Results 21 to 30 of about 47,946 (259)

The Origin of Stereoselectivity in the Hydrogenation of Oximes Catalyzed by Iridium Complexes: A DFT Mechanistic Study

Molecules, 2022
Herein the reaction mechanism and the origin of stereoselectivity of asymmetric hydrogenation of oximes to hydroxylamines catalyzed by the cyclometalated iridium (III) complexes with chiral substituted single cyclopentadienyl ligands (Ir catalysts A1 and
Qaim Ali, Yongyong Chen, Ruixue Zhang, Zhewei Li, Yanhui Tang, Min Pu, Ming Lei   +6 more
doaj   +1 more source

Microwave Assisted Synthesis of Py-Im Polyamides [PDF]

, 2012
Microwave synthesis was utilized to rapidly build Py-Im polyamides in high yields and purity using Boc-protection chemistry on Kaiser oxime resin. A representative polyamide targeting the 5′-WGWWCW-3′ (W = A or T) subset of the consensus Androgen and ...
Bacsa B., Baird E. E., Bando T., Baptiste B., Chenoweth D. M., Chenoweth D. M., Chenoweth D. M., Choi J. S., Dale J. A., DeGrado W. F., Dervan P. B., Dervan P. B., Dose C., Edelson B. S., Farnham P. J., Harki D. A., Harris D., James W. Puckett, Joshua T. Green, Kappe C. O., Krutzik P. O., König B., Lai Y.-M., Murray J. K., Muzikar K. A., Nickols N. G., Olenyuk B. Z., Olivos H. J., Palasek S. A., Pelton J. G., Peter B. Dervan, Raskatov J. A., Sinyakov A. N., Su W., Turner J. M., Wade W. S., White S., Wurtz N. R., Xiao J. H.   +38 more
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Formaldehyde Oxime ⇌ Nitrosomethane Tautomerism. [PDF]

The Journal of Organic Chemistry, 2001
Formaldehyde oxime nitrosomethane tautomerism, isomeric nitrone, and their common cations and anions are studied with Gaussian-2 theory using MP2(full)/6-31G geometries and with density functional theory using B3LYP/6-311+G**. Geometrical parameters, harmonic vibrational frequencies, relative stabilities, conformational stabilities, and ionization ...
Long, J.A., Harris, N.J., Lammertsma, K.
openaire   +2 more sources

Experimental and Computational Investigation of the Oxime Bond Stereochemistry in c-Jun N-terminal Kinase 3 Inhibitors 11H-Indeno[1,2-b]quinoxalin-11-one Oxime and Tryptanthrin-6-oxime

Pharmaceutics, 2023
11H-Indeno[1,2-b]quinoxalin-11-one oxime (IQ-1) and tryptanthrin-6-oxime are potent c-Jun N-terminal kinase 3 (JNK-3) inhibitors demonstrating neuroprotective, anti-inflammatory and anti-arthritic activity.
Vladislava V. Matveevskaya, Dmitry I. Pavlov, Anastasia R. Kovrizhina, Taisiya S. Sukhikh, Evgeniy H. Sadykov, Pavel V. Dorovatovskii, Vladimir A. Lazarenko, Andrei I. Khlebnikov, Andrei S. Potapov   +8 more
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The Development of a Direct Homologous Radioimmunoassay for Serum Cortisol [PDF]

, 1981
Peer ...
Giesemann, G., Müller, O. A., Scriba, Peter Christian, Stalla, G., Wood, W. G.   +4 more
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The Evaluation of the Reactivating and Neuroprotective Efficacy of Two Newly Prepared Bispyridinium Oximes (K305, K307) in Tabun-Poisoned Rats—A Comparison with Trimedoxime and the Oxime K203

Molecules, 2017
The ability of two newly developed oximes (K305, K307) to protect tabun-poisoned rats from tabun-induced inhibition of brain acetylcholinesterase, acute neurotoxic signs and symptoms and brain damage was compared with that of the oxime K203 and ...
Jiri Kassa, Jan Misik, Jana Hatlapatkova, Jana Zdarova Karasova, Vendula Sepsova, Filip Caisberger, Jaroslav Pejchal   +6 more
doaj   +1 more source

PHOSPHORYLPHOSPHATASE AND OXIMES [PDF]

British Journal of Pharmacology and Chemotherapy, 1961
The effects of pralidoxime iodide, 1,1‐trimethylenebis(4‐formylpyridinium bromide) dioxime and diacetyl monoxime on the activity of phosphorylphosphatase prepared from pig kidney in vitro have been studied. It was found that these oximes, even at high concentrations, did not affect the activity of the enzyme.
H, EDERY, G, SCHATZBERG-PORATH
openaire   +2 more sources

Pyridinium-2-carbaldoximes with quinolinium carboxamide moiety are simultaneous reactivators of acetylcholinesterase and butyrylcholinesterase inhibited by nerve agent surrogates

Journal of Enzyme Inhibition and Medicinal Chemistry, 2021
The pyridinium-2-carbaldoximes with quinolinium carboxamide moiety were designed and synthesised as cholinesterase reactivators. The prepared compounds showed intermediate-to-high inhibition of both cholinesterases when compared to standard oximes. Their
Hyun Myung Lee, Rudolf Andrys, Jakub Jonczyk, Kyuneun Kim, Avinash G. Vishakantegowda, David Malinak, Adam Skarka, Monika Schmidt, Michaela Vaskova, Kamil Latka, Marek Bajda, Young-Sik Jung, Barbara Malawska, Kamil Musilek   +13 more
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Novel Tryptanthrin Derivatives with Selectivity as c–Jun N–Terminal Kinase (JNK) 3 Inhibitors

Molecules, 2023
The c-Jun N-terminal kinase (JNK) family includes three proteins (JNK1-3) that regulate many physiological processes, including cell proliferation and differentiation, cell survival, and inflammation.
Igor A. Schepetkin, Oleksander S. Karpenko, Anastasia R. Kovrizhina, Liliya N. Kirpotina, Andrei I. Khlebnikov, Stepan I. Chekal, Alevtyna V. Radudik, Maryna O. Shybinska, Mark T. Quinn   +8 more
doaj   +1 more source

A comparative study of the electrochemical properties of vitamin B-6 related compounds at physiological pH [PDF]

, 2011
A comparative study of vitamin B6 group and related compounds in buffered solutions using electrochemical techniques has been performed at neutral pH.
A. Pocker, A. Temizer, A.E. Braunstein, A.J. Bard, A.J. Román, A.K. Lunn, C.M. Harris, C.M. Metzler, D. Manousek, E.E. Snell, H. Lund, J. Gonzalez-Rodríguez, J. Llor, J. Llor, J. M. Sevilla, J.M. Rodríguez Mellado, J.M. RodrÍguez Mellado, J.M. RodrÍguez Mellado, J.M. RodrÍguez Mellado, L. Camacho, M. Blázquez, M. Blázquez, M. Heyrovský, M. Stanulovic, M.L. Ahrens, M.S. Ibrahim, N.P. Bazhulina, P. Zuman, P. Zuman, R. Izquierdo, R. Izquierdo, R. Schwartz, S.G. Mairanoskii, T. Pineda, T. Pineda, T. Pineda, V. Mirceski, W.F. Wolkers, Y.V. Morozov   +38 more
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