Results 71 to 80 of about 8,623 (211)

2′-Methyl-2′-nitro-1′-phenyl-2′,3′,5′,6′,7′,7a'-hexahydrospiro[indoline-3,3′-1′H-pyrrolizin]-2-one

Acta Crystallographica Section E, 2008
The title compound, C21H21N3O3, was synthesized by a multi-component 1,3-dipolar cycloaddition of azomethine ylide, derived from isatin and proline by a decarboxylative route, and (E)-1-phenyl-2-nitropropene.
Yaghoub Sarrafi, Kamal Alimohammadi
doaj   +1 more source

Diethyl 1-acetyl-4′-(4-chlorophenyl)-5′-(4-nitrophenyl)-2-oxospiro[indoline-3,3′-pyrrolidine]-2′,2′-dicarboxylate

Acta Crystallographica Section E, 2009
In the title compound, C31H28ClN3O8, the pyrrolidine ring exhibits an envelope conformation, with the spiro C atom located at the flap position. A spiro junction links the oxindole ring system and the pyrrolidine ring.
Long He
doaj   +1 more source

Synthesis of spiro[dihydropyridine-oxindoles] via three-component reaction of arylamine, isatin and cyclopentane-1,3-dione

Beilstein Journal of Organic Chemistry, 2013
A fast and convenient protocol for the synthesis of novel spiro[dihydropyridine-oxindole] derivatives in satisfactory yields was developed by the three-component reactions of arylamine, isatin and cyclopentane-1,3-dione in acetic acid at room temperature.
Yan Sun, Jing Sun, Chao-Guo Yan
doaj   +1 more source

An Efficient Synthesis of a Spirocyclic Oxindole Analogue

Molecules, 2006
An efficient, scaleable synthesis approach towards the spirocyclic oxindole analogue 1’-(tert-butoxycarbonyl)-2-oxospiro[indoline-3,4’-piperidine]-5-carboxylic acid (1) is described. The key steps are dianion alkylation and cyclization of ethyl
A. Mendonca, Hongxing Zhang, Dawei Teng
doaj   +1 more source

Spirofused Tetrahydroisoquinoline-Oxindole Hybrids (Spiroquindolones) as Potential Multitarget Antimalarial Agents: Preliminary Hit Optimization and Efficacy Evaluation in Mice

, 2022
Noella Molisa Efange, Maloba M. M. Lobe, Lauve Rachel Tchokouaha Yamthé, Jeannette Nina Magoudjou Pekam, Protus Arrey Tarkang, Lawrence Ayong, Simon M. N. Efange   +6 more
openalex   +2 more sources

Auxin activity of 3-hydroxymethyl oxindole and 3-methylene oxindole in oat

Biologia Plantarum, 1986
Two photooxidation products of indol-3-ylacetic acid (IAA), 3-hydroxymethyl oxindole (HMO) and 3-methylene oxindole (Meox) were almost as effective as IAA in stimulation of growth of oat (Avena saliva cv. Kent) coleoptile sections. The IAA failed to give stimulation of growth after pretreatment of the coleoptiles with chemicals inhibiting oxidation of ...
R. N. Bhattacharyya, K. K. Chattopadhyay, P. S. Basu   +2 more
openaire   +1 more source

Treatment with 5-fluoro-2-oxindole Increases the Antinociceptive Effects of Morphine and Inhibits Neuropathic Pain

, 2020
Pablo Ferreira-Chamorro, Alejandro Redondo, Gabriela Riego, Olga Pol   +3 more
openalex   +2 more sources

Unexpected regioselective carbon–hydrogen bond activation/cyclization of indolyl aldehydes or ketones with alkynes to benzo-fused oxindoles [PDF]

, 2014
Xingyan Liu, Gaocan Li, Feijie Song, Jingsong You   +3 more
openalex   +1 more source

Identification of potential biological targets of oxindole scaffolds via in silico repositioning strategies [PDF]

, 2022
Annachiara Tinivella, Luca Pinzi, Guido Gambacorta, Ian R. Baxendale, Giulio Rastelli   +4 more
openalex   +1 more source

The Oxindole Derivatives, New Promising GSK-3β Inhibitors as One of the Potential Treatments for Alzheimer’s Disease—A Molecular Dynamics Approach [PDF]

, 2021
Przemysław Czeleń, Beata Szefler
openalex   +1 more source