Results 21 to 30 of about 2,987 (182)
A nickel phosphide nanoalloy catalyst for the C-3 alkylation of oxindoles with alcohols
Scientific Reports, 2021 Although transition metal phosphides are well studied as electrocatalysts and hydrotreating catalysts, the application of metal phosphides in organic synthesis is rare, and cooperative catalysis between metal phosphides and supports remains unexplored ...
Shu Fujita +6 more
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3-Arylidene-2-oxindoles as Potent NRH:Quinone Oxidoreductase 2 Inhibitors
Molecules, 2023 The enzyme NRH:quinone oxidoreductase 2 (NQO2) plays an important role in the pathogenesis of various diseases such as neurodegenerative disorders, malaria, glaucoma, COVID-19 and cancer. NQO2 expression is known to be increased in some cancer cell lines.
Natalia A. Lozinskaya +11 more
doaj +1 more source
Molecules, 2021 An expeditious approach to the construction of spiroindenyl-2-oxindoles was developed via a palladium-catalyzed spirocyclization reaction of 2-bromoarylamides with vinyl bromides.
Shuai Yang, Yanghui Zhang
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Non-Palladium-Catalyzed Approach to the Synthesis of (E)-3-(1,3-Diarylallylidene)Oxindoles
Molecules, 2022 Two novel synthetic approaches for synthesizing (E)-3-(1,3-diarylallylidene)oxindoles from oxindole were developed. All previously reported methods for synthesizing 3-(1,3-diarylallylidene)oxindoles utilized palladium-catalyzed reactions as a key step to
Jahyun Koo +3 more
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Biology, 2021 The glycogen synthase kinase 3β (GSK-3β) is a protein kinase involved in regulating numerous physiological processes such as embryonic development, transcription, insulin action, cell division cycle and multiple neuronal functions.
Przemysław Czeleń, Beata Szefler
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Molecules, 2021 A synthetic route for the enantioselective construction of the tetracyclic spiro[indolizidine-1,3′-oxindole] framework present in a large number of oxindole alkaloids, with a cis H-3/H-15 stereochemistry, a functionalized two-carbon substituent at C-15 ...
Nihan Yayik +4 more
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Oxindoles and copper complexes with oxindole-derivatives as potential pharmacological agents [PDF]
Journal of the Brazilian Chemical Society, 2006 Oxindoles are endogenous compounds found in mammalian body fluids and tissues. Particularly, isatin (1H-indole-2,3-dione) and its derivatives have shown a variety of biological effects, including inhibition of monoamine oxidase, antibacterial, antifungal, antiviral and antiproliferative activities.
Cerchiaro, Giselle +1 more
openaire +3 more sources
Molecules, 2023 Thirty-three 1,3-dihydro-2H-indolin-2-one derivatives bearing α, β-unsaturated ketones were designed and synthesized via the Knoevenagel condensation reaction.
Taohua Pan +6 more
doaj +1 more source
AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury
, 2022 Hepatology, EarlyView.
Robert J. Fontana +6 more
wiley +1 more source
Molecules, 2019 The Pd-catalyzed intramolecular carbene C−H insertion of α-diazo-α-(methoxycarbonyl)acetamides to prepare oxindoles as well as β-lactams was studied.
Daniel Solé +4 more
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