ABSTRACT Introduction Pain is highly prevalent among people with opioid use disorder (OUD), yet it is often undertreated. Whether opioid agonist treatment (OAT) improves pain outcomes is unknown among this target population. This research aimed to explore associations between pain severity and current OAT status in a longitudinal cohort of people who ...
Jie Yang +4 more
wiley +1 more source
Diagnosis and Management of Nitazene Dependence in Sydney, Australia: A Case Series
ABSTRACT Introduction Nitazenes are synthetic opioids with potent μ‐receptor activity. There are increasing reports of nitazene overdoses worldwide. We report on a case series of protonitazene and metonitazene dependence responding to high dose medication for the treatment of opioid dependence in both inpatient and outpatient settings.
Daniel Dutkiewicz +6 more
wiley +1 more source
Opioid Modulation of Major Neurotransmitter Systems: Acute, Chronic, and Withdrawal Effects
Opioids are widely used but also frequently misused drugs that affect multiple neurotransmitter systems, including dopaminergic, glutamatergic, GABAergic, serotonergic, and cholinergic pathways. Opioid‐induced neuroadaptations depend on the duration of drug exposure, with distinct changes also emerging following drug discontinuation.
Daniela Novakova +2 more
wiley +1 more source
Incidence and Associated Factors for Chronic Pain After ICU Discharge: A Prospective Study
ABSTRACT Background Survivors of critical illness are at high risk for developing chronic pain. However, evidence regarding new‐onset chronic pain in this specific population remains limited in China. Aims This study aimed to investigate the incidence of chronic pain among Chinese intensive care unit (ICU) survivors at 3 months after discharge and to ...
Jinyu Yin +6 more
wiley +1 more source
Comparative Short-term Risk of Severe Gastrointestinal Events Associated With Opioid Type Among Patients Receiving Glucagon-Like Peptide 1 Receptor Agonists. [PDF]
Bea S +7 more
europepmc +1 more source
Oxycodone at the Crossroads of Pain Management, Misuse, and Toxicological Investigation. [PDF]
Ślebioda D +5 more
europepmc +1 more source
The underutilization of oxycodone
openaire +2 more sources
Quadratus Lumborum versus Transversus Abdominis Plane Block with Oxycodone or Sufentanil for Recovery Quality After Laparoscopic Gastrointestinal Cancer Surgery: A Factorial Randomized Trial. [PDF]
Yang GW +5 more
europepmc +1 more source
Regarding: "Oxycodone Combined with Dexmedetomidine versus Oxycodone Alone and Sufentanil for Early Postoperative Analgesia and Perioperative Outcomes After Laparoscopic Surgery: A Randomized Controlled Trial" [Letter]. [PDF]
Luo J, Luo C, Pan W.
europepmc +1 more source
Complete recovery of thrombotic microangiopathy with severe acute kidney injury due to intravenous use of modified release oxycodone. [PDF]
Ezeakile M, Zirapury T.
europepmc +1 more source

