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Genome-wide analysis of cytochrome P450 genes discovers two oxidases responsible for the biosynthesis of oxindole alkaloids in Uncaria rhynchophylla

Industrial Crops and Products
Uncaria rhynchophylla (Gou-teng, UR) produces numerous structurally diverse tetracyclic monoterpene oxindole-type alkaloids (tMOAs) with notable pharmacological activities. Cytochromes P450 (CYPs) play crucial roles in generating the structural diversity
Hao-cheng Lou +8 more
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Enhancing anticancer activity of spiropyrazoline oxindoles by disrupting p53-MDMs PPIs

, 2019
Maria M. M. Santos +4 more
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Molecular diversity of the reactions of MBH carbonates of isatins and various nucleophiles

Beilstein Journal of Organic Chemistry
In this paper, the nucleophilic substitution reactions of various N- and P-containing nucleophiles to MBH carbonates of isatins were investigated. Diverse functionalized 3-substituted oxindole derivatives were successfully prepared in satisfactory yields
Zi-Ying Xiao, Jing Sun, Chao-Guo Yan
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Oxindoles. V. Selective Solvolysis Reactions of Oxindole-Spirodimer