Results 211 to 220 of about 43,837 (307)

Biochemical and structural characterization of chlorite dismutase enzyme from Pseudomonas aeruginosa

open access: yesThe FEBS Journal, EarlyView.
Chlorite dismutase (Cld) is a heme b oxidoreductase that can decompose chlorite (ClO2−$$ {\mathrm{ClO}}_2^{-} $$ or OClO−) into harmless chloride (Cl−) and dioxygen (O2) with high turnover rates. Cld was found to be involved in different biological processes, and the rare reaction it catalyzes makes it a prominent enzyme for different applications. The
Dimitrios V. Nokas   +7 more
wiley   +1 more source

Studies of the membrane‐bound flavocytochrome MsrQ flavin mononucleotide (FMN)‐binding site reveal an unexpected ubiquinone cofactor

open access: yesThe FEBS Journal, EarlyView.
The membrane‐bound heme flavoprotein MsrQ is the specific electron donor for the periplasmic methionine sulfoxide reductase MsrP. Analysis of its flavin environment revealed that ubiquinone (UQ) is a cofactor for MsrQ. However, redox studies demonstrate that UQ cannot function as an electron donor for the MsrPQ system.
Philippe Carpentier   +9 more
wiley   +1 more source

Structure, mechanism, and evolution of the last step in vitamin C biosynthesis. [PDF]

open access: yesNat Commun
Boverio A   +5 more
europepmc   +1 more source

Sex‐dimorphic gene regulation in murine macrophages across niches

open access: yesImmunology &Cell Biology, EarlyView.
In this study, we perform a meta‐analysis of new and publicly available RNA‐seq datasets from male and female mouse macrophages across eight niches to identify conserved sex‐dimorphic gene expression patterns. We found that three sex chromosome‐linked genes are always differentially expressed between males and females: Ddx3y, Eif2s3y and Xist. However,
Cassandra J McGill   +4 more
wiley   +1 more source

Hyperuricaemia in type 1 Gaucher disease: is uric acid a biomarker for disease severity?

open access: yesInternal Medicine Journal, EarlyView.
Abstract Background Elevated serum uric acid (SUA) levels were observed in Gaucher disease type 1 (GD1) patients followed for two decades in northern Israel. There are no previous reports regarding hyperuricaemia in GD1 patients. Aims We aimed to evaluate the frequency of hyperuricaemia in GD1 patients and its correlation to disease severity ...
Zufit Hexner‐Erlichman   +4 more
wiley   +1 more source

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