Results 81 to 90 of about 2,987 (182)

Construction of highly enantioenriched spirocyclopentaneoxindoles containing four consecutive stereocenters via thiourea-catalyzed asymmetric Michael–Henry cascade reactions

Beilstein Journal of Organic Chemistry, 2017
The thiourea-catalyzed asymmetric synthesis of highly enantioenriched spirocyclopentaneoxindoles containing chiral amide functional groups using simple 3-substituted oxindoles and nitrovinylacetamide as starting materials was achieved successfully.
Yonglei Du, Jian Li, Kerong Chen, Chenglin Wu, Yu Zhou, Hong Liu   +5 more
doaj   +1 more source

Asymmetric α-amination of 3-substituted oxindoles using chiral bifunctional phosphine catalysts

Beilstein Journal of Organic Chemistry, 2016
A highly enantioselective α-amination of 3-substituted oxindoles with azodicarboxylates catalyzed by amino acids-derived chiral phosphine catalysts is reported. The corresponding products containing a tetrasubstituted carbon center attached to a nitrogen
Qiao-Wen Jin, Zhuo Chai, You-Ming Huang, Gang Zou, Gang Zhao   +4 more
doaj   +1 more source

Synthese des Oxindols [PDF]

Berichte der deutschen chemischen Gesellschaft, 1878
n ...
openaire   +1 more source

Organocatalytic asymmetric Michael addition of unprotected 3-substituted oxindoles to 1,4-naphthoquinone

Beilstein Journal of Organic Chemistry, 2012
We reported the first example of organocatalytic Michael addition of unprotected 3-prochiral oxindoles 1 to 1,4-naphthoquinone. Quinidine derivative (DHQD)2PYR was found to be able to catalyze this reaction in up to 83% ee, with moderate to excellent ...
Jin-Sheng Yu, Feng Zhou, Yun-Lin Liu, Jian Zhou   +3 more
doaj   +1 more source

Domino Reactions Enable Zn-Mediated Direct Synthesis of Spiro-Fused 2-Oxindole-α-Methylene-γ-Butyrolactones/Lactams from Isatin Derivatives and 2-(Bromomethyl)acrylates

Molecules
Isatin-derived spirocyclic cores are found in several biologically active molecules. Here, we report nucleophilic domino reactions for the synthesis of α-methylene-γ-butyrolactone/lactam containing spirocyclic oxindoles. The Zn-mediated one-step reaction
Prathap Reddy Mukthapuram, Amarnath Natarajan   +1 more
doaj   +1 more source

Oxindoles. V. Selective Solvolysis Reactions of Oxindole-Spirodimer

YAKUGAKU ZASSHI, 1985
YOSHIKAZU KONDO, YOJI MITADERA, SHIGEO NOZOE   +2 more
openaire   +2 more sources

Enantioselective cyclization reactions involving 3-isothiocyanato oxindoles: synthesis of spirocycles. [PDF]

RSC Adv
Edareh MH, Doraghi F, Farahani A, Ghasemi M, Mahdavi M.   +4 more
europepmc   +1 more source

Diazo-Preserving Radical Cascades for the Modular Photoinduced Synthesis of Oxindoles and Pyrazolones. [PDF]

Org Lett
Sarró P, Pleixats R, Vallribera A, Gimbert-Suriñach C, Granados A.   +4 more
europepmc   +1 more source

Organocatalytic Enantio- and Diastereoselective Synthesis of Dispirooxindole Derivatives with Adjacent Spirocyclic Centers via [4 + 2] Cycloadditions. [PDF]

J Org Chem
Hidalgo-León R, Trujillo-Sierra J, Sansano JM, Retamosa MG.   +3 more
europepmc   +1 more source

Thiophenol-mediated metal-free chemoselective conjugate reduction strategy for 3-alkylidene oxindoles. [PDF]

RSC Adv
Patil BR, Nichinde CB, Girase AS, Chaudhari SS, Kinage AK.   +4 more
europepmc   +1 more source