Oil Inhibits Phospholipid-Regulating Effects of Oxidized Lipids

Biomolecules, 2020
The intake of dietary lipids is known to affect the composition of phospholipids in gastrointestinal cells, thereby influencing passive lipid absorption.
Sarah Fruehwirth, Sofie Zehentner, Mohammed Salim, Sonja Sterneder, Johanna Tiroch, Barbara Lieder, Martin Zehl, Veronika Somoza, Marc Pignitter   +8 more
doaj   +1 more source

Altered activities of anti-atherogenic enzymes LCAT, paraoxonase, and platelet-activating factor acetylhydrolase in atherosclerosis-susceptible mice

Journal of Lipid Research, 2002
We examined whether the putative anti-atherogenic enzymes LCAT, paraoxonase (PON), and platelet-activating factor acetylhydrolase (PAF-AH) are impaired in 8 week old atherosclerosis susceptible apolipoprotein E (apoE)−/− and LDL receptor (LDLr)−/− mice ...
Trudy M. Forte, Ganesamoorthy Subbanagounder, Judith A. Berliner, Patricia J. Blanche, Anne O. Clermont, Zhen Jia, Michael N. Oda, Ronald M. Krauss, John K. Bielicki   +8 more
doaj   +1 more source