Results 11 to 20 of about 2,987 (182)
Catalytic Enantioselective Fluorination of Oxindoles [PDF]
Journal of the American Chemical Society, 2005 AbstractFor Abstract see ChemInform Abstract in Full Text.
Mikiko Sodeoka
exaly +3 more sources
tert-Butyl Hypochlorite: A Reagent for the Synthesis of Chlorinated Oxindole and Indole Derivatives [PDF]
Moleculestert-Butyl hypochlorite was employed as a versatile reagent for chlorooxidation of indoles, chlorination of 2-oxindoles, and decarboxylative chlorination of the indole-2-carboxylic acids.
Chun-Yan Liu +4 more
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Preparation of spirocyclic oxindoles by cyclisation of an oxime to a nitrone and dipolar cycloaddition [PDF]
Beilstein Journal of Organic ChemistryOxindoles are an important class of compounds with significant biological activities. Spirocyclic derivatives are present in a variety of natural products.
Beth L. Ritchie +2 more
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Enantioselective de novo construction of 3‑oxindoles via organocatalyzed formal [3 + 2] annulation from simple arylamines [PDF]
Nature CommunicationsThe de novo construction of enantioenriched 3-hydroxyindolenines and 3-oxindoles from easily available starting materials has been highly desired. Herein, an enantioselectively intermolecular direct [3 + 2] annulation of aryl amine with 2,3-diketoesters ...
Yong Wang +6 more
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Re-design and evaluation of diclofenac-based carborane-substituted prodrugs and their anti-cancer potential [PDF]
Scientific ReportsIn this study, we investigated a novel anti-cancer drug design approach by revisiting diclofenac-based carborane-substituted prodrugs. The redesigned compounds combine the robust carborane scaffold with the oxindole framework, resulting in four carborane-
Christoph Selg +13 more
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Regioselective Synthesis of Spiro-Oxindoles via a Ruthenium-Catalyzed Metathesis Reaction
Chemistry Proceedings, 2023 Spiro-oxindoles are important heterocyclic motifs found in various alkaloids, many of which exhibit pharmacological properties. Due to the remarkable biological activity of spiro-oxindoles, significant effort has been made towards the synthesis of ...
Pradip Debnath
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Molecules, 2022 Carbonyl-containing oxindoles are ubiquitous core structures present in many biologically active natural products and pharmaceutical molecules. Nickel-catalyzed reductive aryl-acylation of alkenes using aryl anhydrides or alkanoyl chlorides as acyl ...
Zhengtian Ding, Wangqing Kong
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Synthesis of 2-oxindoles via visible-light photoredox catalysis
Nantong Daxue xuebao. Ziran kexue ban, 2022 To develop an effective synthetic method for the preparation of 2-oxindoles, using readily available N-aryl acrylamides and diethyl bromomalonate as starting materials, and visible light as green and sustainable energy source,the synthesis of various ...
WANG Pengfei; YI Wei; LIU Gongqing
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SynOpen, 2023 A direct oxidative alkylarylation reaction of N-arylacrylamides with simple alkanes for the synthesis of 3,3-disubstituted oxindoles under metal-free conditions was demonstrated.
Yan Chen +6 more
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Frontiers in Molecular Biosciences, 2021 In this review we compare and discuss results of compounds already reported as anticancer agents based on isatin-derivatives, metalated as well as non-metallated.
Raphael Enoque Ferraz de Paiva +4 more
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